초록 ▼

A multi-well assembly (10) comprises a multi-well block (12) and a guide plate (14). The multi-well block (12) has a plurality of wells (18) each with a fluid-impermeable bottom surface (22). The guide plate (14) has a plurality of fluid passageways (34) corresponding to the wells (18) of the multi-

A multi-well assembly (10) comprises a multi-well block (12) and a guide plate (14). The multi-well block (12) has a plurality of wells (18) each with a fluid-impermeable bottom surface (22). The guide plate (14) has a plurality of fluid passageways (34) corresponding to the wells (18) of the multi-well block (12). The guide plate (14) is configured to establish fluid communication between each well (18) and an associated fluid passageway (34) when the guide plate (14) is aligned with the multi-well block (12).

대표청구항 ▼

We claim: 1. A method of carrying out multiple chemical reactions, the method comprising: providing a multi-well device comprising a plurality of wells having fluid-impervious bottom surfaces; providing a guide plate defining a plurality of passageways corresponding to the wells; introducing reagen

We claim: 1. A method of carrying out multiple chemical reactions, the method comprising: providing a multi-well device comprising a plurality of wells having fluid-impervious bottom surfaces; providing a guide plate defining a plurality of passageways corresponding to the wells; introducing reagents into the wells to initiate respective chemical reactions in the wells; and registering the guide plate with the multi-well device so that each well is in flow-through communication with a respective passageway to permit products of the respective chemical reactions to flow through the passageways, wherein the guide plate has a plurality of upwardly extending projections that open the fluid-impervious bottom surfaces of the plurality of wells whenever the guide plate is registered with the multi-well device, and wherein registering the guide plate with the multi-well device comprises pressing the guide plate and the multi-well device together using a pressing apparatus. 2. The method of claim 1, further comprising registering a multi-well receptacle plate comprising a plurality of wells with the guide plate to collect the products of the chemical reactions flowing from the passageways. 3. The method of claim 1, further comprising providing respective filters in the wells for filtering the reagents. 4. The method of claim 1, further comprising creating a pressure differential across the passageways to facilitate the flow of the respective products of the respective chemical reactions through the passageways.