Implantable heart assist system and method of applying same
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-001/12
A61M-001/10
출원번호
US-0878592
(2004-06-28)
등록번호
US-7331921
(2008-02-19)
발명자
/ 주소
Viole,Anthony
Sirimanne,Laksen
Bolling,Steven F.
O'Leary,Shawn
Pecor,Robert
Kelly,Ryan
Werner,Wolfgang
Beizai,Masoud
출원인 / 주소
Orqis Medical Corporation
대리인 / 주소
Knobbe, Martens, Olson & Bear LLP
인용정보
피인용 횟수 :
65인용 특허 :
188
초록▼
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and ou
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart. In another embodiment, the system is positioned extracorporeally, with the inflow conduit and outflow conduit applied percutaneously to a non-primary vessel for circulating blood to and from the non-primary vessel or between the non-primary vessel and another blood vessel within the patient's vasculature.
대표청구항▼
What is claimed is: 1. A method for increasing perfusion through a renal artery, the method comprising: providing fluid communication between a conduit and means for pumping blood; advancing the pumping means to a location within the descending aorta and an outlet of the conduit to a location proxi
What is claimed is: 1. A method for increasing perfusion through a renal artery, the method comprising: providing fluid communication between a conduit and means for pumping blood; advancing the pumping means to a location within the descending aorta and an outlet of the conduit to a location proximate a renal artery; and operating said pumping means to direct blood from the descending aorta to the renal artery at volumetric rates that are on average subcardiac to increase perfusion through the renal artery; wherein advancing further comprises advancing the conduit to a location in the vasculature having a width that is meaningfully larger than the width of the conduit. 2. The method of claim 1, wherein the pumping means further comprises pump driving means and further comprising advancing pump driving means into the vasculature. 3. The method of claim 1, further comprising inserting the pumping means and the conduit into a non-primary vessel subcutaneously in a minimally-invasive procedure. 4. The method of claim 1, further comprising configuring the conduit and pumping means such that blood can flow in the aorta outside the conduit after the conduit is advanced to a location in the aorta. 5. The method of claim 1, wherein blood flows inside the conduit and outside the conduit in the aorta while the pumping means is operating. 6. The method of claim 1, wherein the pumping means comprises an open sided housing that permits blood flow therethrough. 7. The method of claim 1, wherein the pumping means is operated in a pulsatile fashion. 8. The method of claim 1, wherein the pumping means comprises a rotary pump. 9. The method of claim 1, wherein the pumping means comprises an impeller and operating the pumping means comprises rotating the impeller. 10. The method of claim 1, wherein providing fluid communication between a conduit and means for pumping blood comprises positioning the pumping means within the conduit. 11. An intravascular system for increasing perfusion through a renal artery, comprising: means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a transverse dimension that is meaningfully smaller than the transverse dimension of a location in the descending aorta where the conduit is positioned; and wherein the conduit comprises a first lumen in which at least a portion of the pumping means is housed and a second lumen adjacent and parallel to the first lumen. 12. A method for increasing perfusion through a renal artery, the method comprising: providing fluid communication between a conduit and means for pumping blood; advancing the pumping means to a location within the descending aorta and an outlet of the conduit to a location proximate a renal artery; and operating said pumping means to direct blood from the descending aorta to the renal artery at volumetric rates that are on average subcardiac to increase perfusion through the renal artery; wherein the conduit has a first width and advancing comprises advancing the conduit to a location within the vasculature having a second width, the first width being less than about one-half the second width. 13. A method for increasing perfusion through a renal artery, the method comprising: providing fluid communication between a conduit and means for pumping blood; advancing the pumping means to a location within the descending aorta and an outlet of the conduit to a location proximate a renal artery; operating said pumping means to direct blood from the descending aorta to the renal artery at volumetric rates that are on average subcardiac to increase perfusion through the renal artery; and providing a blood flow path in a side lumen of the conduit adjacent the pumping means. 14. An intravascular system for increasing perfusion through a renal artery, comprising: means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a first cross-sectional area and a location in the descending aorta where the conduit is positioned has a second cross-sectional area, the first cross-sectional area being less than about one-half the second cross-sectional area; and wherein the pumping means further comprises pump driving means configured to be advanced into the patient's vasculature. 15. The pumping system of claim 14, wherein the conduit comprises an inlet and an outlet, the conduit configured such that when the system is applied within the vasculature the inlet can be positioned at a first location in the descending aorta and the outlet can be positioned at a second location in the descending aorta below the first location. 16. The pumping system of claim 14, further comprising an open sided housing that permits blood flow therethrough and that houses at least a portion of the pumping means. 17. The pumping system of claim 14, wherein the conduit comprises an inlet and an outlet, the conduit configured such that when the system is applied within the vasculature the inlet can be positioned at a first location in the descending aorta and the outlet can be positioned at a second location in the descending aorta downstream of the first location. 18. An intravascular system for increasing perfusion through a renal artery, comprising: means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a first cross-sectional area and a location in the descending aorta where the conduit is positioned has a second cross-sectional area, the first cross-sectional area being less than about one-half the second cross-sectional area; and wherein the conduit comprises a first lumen in which at least a portion of the pumping means is housed and a second lumen for conveying blood adjacent to the first lumen. 19. The pumping system of claim 18, wherein the pumping means further comprises pump driving means configured to be advanced into the patient's vasculature. 20. An intravascular system for increasing perfusion through a renal artery, comprising: means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a first cross-sectional area and a location in the descending aorta where the conduit is positioned has a second cross-sectional area, the first cross-sectional area being less than about one-half the second cross-sectional area; and wherein the conduit comprises an inlet and an outlet, the conduit configured such that when the system is applied within the vasculature the inlet can be positioned at a first location in the descending aorta and the outlet can be positioned at a second location in the descending aorta upstream of the first location. 21. An intravascular system for increasing perfusion through a renal artery, comprising: means for pumping blood; and a conduit fluidly coupled with the pumping means and configured to direct blood in the descending aorta toward a renal artery to maintain or enhance blood flow to a kidney supplied by the renal artery; whereby the pumping means and the conduit are configured to be insertable into a non-primary vessel subcutaneously in a minimally-invasive procedure; wherein the conduit has a transverse dimension that is meaningfully smaller than the transverse dimension of a location in the descending aorta where the conduit is positioned; and wherein the conduit comprises an inlet and an outlet, the conduit configured such that when the system is applied within the vasculature the inlet can be positioned at a first location in the descending aorta and the outlet can be positioned at a second location in the descending aorta upstream of the first location. 22. The pumping system of claim 21, wherein the conduit comprises an inlet and an outlet, wherein the pump is positioned at least partially within the conduit at a location between the inlet and the outlet, and wherein the conduit is configured to permit significant flow around the conduit at least from the inlet to the pump. 23. The pumping system of claim 21, wherein the conduit comprises an inlet and an outlet, wherein the pump is positioned at least partially within the conduit at a location between the inlet and the outlet, and wherein the conduit is configured to permit significant flow around the conduit at least from the pump to the outlet. 24. The pumping system of claim 21, wherein the conduit comprises an inlet and an outlet, wherein the pump is positioned at least partially within the conduit at a location between the inlet and the outlet, and wherein the conduit is configured to permit significant flow around the conduit from the inlet to the outlet.
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이 특허에 인용된 특허 (188)
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