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Neutralizing human anti-IGFR antibody 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-039/395
출원번호 US-0443466 (2003-05-22)
발명자 / 주소
  • Wang,Yan
  • Greenberg,Robert
  • Presta,Leonard
  • Pachter,Jonathan A.
  • Hailey,Judith
  • Brams,Peter
  • Williams,Denise
  • Srinivasan,Mohan
  • Feingersh,Diane
출원인 / 주소
  • Schering Corporation
인용정보 피인용 횟수 : 55  인용 특허 : 16

초록

초록이 없습니다.

대표청구항

대표청구항이 없습니다.

이 특허에 인용된 특허 (16)

  1. O'Connor Rosemary ; Baserga Renato L., Active survival domains of IGF-IR and methods of use.
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  2. Mukku Venkat R. (Fremont CA), Assay for free IGF-I, IGF-II, and GH levels in body fluids.
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  3. Baserga Renato (Ardmore PA), Cell lines which constitutively express IGF-1 and IGF-1 R.
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  4. Cunningham Brian C. ; Lowman Henry ; Wells James A., Human growth hormone variants having enhanced affinity for human growth hormone receptor at site 1.
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  5. Baserga Renato ; Resnicoff Mariana ; D'Ambrosio Consuelo ; Ferber Andre, Inducing resistance to tumor growth with soluble IGF-1 receptor.
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  6. Clark, Ross G.; Lowman, Henry B.; Robinson, Iain C. A. F., Insulin-like growth factor agonist molecules.
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  7. Bishop Walter R. ; Brassard Diana L. ; Nagabhushan Tattanahalli L., Methods of inducing cancer cell death and tumor regression.
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  8. William M. Pardridge, Non-invasive gene targeting to the brain.
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  9. Prager Diane ; Melmed Shlomo, Polynucleic acid encoding variant insulin-like growth factor I receptor beta subunit and receptor.
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  10. Frackelton, Jr., A. Raymond; Eisen, Herman N.; Ross, Alonzo H., Production and use of monoclonal antibodies to phosphotyrosine-containing proteins.
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  11. Michnick Stephen William Watson,CAX ; Remy Ingrid,CAX, Protein fragment complementation assays for the detection of biological or drug interactions.
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  12. Olsson Lennart ; Naranda Tatjana, Receptor derived peptides as modulators of receptor activity.
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  13. Lennart Olsson ; Tatajna Navrenda, Receptor derived peptides involved in modulation of response to ligand binding.
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  14. Lee, Francis Y., Synergistic methods and compositions for treating cancer.
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  15. Friden Phillip M. ; Starzyk Ruth M. ; Morrison Sherie L. ; Park Eun-Chung ; McGrath John P., Transferrin receptor specific ligand-neuropharmaceutical agent fusion proteins.
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  16. Lonberg Nils ; Kay Robert M., Transgenic non-human animals for producing heterologous antibodies.
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  1. Zauderer, Maurice; Evans, Elizabeth E., Anti-C35 antibody combination therapies and methods.
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  2. Hariharan, Kandasamy; Glaser, Scott; Garber, Ellen; Graff, Christilyn; Reyes, Christopher L.; Demarest, Stephen, Anti-IGF-1R antibodies and uses thereof.
    상세보기
  3. Wang, Yan; Pachter, Jonathan A.; Bishop, Walter Robert, Anti-IGFR1 antibody therapeutic combinations.
    상세보기
  4. Hariharan, Kandasamy; Glaser, Scott; Garber, Ellen; Graff, Christilyn; Reyes, Christopher L.; Demarest, Stephen, Anti-IGR-1R antibodies and uses thereof.
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  5. Loizos, Nick; Huber, Jim, Antibodies against PDGFRa.
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  6. Loizos, Nick; Huber, Jim, Antibodies against PDGFRα to inhibit tumor growth.
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  7. Campbell, Jamie Iain; Cochrane, Duncan James; Finch, Donna Kirsty; Groves, Maria Anastasia Teresa; Lowe, David Christopher; Cruwys, Simon Charles, Antibodies to IL-1 R1 and methods of making them.
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  8. Campbell, Jamie Iain; Cochrane, Duncan James; Finch, Donna Kirsty; Groves, Maria Anastasia Teresa; Lowe, David Christopher; Cruwys, Simon Charles, Antibodies to IL-1R1.
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  9. Wang, Yan; Pachter, Jonathan A.; Wang, Yaolin; Liu, Ming, Biomarkers for pre-selection of patients for anti-IGF1R therapy.
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  10. Sathyanarayanan, Sriram; Winter, Christopher; Klinghoffer, Richard, Compositions and methods for treating cancer.
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  11. Calzone, Frank J.; Deshpande, Rajendra V.; Tsai, Mei-Mei, Compositions and methods relating to anti IGF-1 receptor antibodies.
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  12. Calzone, Frank J.; Deshpande, Rajendra V.; Tsai, Mei-Mei, Compositions and methods relating to anti-IGF-1 receptor antibodies.
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  13. Calzone, Frank J.; Deshpande, Rajendra V.; Tsai, Mei-Mei, Compositions and methods relating to anti-IGF-1 receptor antibodies.
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  14. Calzone, Frank J.; Deshpande, Rajendra V.; Tsai, Mei-Mei, Compositions and methods relating to anti-IGF-1 receptor antibodies.
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  15. Calzone, Frank J.; Deshpande, Rajendra V.; Tsai, Mei-Mei, Compositions and methods relating to anti-IGF-1 receptor antibodies.
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  16. Magneson, Gerald Ross; Orahood, Richard Cushman, Compositions for radiolabeling diethylenetriaminepentaacetic acid (DTPA)-dextran.
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  17. Retallack, Diane M.; Squires, Charles H.; Watkins, David C.; Lee, Stacey L.; Gaertner, Frank H.; Shutter, Robert, Expression of mammalian proteins in Pseudomonas fluorescens.
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  18. Retallack, Diane M.; Squires, Charles H.; Watkins, David C.; Lee, Stacey L.; Gaertner, Frank H.; Shutter, Robert, Expression of mammalian proteins in Pseudomonas fluorescens .
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  19. Retallack, Diane M.; Squires, Charles H.; Watkins, David C.; Lee, Stacey L.; Gaertner, Frank H.; Shutter, Robert, Expression of mammalian proteins in pseudomonas fluorescens.
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  20. Lu, Brian DerHua; Yao, Siu-Long; Seidel-Dugan, Cynthia; Wang, Yan, FDG-pet evaluation of Ewing's sarcoma sensitivity.
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  21. DiPerna, Paul M, Flow regulating stopcocks and related methods.
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  22. Ludwig, Dale L, Fully human antibodies directed against the human insulin-like growth factor-1 receptor.
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  23. Ludwig, Dale L., Fully human antibodies directed against the human insulin-like growth factor-1 receptor.
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  24. Ludwig, Dale L.; Plymate, Stephen R., IGF-IR antagonists as adjuvants for treatment of prostate cancer.
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  25. DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  26. DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  27. Kruse, Geoffrey A., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  28. Michaud, Michael; Kruse, Geoffrey A., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  29. Michaud, Michael; Kruse, Geoffrey A., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  30. Verhoef, Erik T.; DiPerna, Paul M.; Rosinko, Mike; Williamson, Mark; Kruse, Geoffrey A.; Ulrich, Thomas R.; Lamb, Phil; Saint, Sean; Michaud, Michael; Trevaskis, William, Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  31. Saha, Deba P., Mammalian expression vector pUHAB.
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  32. Saha, Deba P., Mammalian expression vector pUHAB.
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  33. Saha, Deba P., Mammalian expression vector pUHAB.
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  34. Ramseier, Thomas M.; Coleman, Russell J.; Schneider, Jane C.; Hershberger, Charles D.; Retallack, Diane M.; Squires, Charles H., Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins.
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  35. Retallack, Diane M.; Squires, Charles H.; Ramseier, Thomas M.; Coleman, Russell J.; Schneider, Jane C.; Hershberger, Charles D., Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins.
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  36. Yao, Siu-Long, Methods for treatment of polyposis.
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  37. Loizos, Nick; Fatatis, Alessandro; Dolloff, Nathan Graeme, Methods of treating secondary bone tumors with antibodies against PDGFR alpha.
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  38. Wang, Yan; Greenberg, Robert; Presta, Leonard; Pachter, Jonathan A.; Hailey, Judith; Brams, Peter; Williams, Denise; Srinivasan, Mohan; Feingersh, Diane, Neutralizing human anti-IGFR antibody.
    상세보기
  39. Wang, Yan; Greenberg, Robert; Presta, Leonard; Pachter, Jonathan A.; Hailey, Judith; Brams, Peter; Williams, Denise; Srinivasan, Mohan; Feingersh, Diane, Neutralizing human anti-IGFR antibody.
    상세보기
  40. Wang, Yan; Greenberg, Robert; Presta, Leonard; Pachter, Jonathan A.; Hailey, Judith; Brams, Peter; Williams, Denise; Srinivasan, Mohan; Feingersh, Diane, Neutralizing human anti-IGFR antibody.
    상세보기
  41. Wang, Yan; Greenberg, Robert; Presta, Leonard; Pachter, Jonathan A.; Hailey, Judith; Brams, Peter; Williams, Denise; Srinivasan, Mohan; Feingersh, Diane, Neutralizing human anti-IGFR antibody.
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  42. Campbell, Jamie Iain; Cochrane, Duncan James; Finch, Donna Kirsty; Groves, Maria Anastasia Teresa; Lowe, David Christopher; Cruwys, Simon Charles, Nucleic acid molecule encoding a specific IL-1R1 antibody.
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  43. Saha, Deba P., Plasmid system for multigene expression.
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  44. Ramseier, Thomas M.; Jin, Hongfan; Squires, Charles H., Process for improved protein expression by strain engineering.
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  45. Ramseier, Thomas M.; Jin, Hongfan; Squires, Charles H., Process for improved protein expression by strain engineering.
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  46. DiPerna, Paul M., Slideable flow metering devices and related methods.
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  47. Brown, David, Solute concentration measurement device and related methods.
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  48. Rosinko, Michael J.; Kruse, Geoffrey A.; Harris, Paul, System and method for detecting occlusions in an infusion pump.
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  49. Metzmaker, Thomas; Saint, Sean; Michaud, Michael; Rosinko, Michael J.; Swanson, Vance, Systems including vial adapter for fluid transfer.
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  50. Varnum, Brian; Vezina, Chris; Witte, Alison; Qian, Xueming; Martin, Francis Hall; Huang, Haichun; Elliot, Gary, Therapeutic human anti-IL-1R1 monoclonal antibody.
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  51. Varnum, Brian; Vezina, Chris; Witte, Alison; Qian, Xueming; Martin, Francis Hall; Huang, Haichun; Elliott, Gary, Therapeutic human anti-IL-1R1 monoclonal antibody.
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  52. Varnum, Brian; Vezina, Chris; Witte, Alison; Qian, Xueming; Martin, Francis Hall; Huang, Haichun; Elliott, Gary, Therapeutic human anti-IL-1R1 monoclonal antibody.
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  53. Varnum, Brian; Vezina, Chris; Witte, Alison; Qian, Xueming; Martin, Francis Hall; Huang, Haichun; Elliott, Gary, Therapeutic human anti-IL-1R1 monoclonal antibody.
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  54. Varnum,Brian; Vezina,Chris; Witte,Alison; Qian,Xueming; Martin,Francis Hall; Huang,Haichun; Elliott,Gary, Therapeutic human anti-IL1-R1 monoclonal antibody.
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  55. DiPerna, Paul M., Two chamber pumps and related methods.
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