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Fatty acid-anticancer conjugates and uses thereof 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/337
  • C07D-305/14
  • C07D-305/00
출원번호 US-0265307 (1999-03-09)
발명자 / 주소
  • Webb,Nigel L.
  • Bradley,Matthews O.
  • Anthony,Forrest
  • Fisher,Mark
출원인 / 주소
  • Luitpold Pharmaceuticals, Inc.,
대리인 / 주소
    Wolf, Greenfield & Sacks, P.C.
인용정보 피인용 횟수 : 15  인용 특허 : 67

초록

초록이 없습니다.

대표청구항

대표청구항이 없습니다.

이 특허에 인용된 특허 (67)

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  6. Hashimoto Atsushi (Tsukuba JPX) Hibino Hidehiko (Tokyo JPX) Nakachi Osamu (Ushiku JPX), Antipsychotic drug.
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  9. Bombardelli Ezio (Milan ITX) Gabetta Bruno (Milan ITX), Baccatine III derivatives.
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  10. Katz Robert ; Tomoaia-Cottsel Maria, Carrier compositions for anti-neoplastic drugs.
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  12. Bradley Matthews O. ; Shashoua Victor E. ; Swindell Charles S. ; Webb Nigel L., Cholinergic compositions and uses thereof.
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  13. Alexander Jose (Lawrence KS) Repta A. J. (Lawrence KS) Fix Joseph A. (Lawrence KS), Chorine esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingua.
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  17. Shashoua Victor E. ; Swindell Charles S. ; Webb Nigel L. ; Bradley Matthews O., DHA-pharmaceutical agent conjugates of taxanes.
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  18. Fisher Abraham (Holon ILX) Levy Drora (Herzeliya B ILX) Spiegelstein Michael Y. (Rehovot ILX) Grunwald Jacob (Rehovot ILX) Levy Aharon (Moshav Beith Hanan ILX) Kushnir Moshe (Nir Zevi ILX), Drug delivery system.
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  22. Bradley Matthews O. ; Shashoua Victor E. ; Swindell Charles S. ; Webb Nigel L., Fatty acid-antipsychotic compositions and uses thereof.
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  23. Shashoua Victor E. (176 Tappan St. Brookline MA 02146), Fatty acid-neuroactive drug conjugate as a prodrug.
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  24. Horrobin David F. (Guildford GB2) McMordie Austin (Carlisle GB2) Manku Mehar S. (Carlisle GB2), Formulations containing unsaturated fatty acids.
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  25. Mayhew Eric (Monmouth Junction NJ) Franklin J. Craig (Princeton NJ) Bhatia Suresh (Alaknanda INX) Harmon Paul A. (Newtown PA) Janoff Andrew S. (Yardley PA), Hydrophobic taxane derivatives.
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  26. Mayhew Eric ; Franklin J. Craig ; Bhatia Suresh,INX ; Harmon Paul A. ; Janoff Andrew S., Hydrophobic taxane derivatives.
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  27. Crozier-Willi Gayle (Evian FRX) Fleith Mathilde (Vevey CHX) Buchanan Michael (Toronto CAX), Inhibition of cell adhesion for reducing cancer cell metastases.
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  28. Freed Ellen (Oakland CA) Ruggieri Rosamaria (San Francisco CA), Interaction of RAF-1 and 14-3-3 proteins.
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  29. Horrobin David F. (Guildford ; Surrey GB2) Begin Michel E. (Nova Scotia CAX), Iron-containing composition and method for treatment of cancer.
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  30. Hausheer Frederick H. (San Antonio TX) Haridas Kochat (San Antonio TX), Lactone stable formulation of 10-hydroxy 7-ethyl camptothecin and methods for uses thereof.
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  31. Hostetler Karl Y. (Del Mar CA) Kumar Raj (San Diego CA), Lipid derivatives of phosphonoacids for liposomal incorporation and method of use.
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  32. Folkers, Karl; Laesecke, Klaus P., Lipoidal biopterin compounds.
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  33. Hostetler Karl Y. (Del Mar CA) Kumar Raj (San Diego CA) Stuhmiller Louise M. (Rancho Santa Fe CA), Liponucleotide-containing liposomes.
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  34. Ansell Steve (Vancouver CAX), Lipophilic drug derivatives for use in liposomes.
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  35. Mark David A. (Oak Park IL) Rowe W. Bruce (Evanston IL), Method and composition for treating immune disorders, inflammation and chronic infections.
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  36. Malfroy-Camine Bernard (Arlington MA), Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier perm.
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  37. Hostetler Karl Y. (Del Mar CA) Kumar Raj (San Diego CA), Method of converting a drug to an orally available form by covalently bonding a lipid to the drug.
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  38. Shashoua Victor E. (Brookline MA) Hesse Gary W. (Winchester MA), Method of treating tardive dyskinesia using dopaminergic agents of prodrugs of therapeutic agents.
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  39. Shashoua Victor E. (Brookline MA), Nerve growth peptides.
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  40. Garleb Keith A. (Powell OH) DeMichele Stephen J. (Dublin OH) Rausch Linda S. (Blacklick OH) Fuller Martha K. (Columbus OH) Behr Stephen R. (Westerville OH), Nutritional product for persons having a neurological injury.
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  41. Murray Christopher K. (Boulder CO) Beckvermit Jeffrey T. (Boulder CO) Ziebarth Timothy D. (Boulder CO), Oxidation products of cephalomannine.
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  42. Horrobin David F. (Guildford GB2), Pharmaceutical compositions containing interferons and fatty acids.
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  43. Mongelli Nicola (Milan ITX) Angelucci Francesco (Milan ITX) Pesenti Enrico (Cologno Monzese ITX) Suarato Antonino (Milan ITX) Biasoli Giovanni (Gavirate ITX), Polymer-bound paclitaxel derivatives.
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  44. Mongelli Nicola (Milan ITX) Angelucci Francesco (Milan ITX) Pesenti Enrico (Cologno Monzese ITX) Suarato Antonino (Milan ITX) Biasoli Giovanni (Gavirate ITX), Polymer-bound paclitaxel derivatives.
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  45. Bayon Yves (Venissieux FRX) Croset Martine (Bron FRX) Lagarde Michel (Chassieu FRX) Lecerf Jean (Genlis FRX) Thies Frank (Dijon FRX) Tayot Jean-Louis (La-Tour-de-Salvagny FRX) Chirouze Veronique (Sai, Polyunsaturated fatty acid based drugs.
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  46. Literati Pter N. (Budapest HUX) Kri Gyrgy (Budapest HUX) Boross Mria (Budapest HUX) Nmeth Gbor (Budapest HUX) Szilbereky Jeno (Budapest HUX) Szilgyi Ildik (Budapest HUX), Polyunsaturated fatty acid derivatives, pharmaceutical compositions containing the same, method for the preparation ther.
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  47. Growdon John H. (Brookline MA) Wurtman Richard J. (Boston MA), Process and composition for treating disorders by administering amphetamine and choline.
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  48. Gaullier Jean-Claude (Champs sur Marne FRX) Mandard Bernadette (Alfortville FRX) Margraff Rodolphe (Viry Chatillon FRX), Process for obtaining 10-deacetylbaccatin III.
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  49. Bourzat Jean-Dominique (Vincennes FRX) Commercon Alain (Vitry sur Seine FRX) Paris Jean-Marc (Vaires sur Marne FRX), Process for preparing taxane derivatives, new derivatives obtained and pharmaceutical compositions containing them.
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  50. Colin Michel (Thoiry FRX) Guenard Daniel (Montrouge FRX) Gueritte-Voegelein Francoise (Paris FRX) Potier Pierre (Paris FRX), Process for the preparation of taxol and 10-deacetyltaxol.
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  51. Hostetler Karl Y. (Del Mar CA) Sridhar Nagarajan C. (Simi Valley CA), Prodrugs for oral administration containing taxol or substituted taxol covalently bound to a phospholipid.
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  52. Kozak Alexander,ILX, Prodrugs with enhanced penetration into cells.
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  53. Kozak Alexander,ILX, Prodrugs with enhanced penetration into cells.
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  54. Kozak Alexander,ILX, Prodrugs with enhanced penetration into cells.
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  55. Kozak Alexander,ILX, Prodrugs with enhanced penetration into cells.
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  56. Bruzzese Tiberio,ITX, Salts of a polyunsaturated fatty acid and pharmaceutical formulations containing them.
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  57. Horrobin David F. (Guildford GB2), Schizophrenia.
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  58. Agharkar Shreeram N. (Fayetteville NY) Gogate Uday S. (East Syracuse NY), Stabilized pharmaceutical composition and stabilizing solvent.
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  59. Bradley Matthews O. ; Shashoua Victor E. ; Swindell Charles S. ; Webb Nigel L., Taxane compounds and compositions.
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  60. Bombardelli Ezio (Milan ITX) Gabetta Bruno (Milan ITX), Taxane derivatives, their preparation and use in oncology.
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  61. Swindell Charles S. ; Shashoua Victor E. ; Bradley Matthews O. ; Webb Nigel L., Taxanes.
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  62. Colin Michel (Thoiry FRX) Guenard Daniel (Montrouge FRX) Gueritte-Voegelein Francoise (Paris FRX) Potier Pierre (Paris FRX), Taxol derivatives, their preparation and pharmaceutical compositions containing them.
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  63. Whittaker Robert George,AUX ; Bender Veronika Judith,AUX ; Reilly Wayne Gerrard,AUX ; Moghaddam Minoo,AUX, Therapeutic compound--fatty acid conjugates.
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  64. Horrobin David F. (Guildford GB2), Treating tardive dyskinesia with essential fatty acid compositions.
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  65. Kingston David G. I. (Blacksburg VA) Zhao Zhi-Yang (Blacksburg VA), Water soluble derivatives of taxol.
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  66. Kingston David G. I. (Blacksburg VA) Zhao Zhi-Yang (Kalamazoo MI), Water soluble derivatives of taxol.
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  67. Vishnuvajjala B. Rao (Rockville MD) Garzon-Aburbeh Aaron (St. Louis Park MN), Water soluble prodrugs of camptothecin.
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이 특허를 인용한 특허 (15)

  1. Webb, Nigel L.; Bradley, Matthews O.; Swindell, Charles S.; Shashoua, Victor E., Fatty acid-pharmaceutical agent conjugates.
    상세보기
  2. Swindell, Charles S.; Fegley, Glenn J., Fatty amine drug conjugates.
    상세보기
  3. DiPerna, Paul M, Flow regulating stopcocks and related methods.
    상세보기
  4. DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  5. DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  6. Kruse, Geoffrey A., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  7. Michaud, Michael; Kruse, Geoffrey A., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  8. Michaud, Michael; Kruse, Geoffrey A., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  9. Verhoef, Erik T.; DiPerna, Paul M.; Rosinko, Mike; Williamson, Mark; Kruse, Geoffrey A.; Ulrich, Thomas R.; Lamb, Phil; Saint, Sean; Michaud, Michael; Trevaskis, William, Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
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  10. Kumar, Samarth; Kane, Prashant; Bhowmick, Balaram Subhas; Ganorkar, Kirti; Patel, Nishit; Dubewar, Anilrao Ashish; Patel, Mukeshbhai Umeshkumar, Perfusion dosage form.
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  11. DiPerna, Paul M., Slideable flow metering devices and related methods.
    상세보기
  12. Brown, David, Solute concentration measurement device and related methods.
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  13. Rosinko, Michael J.; Kruse, Geoffrey A.; Harris, Paul, System and method for detecting occlusions in an infusion pump.
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  14. Metzmaker, Thomas; Saint, Sean; Michaud, Michael; Rosinko, Michael J.; Swanson, Vance, Systems including vial adapter for fluid transfer.
    상세보기
  15. DiPerna, Paul M., Two chamber pumps and related methods.
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