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Suspension aerosol formulations 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/00
  • A01N-025/02
  • A61L-009/04
출원번호 US-0455874 (1995-05-31)
발명자 / 주소
  • Schultz,Robert K.
  • Schultz,David W.
  • Moris,Robert A.
출원인 / 주소
  • 3M Innovative Properties Company
인용정보 피인용 횟수 : 0  인용 특허 : 87

초록

Pharmaceutical suspension aerosol formulations containing a therapeutically effective amount of a drug and HFC 134a, HFC 227, or a mixture thereof.

대표청구항

What is claimed is: 1. A pharmaceutical suspension aerosol formulation comprising: (i) particulate drug; (ii) 1,1,1,2,3,3,3-heptafluoropropane as propellant; and (iii) ethanol in an amount of 5 to about 15 percent by weight, wherein the formulation contains no surfactant. 2. The pharmaceutical s

이 특허에 인용된 특허 (87)

  1. Thiel Charles G. (Saint Paul MN), Aerosol compositions containing finely divided solid materials.
  2. Johnson Keith A. (Holmes Beach FL), Aerosol drug formulations.
  3. Akehurst Rachel Ann,GBX ; Taylor Anthony James,GBX ; Wyatt David Andrew,GBX, Aerosol formulation containing P134a and particulate medicament.
  4. Taylor Anthony James,GBX ; Burnell Patricia Kwong Phieu,GBX, Aerosol formulation containing a particulate medicament.
  5. Taylor Anthony James,GBX ; Burnell Patricia Kwong Phieu,GBX, Aerosol formulation containing a particulate medicament.
  6. Taylor Anthony James,GBX ; Neale Philip John,GBX, Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant.
  7. Akehurst Rachel Ann,GBX ; Taylor Anthony James,GBX ; Wyatt David Andrew,GBX, Aerosol formulation containing particulate formoterol, propellant and polar cosolvent.
  8. Akehurst, Rachel Ann; Taylor, Anthony James; Wyatt, David Andrew, Aerosol formulation containing particulate formoterol, propellant and polar cosolvent.
  9. Akehurst Rachel Ann,GBX ; Taylor Anthony James,GBX ; Wyatt David Andrew,GBX, Aerosol formulations containing P134A and/or P227 and particulate medicament.
  10. Akehurst Rachel Ann,GB3 ; Taylor Anthony James,GB3 ; Wyatt David Andrew,GB3, Aerosol formulations containing P134a and particulate medicament.
  11. Akehurst Rachel Ann,GBX ; Taylor Anthony James,GBX ; Wyatt David Andrew,GBX, Aerosol formulations containing P134a and particulate medicament.
  12. Akehurst Rachel Ann,GBX ; Taylor Anthony James,GBX ; Wyatt David Andrew,GBX, Aerosol formulations containing P134a and particulate medicament.
  13. Akehurst Rachel Ann (Ware GB3) Taylor Anthony James (Ware GB3) Wyatt David Andrew (Ware GB3), Aerosol formulations containing P134a and particulate medicaments.
  14. Akehurst Rachel Ann,GB3 ; Taylor Anthony James,GB3 ; Wyatt David Andrew,GB3, Aerosol formulations containing P134a and particulate medicaments.
  15. Akehurst Rachel Ann (Ware GB3) Taylor Anthony James (Ware GB3) Wyatt David Andrew (Ware GB3), Aerosol formulations containing P134a and salbutamol.
  16. Taylor Anthony James,GB3 ; Neale Philip John,GB3, Aerosol formulations containing beclomethasone dipropionate-1, 1, 1, 2-tetrafluoroethane solvate.
  17. Akehurst Rachel Ann (Ware GB3) Taylor Anthony James (Ware GB3) Wyatt David Andrew (Ware GB3), Aerosol formulations containing propellant 134a and fluticasone propionate.
  18. Akehurst Rachel Ann,GBX ; Taylor Anthony James,GBX ; Wyatt David Andrew,GBX, Aerosol formulations containing salmeterol xinafoate, an anticholinergic agent and tetrafluoroethane.
  19. Evans Richard M. (Westwood MA) Farr Stephen J. (Llandaf GB7), Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol.
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  25. Phillipps Gordon H. (Wembley GB2) Bain Brian M. (Chalfont St. Peter GB2) Steeples Ian P. (Ruislip Manor GB2) Williamson Christopher (Cobham GB2), Androstane carbothioates.
  26. Bartlett Philip L. (Wilmington DE) Bivens Donald B. (Kennett Square PA) Lunger Brooks S. (Coatesville PA) Yokozeki Akimichi (Greenville DE), Azeotropic and azeotrope-like compositions of 1,1,2,2-tetrafluoroethane.
  27. Schultz Robert K. ; Schultz David W., Beclomethasone solution aerosol formulations.
  28. Tarlochan S. Purewal GB; David J. Greenleaf GB, CRC-free medicinal aerosol formulations of 1,1,1,2-tetrafluoroethane (134A) with polar adjuvant.
  29. Akehurst Rachel Ann (Ware GB3) Taylor Anthony James (Ware GB3) Wyatt David Andrew (Ware GB3), Canister containing aerosol formulations containing P134a and particulate medicaments.
  30. Akehurst Rachel Ann (Ware GB3) Taylor Anthony James (Ware GB3) Wyatt David Andrew (Ware GB3), Canister containing aerosol formulations containing P134a and particulate medicaments.
  31. Akehurst Rachel Ann,GB3 ; Taylor Anthony James,GB3 ; Wyatt David Andrew,GB3, Canister containing aerosol formulations containing P134a and particulate medicaments.
  32. Akehurst Rachel Ann (Ware GB3) Taylor Anthony James (Ware GB3) Wyatt David Andrew (Ware GB3), Canisters containing aerosol formulations containing P134a and fluticasone propionate.
  33. Berry Julianne ; Sequeira Joel A. ; Chaudry Imtiaz A., Chlorofluorocarbon-free mometasone furoate aerosol formulations.
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  36. Marecki Paul E., Device for delivering an aerosol.
  37. Marecki Paul E. (May Township ; Washington County MN), Device for delivering an aerosol.
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  39. Tzou Tsi-Zong ; Schultz Robert K. ; Ross Danna L., Flunisolide aerosol formulations.
  40. Smits Guide F. (Wijengem BEX) Grnbauer Henri J. M. (Oostburg NLX), Foaming system for rigid urethane and isocyanurate foams.
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  44. Badger Alison M. (Bryn Mawr PA) Cheeseman Elaine N. (Phoenixville PA) DiMartino Michael J. (Philadelphia PA) Dorman James W. (West Chester PA) Mirabelli Christopher K. (Exton PA) Picker Donald H. (Me, Immunomodulatory azaspiranes.
  45. Gumprecht William H. (Wilmington DE), Liquid phase halogen exchange process for the manufacture of 1,1,1,2-tetrafluoroethane.
  46. Bell ; Stephen L., Manufacture of halogenated compounds.
  47. Akehurst Rachel Ann,GBX ; Taylor Anthony James,GBX ; Wyatt David Andrew,GBX, Medicaments.
  48. Latter Victoria S. (Beckenham GB2) Gutteridge Winston E. (Beckenham GB2) Hudson Alan T. (Beckenham GB2), Medicaments.
  49. Latter Victoria S. (Beckenham GB2) Gutteridge Winston E. (Beckenham GB2) Hudson Alan T. (Beckenham GB2), Medicaments.
  50. Palmer James B. D. (Greenford GBX), Medicaments.
  51. Neale Philip John (Ware GB3) Taylor Anthony James (Ware GB3), Medicaments for treating respiratory disorders.
  52. Purewal Tarlochan S. (Leamington Spa GB2) Greenleaf David J. (Loughborough GB2), Medicinal aerosol formulations.
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  59. Purewal Tarlochan S.,GB2 ; Greenleaf David J.,GB2, Medicinal aerosol formulations.
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  61. Purewal Tarlochan S.,GB2 ; Greenleaf David J.,GB2, Medicinal aerosol formulations.
  62. Oliver Martin J.,GBX ; Paling Simon G.,GBX ; Jinks Philip A.,GBX ; Jaiswal Sukhbinder K.,GBX, Medicinal aerosol formulations of formoterol.
  63. Byron Peter R. (Richmond VA) Blondino Frank E. (Richmond VA), Metered dose inhaler fomulations which include the ozone-friendly propellant HFC 134a and a pharmaceutically acceptable.
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  65. Evans Richard M. (Norwood MA) Farr Stephen J. (Cardiff GB7), Method of preparing medical aerosol formulations including drug dissolved in reverse micelles.
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  67. Fassberg, Julianne; Sequeira, Joel A.; Chaudry, Imtiaz A.; Kopcha, Michael, Non-chlorofluorocarbon aerosol formulations.
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  71. Akehurst Rachel Ann,GBX ; Taylor Anthony James,GBX ; Wyatt David Andrew,GBX, Pharmaceutical aerosol formulation containing a particulate medicament, a propellant and substantially free of a surfactant.
  72. Hans-Hermann Weil DE; Ottfried Daab DE, Pharmaceutical composition using a mixture of propellant gases for a metered dose inhaler.
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  75. Kamiya Tetsuro (Tochigi JPX) Inoue Takeshi (Tochigi JPX) Yorozu Hidenori (Tochigi JPX) Eguchi Yasuteru (Tochigi JPX) Tsujii Kaoru (Tochigi JPX), Precutaneous absorption accelerator and preparation containing same.
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  80. Cook Peter Barry (Standon EN) Hunt John Harold (Theydon Bois EN), Steroidal aerosol compositions and process for the preparation thereof.
  81. Liversidge Gary G. (West Chester PA) Cundy Kenneth C. (Pottstown PA) Bishop John F. (Rochester NY) Czekai David A. (Honeoye Falls NY), Surface modified drug nanoparticles.
  82. Schultz, Robert K.; Schultz, David W.; Oliver, Martin J.; Moris, Robert A.; Jinks, Philip A., Suspension aerosol formulations.
  83. Hans-Hermann Weil DE; Ottfried Daab DE, Suspension aerosol formulations of pharmaceutical products.
  84. Durbak Taras (Irvington NJ) Nersesian Ara (Livingston NJ), Suspension composition of benzocaine.
  85. Hagen Nicholas S. (Doylestown PA) Lamon Kim D. (Maple Glen PA), Triamcinolone acetonide for the treatment of allergic rhinitis.
  86. Hansen Lloyd Frank (Campbell Hall NY), Unitary therapeutic aerosol dispenser.
  87. Schultz Robert K. (Shoreview MN) Quessy Stephen N. (St. Paul MN), Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations.
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