IPC분류정보
| 국가/구분 |
United States(US) Patent
등록
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| 국제특허분류(IPC7판) |
|
| 출원번호 |
US-0729026
(2003-12-05)
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발명자
/ 주소 |
- Bolling,Steven F.
- Gharib,Morteza
- Aldea,Gabriel
- Gaddis,Mary Lynn
- Viole,Anthony J.
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| 출원인 / 주소 |
- Orqis Medical Corporation
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| 대리인 / 주소 |
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| 인용정보 |
피인용 횟수 :
42 인용 특허 :
181 |
초록
▼
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and method of using same. One embodiment of the extracardiac system comprises a pump configured to be implanted subcuta
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and method of using same. One embodiment of the extracardiac system comprises a pump configured to be implanted subcutaneously in a minimally-invasive procedure, wherein the pump can draw blood through an inflow conduit, and can discharge blood through an outflow conduit. The pump may be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart. The conduits can be housed in a multi-lumen catheter.
대표청구항
▼
What is claimed is: 1. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof, is substantially below that of the patient's heart
What is claimed is: 1. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof, is substantially below that of the patient's heart when healthy; a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculature wherein the blood may travel in reverse directions within the conduit, wherein the conduit further comprises: an inflow port; a first lumen fluidly coupled with the inflow port such that blood can be directed from the inflow port into the first lumen; a second lumen fluidly coupled to the pump such that blood can be pumped from the pump through the second lumen; an outflow port fluidly coupled with the second lumen such that blood can be directed from the second lumen through the outflow port; a first cannula positioned between the pump and the first lumen; and a second cannula positioned between the second lumen and the pump wherein the conduit is configured such that the inflow port can be positioned at a first location within the patient's vasculature and the outflow port can be positioned at a second location within the vasculature. 2. The system of claim 1, wherein the conduit comprises a multi-lumen catheter. 3. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof, is substantially below that of the patient's heart when healthy; a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculatore wherein the blood may travel in reverse directions within the conduit; a motor operatively coupled to the pump; and a programmable controller electronically coupled to the motor and configured to control the speed of the motor and the output of the pump, wherein the conduit is comprised of a material that is sufficiently flexible so as not to prevent the patient from being ambulatory. 4. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof, is substantially below that of the patient's heart when healthy; and a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculature wherein the blood may travel in reverse directions within the conduit; wherein the conduit is configured to direct blood from a first peripheral vessel to a second vessel. 5. The system of claim 4, wherein the first peripheral vessel is a femoral artery and the second vessel is the aorta. 6. The system of claim 4, wherein the conduit comprises a multi-lumen catheter. 7. The system of claim 4, wherein the pump is sized and configured to discharge blood at volumetric flow rates between about 0.1 liters/min and about 3.0 liters/min. 8. The system of claim 4, wherein the system is configured to be applied to the patient through a single cannulation site. 9. The system of claim 4, wherein the pump comprises a rotary pump. 10. The system of claim 4, wherein the conduit is comprised of a material that is sufficiently flexible so as not to prevent the patient from being ambulatory. 11. The system of claim 4, wherein the pump is configured to be implanted within the patient. 12. The system of claim 4, wherein the first peripheral vessel is a femoral artery and the second vessel is an axillary artery. 13. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof, is substantially below that of the patient's heart when healthy; and a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculature wherein the blood may travel in reverse directions within the conduit; wherein a first location is within a left femoral artery and a second location is in a descending aorta proximate an arterial branch. 14. The system of claim 13, wherein the second location is proximate a subclavian artery. 15. The system of claim 13, wherein the second location is proximate a mesenteric artery. 16. The system of claim 13, wherein the conduit comprises a multi-lumen catheter. 17. The system of claim 13, wherein the pump is sized and configured to discharge blood at volumetric flow rates between about 0.1 liters/min and about 3.0 liters/min. 18. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an avenge flow rate that, during normal operation thereof is substantially below that of the patient's heart when healthy; a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculature wherein the blood may travel in reverse directions within the conduit; a motor operatively coupled to the pump; and a programmable controller electronically coupled to the motor and configured to control the speed of the motor and the output of the pump, wherein the pump comprises a rotary pump. 19. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof, is substantially below that of the patient's heart when healthy; and a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculature wherein the blood may travel in reverse directions within the conduit; wherein the pump comprises a rotary pump, and wherein the system is configured to be applied to the patient through a single cannulation site. 20. The system of claim 19, wherein the conduit comprises a multi-lumen catheter. 21. The system of claim 19, wherein a first location of the patient's vasculature is in a femoral artery and a second location is in the aorta. 22. The system of claim 19, wherein a first location of the patient's vasculature is in a femoral artery and a second location is in an axillary artery. 23. The system of claim 19, wherein the pump is sized and configured to discharge blood at volumetric flow rates between about 0.1 liters/min and about 3.0 liters/min. 24. The system of claim 19, wherein the conduit is comprised of a material that is sufficiently flexible so as not to prevent the patient from being ambulatory. 25. The system of claim 19, wherein the pump is configured to be implanted within the patient. 26. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof is substantially below that of the patient's heart when healthy; and a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculature wherein the blood may travel in reverse directions within the conduit; wherein the conduit is comprised of a material that is sufficiently flexible so as not to prevent the patient from being ambulatory, and wherein the pump is configured to be implanted within the patient. 27. The system of claim 26, wherein the conduit comprises a multi-lumen catheter. 28. The system of claim 26, wherein a first location of the patient's vasculature is in a femoral artery and a second location is in the aorta. 29. The system of claim 26, wherein a first location of the patient's vasculature is in a femoral artery and a second location is in an axillary artery. 30. The system of claim 26, wherein the pump is sized and configured to discharge blood at volumetric flow rates between about 0.1 liters/min and about 3.0 liters/min. 31. The system of claim 26, wherein the system is configured to be applied to the patient through a single cannulation site. 32. The system of claim 26, wherein the pump comprises a rotary pump. 33. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof; is substantially below that of the patient's heart when healthy; and a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculature wherein the blood may travel in reverse directions within the conduit; wherein the conduit is comprised of a material that is sufficiently flexible so as not to prevent the patient from being ambulatory, and wherein the pump comprises a rotary pump. 34. The system of claim 33, wherein the conduit comprises a multi-lumen catheter. 35. The system of claim 33, wherein a first location of the patients vasculature is in a femoral artery and a second location is in the aorta. 36. The system of claim 33, wherein a first location of the patient's vasculature is in a femoral artery and a second location is in an axillary artery. 37. The system of claim 33, wherein the pump is sized and configured to discharge blood at volumetric flow rates between about 0.1 liters/min and about 3.0 liters/min. 38. The system of claim 33, wherein the system is configured to be applied to the patient through a single cannulation site. 39. The system of claim 33, wherein the pump is configured to be implanted within the patient. 40. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof; is substantially below that of the patient's heart when healthy; and a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculature wherein the blood may travel in reverse directions within the conduit; wherein the conduit is comprised of a material that is sufficiently flexible so as not to prevent the patient from being ambulatory, and wherein the conduit is configured to direct blood from a first peripheral vessel to a second vessel. 41. The system of claim 40, wherein the lint peripheral vessel is a femoral artery and the second vessel is the aorta. 42. The system of claim 40, wherein the conduit comprises a multi-lumen catheter. 43. The system of claim 40, wherein the pump is sized and configured to discharge blood at volumetric flow rates between about 0.1 liters/min and about 3.0 liters/min. 44. The system of claim 40, wherein the system is configured to be applied to the patient through a single cannulation site. 45. The system of claim 40, wherein the pump comprises a rotary pump. 46. The system of claim 40, wherein the pump is configured to be implanted within the patient. 47. The system of claim 40, wherein the first peripheral vessel is a femoral artery and the second vessel is an axillary artery. 48. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof, is substantially below that of the patient's heart when healthy; and a conduit fluidly coupled to the pump and configured to direct blood between two locations within the patient's vasculature wherein the blood may travel in reverse directions within the conduit; wherein the conduit is comprised of a material that is sufficiently flexible so as not to prevent the patient from being ambulatory, and wherein the conduit comprises a multi-lumen catheter. 49. The system of claim 48, wherein the pump is sized and configured to discharge blood at volumetric flow rates between about 0.1 liters/min and about 3.0 liters/min. 50. The system of claim 48, wherein a first location of the patient's vasculature is in a femoral artery and a second location is in the aorta. 51. The system of claim 48, wherein a first location of the patient's vasculature is in a femoral artery and a second location is in an axillary artery. 52. The system of claim 48, wherein the system is configured to be applied to the patient through a single cannulation site. 53. The system of claim 48, wherein the pump comprises a rotary pump. 54. The system of claim 48, wherein the pump is configured to be implanted within the patient.
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