$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Amplification of nucleic acids with electronic detection 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-015/00
  • C01Q-001/68
  • C12P-019/34
  • C12P-019/00
출원번호 US-0238351 (1999-01-27)
발명자 / 주소
  • Kayyem,Jon Faiz
  • Bamdad,Cynthia
출원인 / 주소
  • Clinical Mirco Sensors, Inc.
대리인 / 주소
    Dorsey &
인용정보 피인용 횟수 : 17  인용 특허 : 88

초록

The invention relates to compositions and methods useful in the detection of nucleic acids using a variety of amplification techniques, including both signal amplification and target amplification. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the n

대표청구항

대표청구항이 없습니다.

이 특허에 인용된 특허 (88)

  1. Stavrianopoulos Jannis (New York NY) Rabbani Elazar (New York NY) Abrams Samuel B. (New York NY) Wetmur James G. (Scardsdale NY), Analyte detection by means of energy transfer.
  2. Ribi Hans O. (Hillsborough CA) Guion Todd (San Mateo CA) Shafer Paul T. (Campbell CA), Analyte detection with multilayered bioelectronic conductivity sensors.
  3. Engelhardt Dean (New York NY) Rabbani Elazar (New York NY) Kline Stanley (Brooklyn NY) Stavrianopoulos Jannis G. (New York NY) Kirtikar Dollie (Elmhurst NY), Base moiety-labeled detectable nucleatide.
  4. Lennox R. Bruce,CAX, Biosensor device and method.
  5. Ribi Hans O. (Mateo CA), Biosensors employing electrical, optical and mechanical signals.
  6. Rabbani Elazar (New York NY) Engelhardt Dean L. (New York NY), Composition and method for the detection of the presence of a polynucleotide sequence of interest.
  7. Stavrianopoulos Jannis G. (New York NY), Compound and detectable molecules having an oligo- or polynucleotide with modifiable reactive group.
  8. Bowers Mark L. (Watertown MA) Druy Mark A. (Arlington MA) Durfor Charles N. (Arlington MA) Smith H. Gilbert (Littleton MA) Tripathy Sukant K. (Arlington MA) Yenser Barbara A. (Manchester NH), Covalently coupled cofactor modified electrodes and methods of synthesis and use.
  9. Smith Lloyd M. (South Pasadena CA) Fung Steven (Palo Alto CA), Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for t.
  10. Stavrianopoulos Jannis G. (New York NY), Detectable molecules, method of preparation and use.
  11. Stavrianopoulos Jannis G. (New York NY), Detectable molecules, method of preparation and use.
  12. Stavrianopoulos Jannis G. (New York NY), Detectable molecules, method of preparation and use.
  13. Stavrianopoulos Jannis G. (New York NY), Detectable molecules, method preparation and use.
  14. Brow Mary Ann D. ; Hall Jeff Steven Grotelueschen ; Lyamichev Victor ; Olive David Michael ; Prudent James Robert, Detection of nucleic acid sequences by invader-directed cleavage.
  15. Bannwarth Wilhelm (Upper Saddle River NJ) Muller Francis (Basel CHX), Detection of nucleic acids using a hairpin forming oligonucleotide primer and an energy transfer detection system.
  16. Ershow Gennady Moiseevich,RUX ; Kirillov Evgenii Vladislavovich,RUX ; Mirzabekov Andrei Darievich,RUX, Device of dispensing micro doses of aqueous solutions of substances onto a carrier and device for carrying out said meth.
  17. Garnier Francis,FRX, Electrically conductive electroactive functionalized conjugated polymers, and uses thereof.
  18. Willner Itamar (Mevasseret-Zion ILX) Katz Evgeny (Jerusalem ILX) Riklin Azalia (Jerusalem ILX) Kasher Ron (Jerusalem ILX) Shoham Benjamin (Jerusalem ILX), Electrobiochemical analytical method and electrodes.
  19. Hill Hugh A. O. (Oxford GB2) Libor Susan I. (Oxford GB2), Electrochemical assay for nucleic acids and nucleic acid probes.
  20. Skotheim Terje A. (Shoreham NY) Okamoto Yoshiyuki (Fort Lee NJ) Hale Paul D. (Northport NY), Electrochemical biosensor based on immobilized enzymes and redox polymers.
  21. O\Daly John P. (Carrboro NC) Henkens Robert W. (Durham NC) Zhao Junguo (Chapel Hill NC) Zhang Honghua (Chapel Hill NC), Electrochemical immunoassay methods.
  22. Forrest Gordon C. (East Morsley GB2) Rattle Simon J. (Quainton GB2) Robinson Grenville A. (London GB2) Hill Hugh A. O. (Oxford GB2), Electrochemical methods of assay.
  23. Gilmartin Markas A. T.,GB2, Electrodes and metallo isoindole ringed compounds.
  24. Kayyem Jon F. ; O'Connor Stephen D. ; Gozin Michael ; Yu Changjun ; Meade Thomas J., Electrodes linked via conductive oligomers to nucleic acids.
  25. Brakel Christine L. (Brightwaters NY) Cook Alan F. (Cedar Groove NJ) Vuocolo Edmund (Bronx NY), End labeled nucleotide probe.
  26. Malek Lawrence T. (Brampton CAX) Davey Cheryl (Toronto CAX) Henderson Graham (Mississauga CAX) Sooknanan Roy (Toronto CAX), Enhanced nucleic acid amplification process.
  27. Hashimoto Koji,JPX ; Ito Keiko,JPX ; Ishimori Yoshio,JPX ; Gotoh Masanori,JPX, Gene detection method.
  28. Englehardt Dean L. (New York NY) Rabbani Elazar (New York NY), Hybridization method for the detection of genetic material.
  29. Heller Adam (Austin TX) Maidan Ruben (Austin TX), Interferant eliminating biosensor.
  30. Bergstrm Jan (Blinge SEX) Lfaas Stefan (Uppsala SEX) Johnsson Bo (Storvreta SEX), Matrix coating for sensing surfaces capable of selective biomolecular interactions, to be used in biosensor systems.
  31. Wilding Peter (Paoli PA) Kricka Larry J. (Berwyn PA), Mesoscale polynucleotide amplification devices.
  32. Bruckenstein Stanley (Amherst NY) Adinolfe Nancy (Pleasant Valley NY), Method and apparatus for compensation of double layer charging current in electrochemical cells.
  33. Sargent Jeannine P. (22270 Kendle St. Cupertino CA 95014) Marks Jeff (4730 Cielo Vista Way San Jose CA 95129), Method and apparatus for determining the sequence of polynucleotides.
  34. Riviello John M. (2430 Paul Minnie Ave. Santa Cruz CA 95062) Wallace Gordon (35 Francis Street Wollongong NSW AUX) Sadik Omowunmi A. (c/o Dr PO Ogunbona ; PO Box 19 Keiraville NSW 2500 AUX), Method and apparatus for pulsed electrochemical detection using polymer electroactive electrodes.
  35. MacConnell William P. (Cardiff CA), Method and means for annealing complementary nucleic acid molecules at an accelerated rate.
  36. Stavrianopoulos Jannis G. (New York NY) Kirtikar Dollie (Elmhurst NY) Johnston Kenneth H. (New York NY) Thalenfeld Barbara E. (New York NY), Method and structures employing chemically-labelled polynucleotide probes.
  37. Okamoto Tadashi,JPX ; Tomida Yoshinori,JPX ; Yamamoto Nobuko,JPX ; Kawaguchi Masahiro,JPX ; Makino Keisuke,JPX ; Murakami Akira,JPX, Method for detecting a target nucleic acid by using an interaction of two kinds of reagents.
  38. Magda Darren (Cupertino CA) Sessler Jonathan L. (Austin TX) Iverson Brent L. (Austin TX) Sansom Petra I. (Austin TX) Crofts Shaun P. (Campbell CA), Method of expanded porphyrin-oligonucleotide conjugate synthesis.
  39. Ershov Gennady Moiseevich,RUX ; Timofeev Eduard Nikolaevich,RUX ; Ivanov Igor Borisovich,RUX ; Florentiev Vladimir Leonidovich,RUX ; Mirzabekov Andrei Darievich,RUX, Method of immobilizing water-soluble bioorganic compounds on a capillary-porous carrier.
  40. Ershov Gennady Moiseevich,RUX ; Mirzabekov Andrei Darievich,RUX, Method of manufacturing a matrix for the detection of mismatches.
  41. Stavrianopoulos Jannis G. (New York NY), Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group.
  42. Nilsen Thor W. (Glen Mills PA) Prensky Wolf (Fairlawn NJ), Methods for detecting and assaying nucleic acid sequences.
  43. Heller Michael James ; O'Connell James Patrick ; Juncosa Robert David ; Sosnowski Ronald George ; Jackson Thomas Ratcliffe, Methods for hybridization analysis utilizing electrically controlled hybridization.
  44. Khrapko Konstantin R. (Moscow RUX) Khorlin Alexandr A. (Moscow RUX) Ivanov Igor B. (Moskovskaya RUX) Ershov Gennady M. (Moscow RUX) Lysov Jury P. (Moscow RUX) Florentiev Vladimir L. (Moscow RUX) Mirz, Methods of DNA sequencing by hybridization based on optimizing concentration of matrix-bound oligonucleotide and device.
  45. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Methods of using labeled nucleotides.
  46. Marks Robert,ILX ; Lellouche Jean-Paul,ILX, Micro-circuit system with array of functionalized micro-electrodes.
  47. Mirzabekov Andrei Darievich,RUX ; Lysov Yuri Petrovich,RUX ; Shick Valentine Vladimirovich ; Dubiley Svetlana Alekseevna,RUX, Microchip method for the enrichment of specific DNA sequences.
  48. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Modified nucleotides and methods of preparing and using same.
  49. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Modified nucleotides and polynucleotides and complexes form therefrom.
  50. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Modified polynucleotides and methods of preparing same.
  51. Heller Michael J. (Encinitas CA) Tu Eugene (San Diego CA) Butler William F. (Carlsbad CA), Molecular biological diagnostic systems including electrodes.
  52. Bamdad Cynthia C. (Sharon MA) Sigal George B. (Arlington MA) Strominger Jack L. (Lexington MA) Whitesides George M. (Newton MA), Molecular recognition at surfaces derivatized with self-assembled monolayers.
  53. Maracas George N., Molecular sensing apparatus.
  54. Keen Randy E., Molecular wire injection sensors.
  55. Wohlstadter Jacob N. ; Wilbur James ; Sigal George ; Martin Mark ; Guo Liang-Hong ; Fischer Alan ; Leland Jon ; Billadeau Mark A., Multi-array, multi-specific electrochemiluminescence testing.
  56. Ribi Hans O. (San Mateo CA) Guion Todd (Palo Alto CA) Shafer Paul T. (Burlingame CA), Multilayered bioelectronic sensors.
  57. Davey Cheryl (Toronto CAX) Malek Lawrence T. (Brampton CAX), Nucleic acid amplification process.
  58. Stavrianopoulos Jannis G. (New York NY), Nucleic acid hybridization assay and detectable molecules useful in such assay.
  59. Meade Thomas J. (Altadena CA) Kayyem Jon F. (Pasadena CA) Fraser Scott E. (Newport Beach CA), Nucleic acid mediated electron transfer.
  60. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  61. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  62. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  63. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  64. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  65. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  66. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  67. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  68. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  69. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  70. Meade Thomas J. ; Kayyem Jon Faiz ; Fraser Scott E., Nucleic acid mediated electron transfer.
  71. Albagli David (Palo Alto CA) VanAtta Reuel (Mountain View CA) Wood Michael (Palo Alto CA), Nucleic acid sequence detection employing amplification probes.
  72. Albagli David ; VanAtta Reuel ; Wood Michael, Oligonucleotides containing base-free linking groups with photoactivatable side chains.
  73. Fawcett Newton C. (Hattiesburg MS) Evans Jeffrey A. (Hattiesburg MS), Piezoelectric device for detection of polynucleotide hybridization.
  74. Teoule Robert,FRX ; Roget Andre,FRX ; Livache Thierry,FRX ; Barthet Christelle,FRX ; Bidan Gerard,FRX, Preparation of a electronically conductive polymer/nucleotide copolymer.
  75. Mullis Kary B. (Kensington CA), Process for amplifying nucleic acid sequences.
  76. Mullis Kary B. (Kensington CA) Erlich Henry A. (Oakland CA) Arnheim Norman (Woodland Hills CA) Horn Glenn T. (Emeryville CA) Saiki Randall K. (Richmond CA) Scharf Stephen J. (Berkeley CA), Process for amplifying, detecting, and/or-cloning nucleic acid sequences.
  77. Nilsen Thor W. (Glen Mills PA) Prensky Wolf (Fairlawn NJ), Reagents for detecting and assaying nucleic acid sequences.
  78. Collins Mark L. (Walnut Creek CA) Horn Thomas (Berkeley CA) Sheridan Patrick J. (San Leandro CA) Warner Brian D. (Martinez CA) Urdea Michael S. (Alamo CA), Reduction of nonspecific hybridization by using novel base-pairing schemes.
  79. Lizardi Paul M.,MXX, Rolling circle replication reporter systems.
  80. Bannwarth Wilhelm (Rheinfelden-Beuggen DEX) Mller Francis (Basel CHX), Ruthenium-lumazine energy transfer systems.
  81. Bergstrm Jan (Blinge SEX) Lfas Stefan (Uppsala SEX) Johnsson Bo (Storvreta SEX), Sensing surfaces capable of selective biomolecular interactions, to be used in biosensor systems.
  82. Ansorge Wilhelm,DEX ; Voss Hartmut,DEX ; Stegemann Josef,DEX ; Wiemann Stefan,DEX, Simultaneous sequencing of nucleic acids.
  83. Walker George T. (Chapel Hill NC), Strand displacement amplification.
  84. Marble Herbert A. (Boulder CO) Davis Robert H. (Boulder CO), Strategy for the production of RNA from immobilized templates.
  85. Collins Mark L., Target and background capture methods and apparatus for affinity assays.
  86. Barany Francis (New York NY) Zebala John (New York NY) Nickerson Deborah (Seattle WA) Kaiser ; Jr. Robert J. (Seattle WA) Hood Leroy (Seattle WA), Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease.
  87. Beebe Thomas P. (Salt Lake City UT) Rabke-Clemmer Carol E. (Rochester NY), Thiol labeling of DNA for attachment to gold surfaces.
  88. Mikkelsen Susan R. (Montreal CAX) Millan Kelly M. (LaSalle CAX) Spurmanis Aleksandrs J. (Montreal CAX), Voltammetric sequence-selective sensor for target polynucleotide sequences.

이 특허를 인용한 특허 (17)

  1. Wright, David Walter; Aiello, Dominic; Clark, Robert, Apparatus and methods for manipulating deformable fluid vessels.
  2. Wright, David Walter; Aiello, Dominic, Apparatus, devices, and methods for manipulating deformable fluid vessels.
  3. Wright, David Walter; Aiello, Dominic; Kroehl, Peter; Kayyem, Jon Faiz; Gray, Darren Scott, Cartridge for performing assays in a closed sample preparation and reaction system.
  4. Wright, David Walter; Aiello, Dominic, Devices and methods for manipulating deformable fluid vessels.
  5. Brown, Bradley Adam; Martinez, Milena Iacobelli; Freeman-Cook, Lisa Lynn; Harvey, John Jay; Shaw, Christine J.; Al-Khouri, Anna Maria, Electrochemical detection of bacterial and/or fungal infections.
  6. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  7. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  8. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  9. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  10. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  11. O'Connor, Stephen D.; Kayyem, Jon Faiz; Meade, Thomas J., Electronic methods for the detection of analytes.
  12. Kayyem, Jon Faiz; Ford, Sean; Pamula, Vamsee K.; Srinivasan, Vijay; Corey, Scott; Murphy, Brian; Wright, David Walter; Aiello, Dominic, Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation.
  13. Corey, Scott; Murphy, Brian; Schneider, Eric; Wright, David Walter; Aiello, Dominic; Fish, Andrew; Srinivasan, Jay; Maltezos, George, Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system.
  14. Kayyem, Jon Faiz; Srinivasan, Jayashankar; Ford, Sean, Integrated multiplex target analysis.
  15. Brenner, Sydney, Methods and compositions for isolating nucleic acid sequence variants.
  16. Brenner, Sydney, Methods and compositions for isolating nucleic acid sequence variants.
  17. Baker, Tony, Removal of molecular assay interferences.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로