Alcohol-free transdermal analgesic composition and processes for manufacture and use thereof
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61F-013/00
A61K-009/70
출원번호
US-0412626
(2003-04-11)
발명자
/ 주소
Fishman,Robert
출원인 / 주소
All Natural FMG, Inc.
대리인 / 주소
McHale &
인용정보
피인용 횟수 :
9인용 특허 :
7
초록▼
The instant invention is directed toward a dermal delivery system composition comprising an aqueous base vehicle including American Emu oil, Isopropyl Palmitate (PROTACHEM IPP), PEG-8 (a polyethylene glycol available under the tradename PROTACHEM 400), methylsulfonylmethane (MSM) and SEPIGEL 305 (a
The instant invention is directed toward a dermal delivery system composition comprising an aqueous base vehicle including American Emu oil, Isopropyl Palmitate (PROTACHEM IPP), PEG-8 (a polyethylene glycol available under the tradename PROTACHEM 400), methylsulfonylmethane (MSM) and SEPIGEL 305 (a combination including polyacrylamide/C13-C14 Iso-paraffin and Laureth-7), in combination with an analgesic composition, such as ibuprofen, and to processes for the manufacture and use thereof.
대표청구항▼
What is claimed is: 1. An alcohol-free analgesic composition effective for transdermal delivery consisting essentially of: about 3% Emu Oil, about 3% Isopropyl Palmitate, about 4% PEG-8, about 0.75% methylsulfonylmethane, and a gelling agent including a combination of about 40% polyacrylamide, abou
What is claimed is: 1. An alcohol-free analgesic composition effective for transdermal delivery consisting essentially of: about 3% Emu Oil, about 3% Isopropyl Palmitate, about 4% PEG-8, about 0.75% methylsulfonylmethane, and a gelling agent including a combination of about 40% polyacrylamide, about 15% C13-C14 Iso-paraffin, about 5% Laureth-7 and sterile water sufficient to make 100% in an amount effective for gelling, about 10% of an analgesic composition, and sterile water sufficient to make 100%. 2. A composition for treating the discomfort of pain and/or inflammation in a patient comprising: about 3% Emu Oil, about 3% Isopropyl Palmitate, about 4% PEG-8, about 0.75% methylsulfonylmethane, and a gelling agent including a combination of about 40% polyacrylamide, about 15% C13-C14 Iso-paraffin, about 5% Laureth-7 and sterile water sufficient to make 100% in an amount effective for gelling, about 10% of an analgesic composition, and sterile water sufficient to make 100%. 3. A process for treating the discomfort of pain and/or inflammation and pain in a patient comprising: identifying a location of pain and/or inflammation in a patient; identifying a location or trigger points associated with pain/or inflammation in a patient; transdermally delivering to at least one location of trigger point said points an analgesic composition consisting essentially of about 3% Emu oil, 3% Isopropyl Palmitate and about 4% PEG-8, about 0.75% methylsulfonylmethane, a gelling agent including a combination of about 40% polyacrylamide, about 15% C13-C14 Iso-paraffin, about 5% Laureth-7 and sterile water sufficient to make 100% in an amount effective for gelling, about 10% of an analgesic composition, and sterile water sufficient to make 100%; whereby the discomfort of said pain and/or inflammation is treated. 4. A process for manufacturing an alcohol-free analgesic composition effective for transdermal delivery comprising: providing said analgesic composition; providing about 3% Emu oil in a high speed mixing apparatus; adding said analgesic composition to said Emu oil and mixing until a homogeneously blended composition is formed; adding about 3% Isopropyl Palmitate and about 4% PEG-8 to said homogeneously blend, and mixing for approximately 30 minutes; adding sterile water and mixing for approximately 5 minutes, to homogeneity; adding about 3% of a gelling agent including a combination of about 40% polyacrylamide, about 15% C13-C14 Iso-paraffin, about 5% Laureth-7 and sterile water sufficient to make 100%, and blending to achieve homogeneity and a gel-like consistency; and adding additional said gelling agent in 1% increments, if necessary, until desired gel consistency is achieved. 5. The product produced by the process of claim 4. 6. An alcohol-free transdermal delivery system consisting essentially of: about 3% Emu oil, about 3% Isopropyl Palmitate, about 4% PEG-8, about 0.75% methylsulfonylmethane, a gelling agent including a combination of about 40% polyacrylamide, about 15% C13-C14 Iso-paraffin, about 5% Laureth-7 and sterile water sufficient to make 100% in an amount effective for gelling, and sterile water sufficient to make 100%.
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이 특허에 인용된 특허 (7)
Kenneth B Kirby ; Berno I. R. Pettersson, Jr., Compositions for rapid and non-irritating transdermal delivery of pharmaceutically active agents and methods for formulating such compositions and delivery thereof.
Kirby, Kenneth B; Pettersson, Berno, Compositions for rapid and non-irritating transdermal delivery of pharmaceutically active agents and methods for formulating such compositions and delivery thereof.
Harm M. Deckers CA; Gijs van Rooijen CA; Joseph Boothe CA; Janis Goll CA; Maurice M. Moloney CA, Products for topical applications comprising oil bodies.
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