Method for forming a laminate assembly with an ultrasonic welder
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B65B-051/22
B29C-065/08
출원번호
US-0508396
(2003-03-25)
등록번호
US-7448184
(2008-11-11)
국제출원번호
PCT/US03/009050
(2003-03-25)
§371/§102 date
20040921
(20040921)
국제공개번호
WO03/095332
(2003-11-20)
발명자
/ 주소
Clark,Verna Lo
Van Oort,Michael Mary
Walker,Richard Ian
출원인 / 주소
Glaxo Group Limited
대리인 / 주소
Riek,James P.
인용정보
피인용 횟수 :
13인용 특허 :
36
초록▼
A laminate assembly, comprising a base sheet having at least one blister formed therein, a pharmaceutical composition displaced in the blister, a lid sheet bonded to the base sheet to form a primary seal therebetween, thus forming a primarily sealed laminate assembly; the primary sealed laminate ass
A laminate assembly, comprising a base sheet having at least one blister formed therein, a pharmaceutical composition displaced in the blister, a lid sheet bonded to the base sheet to form a primary seal therebetween, thus forming a primarily sealed laminate assembly; the primary sealed laminate assembly having a secondary seal formed therein, and related manufacturing method and system of manufacture.
대표청구항▼
What is claimed is: 1. A method for forming a laminate assembly, comprising the steps of: a. providing a base sheet and a lid sheet, said base sheet having formed therein a blister pocket containing a pharmaceutical composition and comprising a first mating surface; said lid sheet comprising a seco
What is claimed is: 1. A method for forming a laminate assembly, comprising the steps of: a. providing a base sheet and a lid sheet, said base sheet having formed therein a blister pocket containing a pharmaceutical composition and comprising a first mating surface; said lid sheet comprising a second mating surface, said base and lid sheets having a primary seal formed between said first and second mating surfaces to form a primarily sealed laminate assembly; b. exposing a portion of said primary sealed laminate assembly to a bonding device to create a secondary seal therein; wherein said bonding device is an ultrasonic welder, said ultrasonic welder comprising a welding sonotrode and an anvil, and said primary sealed laminate assembly is positioned therebetween to form said laminate structure, wherein said anvil comprises at least one rotary anvil defining an annular edge, and said avil comprises an axle having an axis of rotation and a pair of rotary anvils; a first rotary anvil having a first side extending generally tangentially from said axis of rotation and having a first annular edge; and a second rotary anvil having a second side extending generally tangentially from said axis of rotation and having a second annular edge; said first and second rotary anvils being spaced from each other, at least a portion of said first and second annular edges contacting said laminate structure during the creation of said secondary seal. 2. The method of claim 1, wherein at least one of said first or said second annular edges is substantially flat in cross-view. 3. The method of claim 1, wherein at least one of said first or said second annular edges is angled in cross-view. 4. The method of claim 1, wherein at least one of said first or said second annular edges is curved in cross-view. 5. The method of claim 1, further comprising the step of removing a portion of said primarily sealed laminate assembly before, during or after secondary sealing. 6. The method of claim 5, wherein said step of removing a portion of said primarily sealed laminate assembly occurs substantially simultaneously with the creation of said secondary seal. 7. The method of claim 5, wherein said step of removing a portion of said primarily sealed laminate assembly occurs as a result of mechanical cutting. 8. The method of claim 5, wherein said step of removing a portion of said primarily sealed laminate assembly is achieved with an ultrasonic welder. 9. The method of claim 5, wherein said base sheet comprises a base metal layer, and said lid sheet comprises a lid metal layer, said base and lid metal layers are at least partially fused to each other during creation of said secondary seal. 10. The method of claim 1, wherein said base sheet comprises a base metal layer, and said lid sheet comprises a lid metal layer, said base and lid metal layers are at least partially coupled during creation of said secondary seal. 11. The method of claim 1, wherein said base sheet includes at least a first bonding material disposed on said first mating surface and said lid sheet includes at least a second bonding material disposed on said second mating surface. 12. The method of claim 11, wherein said first bonding material comprises at least one polymeric material. 13. The method of claim 12, wherein said first bonding material comprises polyvinyl chloride. 14. The method of claim 11, wherein said first bonding material comprises heat seal lacquer. 15. The method of claim 11, wherein said second bonding material comprises at least one polymeric material. 16. The method of claim 15, wherein said second bonding material comprises polyvinyl chloride. 17. The method of claim 11, wherein said second bonding material comprises heat seal lacquer. 18. The method of claim 1, wherein said first mating surface comprises aluminum. 19. The method of claim 1, wherein said laminate assembly is substantially elongate. 20. The method of claim 19, wherein said laminate assembly comprises a plurality of blisters positioned along the length of the elongate laminate assembly, and wherein said blister has a periphery, and said laminate assembly defines an edge, and a first edge region is defined between the edge and the closest point along the periphery thereto, and said secondary seal extends substantially continuously within said first edge region along a length of said elongated laminate assembly. 21. The method of claim 1, wherein said laminate assembly is substantially circular. 22. A method of claim 1, wherein said primary seal comprises a cross-checked pattern of bonded regions separating non-bonded regions, and said secondary seal is substantially continuous and overlies a portion of the primary seal. 23. The method of claim 1, wherein said base sheet has a first structural material having a first material edge, and said lid sheet has a second structural material having a second material edge, and formation of said secondary seal results in the coupling of a portion of said first and second structural materials at said first and second material edges. 24. A method for forming a laminate assembly, comprising the steps of: a. providing a base sheet and a lid sheet, said base sheet having formed therein a blister pocket containing a pharmaceutical composition and comprising a first mating surface; said lid sheet comprising a second mating surface, said base and lid sheets having a primary seal formed between said first and second mating surfaces to form a primarily sealed laminate assembly, b. exposing a portion of said primary sealed laminate assembly to a bonding device to create a secondary seal therein, wherein said base sheet comprises a base metal layer, and said lid sheet comprises a lid metal layer, and said base and lid metal layers are at a first distance from each other in the region of said primary seal, and at a second distance from each other in the region of said secondary seal, and said first distance is greater than said second distance. 25. The method of claim 24, wherein said laminate assembly has a thickness, and the thickness of said laminate assembly is greater in the region of the primary seal than in the region of the secondary seal.
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