IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0868109
(2004-06-15)
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등록번호 |
US-7435262
(2008-10-14)
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발명자
/ 주소 |
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출원인 / 주소 |
|
대리인 / 주소 |
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인용정보 |
피인용 횟수 :
89 인용 특허 :
112 |
초록
▼
An interbody spinal implant made of cortical bone or a bone composite adapted for placement across an intervertebral space formed across the height of a disc space between two adjacent vertebral bodies. The implant has a leading end that includes at least a portion of an arc of a circle from side t
An interbody spinal implant made of cortical bone or a bone composite adapted for placement across an intervertebral space formed across the height of a disc space between two adjacent vertebral bodies. The implant has a leading end that includes at least a portion of an arc of a circle from side to side, and sides that are at least in part straight or a trailing end having a radius of curvature of another circle from side to side.
대표청구항
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What is claimed is: 1. An interbody spinal implant made of cortical bone for insertion at least in part into an implantation space formed across the height of a disc space between adjacent vertebral bodies of a human spine, the vertebral bodies having an anterior aspect and a posterior aspect and a
What is claimed is: 1. An interbody spinal implant made of cortical bone for insertion at least in part into an implantation space formed across the height of a disc space between adjacent vertebral bodies of a human spine, the vertebral bodies having an anterior aspect and a posterior aspect and a depth therebetween, said implant comprising: a leading end for insertion first into the disc space, a trailing end opposite said leading end, and opposite sides between said leading end and said trailing end; opposed upper and lower portions between said leading and trailing ends adapted to be placed at least in part within and across the height of the disc space to contact and support the adjacent vertebral bodies, said upper and lower portions being non-arcuate along at least a portion of the length of said implant; and a length from said leading end to said trailing end and a maximum width transverse to the length and across said opposite sides, said maximum width of said implant ranging from about 30 millimeters to about 38 millimeters, said leading end forming one half of a circle from one of said opposite sides to the other of said opposite sides, the circle having a diameter equal to the maximum width of said implant, the length of said implant being greater than the maximum width of said implant. 2. The implant of claim 1, wherein at least a portion of said leading end has a reduced height to facilitate insertion of said implant between the two adjacent vertebral bodies. 3. The implant of claim 1, wherein said trailing end is adapted to conform from side to side to at least a portion of the peripheral contour of at least one of the anterior and posterior aspects of the vertebral bodies adjacent a disc space into which said implant is inserted. 4. The implant of claim 1, wherein said upper and lower portions of said implant include at least one opening in communication with one another to form at least a portion of a passage for permitting for the growth of bone from adjacent vertebral body to adjacent vertebral body through said passage. 5. The implant of claim 4, wherein said implant has a perimeter, said passage being within said perimeter of said implant. 6. The implant of claim 4, wherein said passage is between said leading and trailing ends of said implant. 7. The implant of claim 1, wherein at least one of said opposite sides is at least in part straight along at least a portion of the length of said implant. 8. The implant of claim 1, wherein said implant has a mid-longitudinal axis along the length, at least one of said opposite sides being at least in part oriented generally parallel to the mid-longitudinal axis of said implant. 9. The implant of claim 1, wherein said opposite sides are at least in part generally parallel one another. 10. The implant of claim 1, wherein said maximum width of said implant is greater than one-half of the width of the adjacent vertebral bodies into which said implant is adapted to be inserted. 11. The implant of claim 1, further comprising a curved transition between at least one of said opposite sides and said trailing end, said curved transition forming at least part of an arc of a circle. 12. The implant of claim 1, wherein said implant has a height from said upper portion to said lower portion, the height of said implant being less than the maximum width of said implant. 13. The implant of claim 1, wherein at least a portion of said upper and lower portions are in an angular relationship to each other from trailing end to leading end for allowing angulation of the adjacent vertebral bodies relative to each other. 14. The implant of claim 1, wherein said implant has a maximum length less than and approximating the posterior to anterior depth of the vertebral bodies. 15. The implant of claim 1, further comprising a bone engaging surface formed on the exterior of at least said upper and lower portions for engaging the adjacent vertebral bodies, said bone engaging surface selected from the group consisting of a protrusion, a ratchet, a spike, a spline, surface roughenings, and knurling. 16. The implant of claim 1, wherein said implant includes at least two members, each member having a leading portion, a trailing portion, a top, a bottom, and at least one side, each member being adapted to be placed side by side with another of said members, said leading portion of said members forming said leading end of said implant when placed side by side. 17. The implant of claim 16, wherein said implant includes two of said members, each member being a mirror image of the other. 18. The implant of claim 16, wherein said upper and lower portions of said implant include at least one opening in communication with one another to form at least a portion of a passage for permitting for the growth of bone from adjacent vertebral body to adjacent vertebral body through said passage, each member including at least a portion of said passage. 19. The implant of claim 1, wherein said implant comprises at least in part of a bone growth promoting material. 20. The implant of claim 19, wherein said bone growth promoting material is selected from the group consisting of bone derived products, demineralized bone matrix, mineralizing proteins, ossifying proteins, bone morphogenetic protein, hydroxyapatite, and genes coding for the production of bone. 21. The implant of claim 1, in combination with a bone growth promoting material. 22. The implant of claim 21, wherein said bone growth promoting material is selected from the group consisting of bone derived products, demineralized bone matrix, mineralizing proteins, ossifying proteins, bone morphogenetic protein, hydroxyapatite, and genes coding for the production of bone. 23. The implant of claim 1, wherein said implant is treated with a bone growth promoting substance. 24. The implant of claim 1, wherein said implant is at least in part resorbable. 25. The implant of claim 1, in combination with a chemical substance adapted to inhibit scar formation. 26. The implant of claim 1, in combination with an antimicrobial material. 27. The implant of claim 1, wherein at least a portion of said implant is treated to promote bone ingrowth between said implant and said adjacent vertebral bodies. 28. The implant of claim 1, further in combination with at least one spinal fixation implant. 29. The implant of claim 1, wherein said trailing end is adapted to receive at least one bone screw adapted to engage at least one vertebral body when inserted through said implant. 30. The implant of claim 29, further comprising a lock for locking at least one bone screw to said implant. 31. The implant of claim 30, wherein said lock is made of one of cortical bone and a bioresorbable material. 32. The implant of claim 30, wherein said lock is adapted to lock at least two bone screws to said implant. 33. The implant of claim 30, wherein said lock is adapted to cooperatively engage at least a portion of said trailing end. 34. The implant of claim 29, wherein said screw is made of one of cortical bone and a bioresorbable material. 35. The implant of claim 1, wherein said implant is manufactured from a bone ring obtained from a major long bone of a human having a medullary canal. 36. The implant of claim 1, wherein said implant is manufactured from a bone composite material. 37. The implant of claim 1, wherein said length of said implant ranges from about 28 millimeters to about 36 millimeters. 38. An interbody spinal implant made of cortical bone for insertion at least in part into an implantation space formed across the height of a disc space between adjacent vertebral bodies of a human spine, the vertebral bodies having an anterior aspect and a posterior aspect and a depth therebetween, said implant comprising: a leading end for insertion first into the disc space, a trailing end opposite said leading end, and opposite sides between said leading end and said trailing end; opposed upper and lower portions between said leading and trailing ends adapted to be placed at least in part within and across the height of the disc space to contact and support the adjacent vertebral bodies, said upper and lower portions being non-arcuate along at least a portion of the length of said implant; and a length from said leading end to said trailing end and a maximum width transverse to the length and across said opposite sides, said length of said implant ranging from about 28 millimeters to about 36 millimeters, said leading end forming one half of a circle from one of said opposite sides to the other of said opposite sides, the circle having a diameter equal to the maximum width of said implant, the length of said implant being greater than the maximum width of said implant. 39. The implant of claim 38, wherein said upper and lower portions of said implant include at least one opening in communication with one another to form at least a portion of a passage for permitting for the growth of bone from adjacent vertebral body to adjacent vertebral body through said passage. 40. The implant of claim 38, wherein said implant has a height from said upper portion to said lower portion, the height of said implant being less than the maximum width of said implant. 41. The implant of claim 38, wherein at least a portion of said upper and lower portions are in an angular relationship to each other from trailing end to leading end for allowing angulation of the adjacent vertebral bodies relative to each other. 42. The implant of claim 38, further comprising a bone engaging surface formed on the exterior of at least said upper and lower portions for engaging the adjacent vertebral bodies, said bone engaging surface selected from the group consisting of a protrusion, a ratchet, a spike, a spline, surface roughenings, and knurling. 43. The implant of claim 38, wherein said implant comprises at least in part of a bone growth promoting material. 44. The implant of claim 38, in combination with a bone growth promoting material. 45. The implant of claim 38, wherein said trailing end is adapted to receive at least one bone screw adapted to engage at least one vertebral body when inserted through said implant. 46. The implant of claim 45, further comprising a lock for locking at least one bone screw to said implant. 47. The implant of claim 38, wherein said implant is manufactured from a bone ring obtained from a major long bone of a human having a medullary canal. 48. The implant of claim 38, wherein said implant is manufactured from a bone composite material. 49. An interbody spinal implant made of cortical bone for insertion at least in part into an implantation space formed across the height of a disc space between adjacent vertebral bodies of a human spine, the vertebral bodies having an anterior aspect and a posterior aspect and a depth therebetween, said implant comprising: a leading end for insertion first into the disc space, a trailing end opposite said leading end, and opposite sides between said leading end and said trailing end, said trailing end being adapted to receive at least one bone screw adapted to engage at least one vertebral body when inserted through said implant; a lock for locking at least one bone screw to said implant; opposed upper and lower portions between said leading and trailing ends adapted to be placed at least in part within and across the height of the disc space to contact and support the adjacent vertebral bodies, said upper and lower portions being non-arcuate along at least a portion of the length of said implant; and a length from said leading end to said trailing end and a maximum width transverse to the length and across said opposite sides, said leading end forming one half of a circle from one of said opposite sides to the other of said opposite sides, the circle having a diameter equal to the maximum width of said implant, the length of said implant being greater than the maximum width of said implant. 50. The implant of claim 49, wherein said lock is made of one of cortical bone and a bioresorbable material. 51. The implant of claim 49, wherein said lock is adapted to lock at least two bone screws to said implant. 52. The implant of claim 49, wherein said lock is adapted to cooperatively engage at least a portion of said trailing end. 53. The implant of claim 49, wherein said upper and lower portions of said implant include at least one opening in communication with one another to form at least a portion of a passage for permitting for the growth of bone from adjacent vertebral body to adjacent vertebral body through said passage. 54. The implant of claim 49, wherein said implant has a height from said upper portion to said lower portion, the height of said implant being less than the maximum width of said implant. 55. The implant of claim 49, wherein at least a portion of said upper and lower portions are in an angular relationship to each other from trailing end to leading end for allowing angulation of the adjacent vertebral bodies relative to each other. 56. The implant of claim 49, further comprising a bone engaging surface formed on the exterior of at least said upper and lower portions for engaging the adjacent vertebral bodies, said bone engaging surface selected from the group consisting of a protrusion, a ratchet, a spike, a spline, surface roughenings, and knurling. 57. The implant of claim 49, wherein said implant comprises at least in part of a bone growth promoting material. 58. The implant of claim 49, in combination with a bone growth promoting material. 59. The implant of claim 49, wherein said implant is manufactured from a bone ring obtained from a major long bone of a human having a medullary canal. 60. The implant of claim 49, wherein said implant is manufactured from a bone composite material.
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