Medical injector and medicament loading system for use therewith
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-005/00
출원번호
US-0743436
(2003-12-23)
등록번호
US-7341575
(2008-03-11)
발명자
/ 주소
Rice,Mark W.
Lesch, Jr.,Paul R.
Nelson,Sheldon J.
Byland,Timothy D.
출원인 / 주소
Antares Pharma, Inc.
대리인 / 주소
Winston & Strawn LLP
인용정보
피인용 횟수 :
26인용 특허 :
38
초록▼
The present invention discloses a medical injector and medicament loading system for use therewith. The medicament loading system includes cap for a medicament cartridge. The cap has a post for causing movement of the cartridge stopper toward the seal when the cap engages the medicament cartridge to
The present invention discloses a medical injector and medicament loading system for use therewith. The medicament loading system includes cap for a medicament cartridge. The cap has a post for causing movement of the cartridge stopper toward the seal when the cap engages the medicament cartridge to thereby eliminate adhesion between the medicament chamber and the stopper. The medical injector according to the present invention includes the medicament loading system, i.e., a cartridge assembly, a needle free syringe assembly, and a power pack assembly.
대표청구항▼
What is claimed is: 1. An injection device, comprising: an injector filling assembly, comprising: a cartridge housing configured for receiving a cartridge that has a chamber containing a medicament and first and second ends, the first end including a seal for sealing the medicament in the chamber,
What is claimed is: 1. An injection device, comprising: an injector filling assembly, comprising: a cartridge housing configured for receiving a cartridge that has a chamber containing a medicament and first and second ends, the first end including a seal for sealing the medicament in the chamber, and the second end including a stopper sealingly disposed in the chamber; an adapter associated with the cartridge housing and configured for coupling the chamber to an injector for transferring the medicament to the injector for loading the injector; and a post associated with the cartridge housing such that the post is too short to load the injector by biasing the stopper with the post, but is sufficiently long to displace the stopper towards the seal by an amount sufficient to overcome any adhesion between the chamber and the stopper for permitting filling of the injector by drawing the medicament from the chamber by vacuum; and a needle free injector comprising: a needle free syringe assembly comprising: a nozzle member defining a fluid chamber and having a proximal end configured and dimensioned for mating with the second side of the adapter and a distal end, and a plunger movable in the fluid chamber; and a power pack assembly comprising: a housing having a proximal end connectable with the distal end of the nozzle member and a distal end; a trigger assembly; and an energy source operatively associated with the trigger assembly so that movement of the trigger assembly activates the energy source to move the plunger in a first direction to expel medicament from the fluid chamber when the adapter is not connected to the needle free syringe assembly and movement of the plunger in a second direction draws medicament out of the cartridge chamber and into the fluid chamber when the adapter is connected to the needle free syringe assembly. 2. The injection device of claim 1, wherein the filling assembly further comprises the cartridge. 3. The injection device of claim 2, wherein the medicament chamber comprises a first chamber containing a lyophilized medicament, a second chamber containing a reconstituting fluid, a dividing member separating the first and second chambers, and a bypass channel for providing fluid communication between the first and second chambers upon movement of the dividing member, wherein fluid pressure generated by movement of the stopper causes movement of the dividing member. 4. The injection device of claim 1, wherein the injector and filling assembly comprise threaded portions configured for connecting to each other. 5. A method of filling the injection device of claim 1, comprising: associating the adapter with the cartridge to associate the chamber with the injector; associating the adapter with the injector; displacing the stopper within the chamber with the post; and transferring the medicament to the injector from the chamber by providing aspiration from the injector. 6. The injection device of claim 1, wherein the post is associated with the cartridge housing such that movement of the post towards the first end is limited to limit the displacement of the stopper by the post for permitting the majority of the medicament to be drawn out of the chamber by vacuum. 7. The injection device of claim 1, wherein the post is associated with the cartridge housing such that the post is prevented from moving past a post position to prevent the post from further displacing the stopper towards the seal to require loading the injector by drawing the medicament from the chamber by vacuum. 8. The injection device of claim 7, wherein the post in the post position is prevented from further displacing the stopper towards the seal so that the majority of the medicament must be drawn out of the chamber by vacuum. 9. The injection device of claim 1, wherein the post is associated with the housing such that the post is prevented from displacing the stopper towards the seal by distance sufficient to expel a substantial amount of the medicament from the chamber when the seal is open. 10. The injection device of claim 1, wherein the assembly further comprises a cap to which the post is mounted, the cap being engageable with the cartridge housing on a side of the housing opposite from the adapter to limit displacement of the stopper towards by the post. 11. The injection device of claim 10, wherein the cap is engageable with the housing such that upon said engagement the post is moved against the stopper to displace the stopper sufficiently to overcome the adhesion. 12. The injection device of claims 11, wherein the cap and housing comprise threads that are engageable by rotating the cap to limit the displacement of the stopper towards the seal by the post. 13. The injection device of claim 12, wherein the threads are associated to move the post to displace the stopper upon the rotation of the cap to overcome the adhesion. 14. The injection device of claim 1, wherein the post is sufficiently short so that the displacement of the stopper is only sufficiently long to substantially purge the air contained in the medicament cartridge prior to the attachment to the injector. 15. The injection device of claim 1, wherein the housing and post are associated to limit movement of the post into the cartridge to require the medicament in the chamber of the medicament cartridge to be drawn out of the chamber into the injector by vacuum. 16. The injection device of claim 1, wherein post has an association fixed with the housing to require the medicament in the chamber of the medicament cartridge to be drawn out of the chamber into the injector by vacuum. 17. The injection device of claim 1, wherein the post is associated with the housing to abut the stopper for causing the displacement thereof. 18. The injection device of claim 1, wherein the adapter is configured for opening the seal to permit extraction of the medicament therefrom. 19. The injection device of claim 1, wherein the adapter comprises at least one resilient retaining member configured for locking the medicament cartridge to adapter and configured for breaking upon removal of the medicament cartridge from the adapter for inhibiting repeat uses with multiple medicament cartridges. 20. The injection device of claim 1, wherein the adapter is of separate construction from the housing.
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