초록 ▼

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and men

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, methyl salicylate, eucalyptol and menthol. The edible films are effective at killing the plaque-producing germs that cause dental plaque, gingivitis and bad breath. The film can also contain pharmaceutically active agents. Methods for producing the films are also disclosed.

대표청구항 ▼

What is claimed is: 1. A consumable film adapted to rapidly dissolve in the mouth of a consumer, wherein said film comprises a single layer including pullulan, from about 0.1% to about 2 wt % of a stabilizing agent comprising a mixture of xanthan gum, locust bean gum and carrageenan and at least on

What is claimed is: 1. A consumable film adapted to rapidly dissolve in the mouth of a consumer, wherein said film comprises a single layer including pullulan, from about 0.1% to about 2 wt % of a stabilizing agent comprising a mixture of xanthan gum, locust bean gum and carrageenan and at least one pharmaceutical agent, wherein said pharmaceutical agent is selected from the group consisting of non-steroidal anti-inflammatory agents, antitussives, decongestants, anti-histamines, expectorants, anti-diarrheals, H2-antagonists, proton pump inhibitors, central nervous system agents, analgesics and mixtures thereof. 2. The consumable film according to claim 1, wherein the non-steroidal anti-inflammatory agent is selected from the group consisting of aspirin, acetaminophen ibuprofen, diflunisal, fenoprofen calcium, naproxen, tolmetin sodium, indomethacin, and mixtures thereof. 3. The consumable film according to claim 1, wherein the anti-tussive is selected from the group consisting of benzonatate, caramiphen edisylate, dextromethorphan hydrobromide, chlophedianol hydrochloride and mixtures thereof. 4. The consumable film according to claim 1, wherein the decongestant is selected from the group consisting of pseudoephedrine hydrochloride, phenylepherine, phenylpropanolamnine and mixtures thereof. 5. The consumable film according to claim 1 wherein the anti-histamine is selected from the group consisting of brompheniramine maleate, chlorpheniramine maleate, carbinoxamine maleare, clemastine fumarate, dexchlorpheniramine maleate, diphenhydramine hydrochloride, diphenhydramine citrate, diphenylpyraline hydrochloride, doxylamine succinate, promethazine hydrochloride, pyrilamine maleate tripelennamine citrate, triprolidine hydrochloride and mixtures thereof. 6. The consumable film according to claim 1, wherein the expectorant is selected from the group consisting of guaifenesin, ipecac, potassium iodide, terpin hydrate and mixtures thereof. 7. The consumable film according to claim 1, wherein the anti-diarrheal is loperamide. 8. The consumable film according to claim 1 wherein the H2-antagonist is selected from the group consisting of famotidine, ranitidine and mixtures thereof. 9. The consumable film according to claim 1, wherein the proton pump inhibitor is selected from the group consisting of omeprazole, lansoprazole, and mixtures thereof. 10. A consumable film adapted to rapidly dissolve in the mouth of a consumer, wherein said film comprises a single layer including pullulan, from about 0.1% to about 2 wt % of a stabilizing agent comprising a mixture of xanthan gum, locust bean gum and carrageenan and at least one pharmaceutical agent, wherein said pharmaceutical agent comprises dextromethorphan. 11. The consumable film of claim 10 wherein said dextromethorphan is in the salt form of dextromethorphan hydrochloride. 12. The consumable film of claim 11 wherein said dextromethorphan hydrochloride is an amount from about 10 mg to about 20 mg. 13. A consumable film adapted to rapidly dissolve in the mouth of a consumer, wherein said film comprises a single layer including pullulan, from about 0.1% to about 2 wt % of a stabilizing agent comprising a mixture of xanthan gum, locust bean gum and carrageenan and at least one pharmaceutical agent, wherein said pharmaceutical agent is selected from the group consisting of famotidine, phenylephrine and mixtures thereof. 14. The consumable film of claim 13 wherein said pharmaceutical agent is famotidine and is present in an amount of about 10 mg. 15. The consumable film of claim 13 wherein said pharmaceutical agent is phenylephrine and is present in the salt form of phenylephrine hydrochloride. 16. The consumable film of claim 15 wherein said phenylephrine hydrochloride is an amount of about 10 mg.