초록 ▼

A formulation effective in reducing the pH in a menstruating vagina or in a tampon inserted therein to below pH 5.5, comprising (a) 3-80% by weight of a solid organic acid polymer; (b) 92-15% by weight of a solid organic acid; and (c) 5-30% of a wetting agent. Also disclosed is a delivery system fo

A formulation effective in reducing the pH in a menstruating vagina or in a tampon inserted therein to below pH 5.5, comprising (a) 3-80% by weight of a solid organic acid polymer; (b) 92-15% by weight of a solid organic acid; and (c) 5-30% of a wetting agent. Also disclosed is a delivery system for releasing an active agent comprising: (a) a deposition comprising the active agent; and (b) a polymeric support on which the deposition is deposited. The delivery system is especially useful in a catamenial tampon for insertion in a human vagina which comprises (a) an inner core comprising an absorbent material; (b) an outer layer comprising a liquid permeable material; and (c) the delivery system.

대표청구항 ▼

The invention claimed is: 1. A tampon for insertion in a human vagina comprising: (a) an inner absorbent core, an outer covering layer and at least one polymeric support comprising one or more layers wherein said polymeric support is positioned on the inner absorbent core and underneath the outer c

The invention claimed is: 1. A tampon for insertion in a human vagina comprising: (a) an inner absorbent core, an outer covering layer and at least one polymeric support comprising one or more layers wherein said polymeric support is positioned on the inner absorbent core and underneath the outer covering layer; and (b) a deposition covering at least a part of said polymeric support, the deposition comprising an active agent; wherein the polymeric support is in the form of a strip and comprises a non-woven polymer material or a non-woven cloth material. 2. A tampon according to claim 1 wherein said strip consists of a plurality of layers. 3. A tampon according to claim 2 wherein said strip consists of 2-16 layers. 4. A tampon according to claim 1 wherein said polymeric support comprises a plurality of strips. 5. A tampon according to claim 4 wherein said polymeric support comprises 3 strips. 6. A tampon according to claim 1 wherein the poylmeric support comprises a polymer selected from the group consisting of polypropylene, polyethylene, cellulose, and cellulose derivatives. 7. A tampon according to claim 1 wherein said active agent comprises 3-80% by weight of solid organic acid polymer. 8. A tampon according to claim 7 wherein said organic acid polymer is polylactic acid in the range of from approximately 200-2000 MW. 9. A tampon according to claim 8 wherein said organic acid polymer is lactide. 10. A tampon according to claim 9 wherein said organic acid polymer is DL-lactide or L-lactide. 11. A tampon according to claim 7 wherein said active agent additionally comprises 92-15% by weight of a solid organic acid. 12. A tampon according to claim 7 wherein said active agent additionally comprises 5-30% of a wetting agent. 13. A tampon according to claim 7 wherein said active agent additionally comprises 92-15% by weight of a solid organic acid and 5-30% of a wetting agent. 14. A tampon according to claim 11 or 13 wherein said solid organic acid is selected from the group consisting of citric, malic, maleic, fumaric, succinic, tartaric and oxalic acids. 15. A tampon according to claim 12 or 13 wherein said wetting agent is selected from the group consisting of glycerol, polyethylene glycol (PEG), polypropylene glycol (PPG) and surfactants with an HLB ranging from 10 to 18. 16. A tampon according to claim 1 wherein the components of said deposition are dissolved in a solvent and the deposition is deposited on said polymeric support by evaporation of said solvent. 17. A tampon according to claim 1 wherein said active agent comprises an anti-inflammatory agent. 18. A tampon according to claim 17 wherein said active agent additionally comprises 3-80% by weight of solid organic acid polymer. 19. A tampon according to claim 18 wherein said organic acid polymer is polylactic acid in the range of from approximately 200-2000 MW. 20. A tampon according to claim 19 wherein said organic acid polymer is lactide. 21. A tampon according to claim 20 wherein said organic acid polymer is DL-lactide or L-lactide. 22. A tampon according to claim 18 wherein said active agent additionally comprises 92-15% by weight of a solid organic acid. 23. A tampon according to claim 18 wherein said active agent additionally comprises 5-30% of a wetting agent. 24. A tampon according to claim 18 wherein said active agent additionally comprises 92-15% by weight of a solid organic acid and 5-30% of a wetting agent. 25. A tampon according to claim 22 or 24 wherein said solid organic acid is selected from the group consisting of citric, malic, maleic, fumaric, succinic, tartaric and oxalic acids. 26. A tampon according to claim 23 or 24 wherein said wetting agent is selected from the group consisting of glycerol, polyethylene glycol (PEG), polypropylene glycol (PPG) and surfactants with an HLB ranging from 10 to 18.