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Use of multiple antioxidant micronutrients as systemic biological radioprotective agents against potential ionizing radiation risks 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/714
  • A61K-031/7135
  • A61K-031/59
  • A61K-031/555
  • A61K-031/525
  • A61K-031/519
  • A61K-031/51
  • A61K-031/506
  • A61K-031/4184
  • A61K-031/4164
  • A61K-031/015
  • A61K-031/01
출원번호 US-0229274 (2002-08-28)
등록번호 US-7449451 (2008-11-11)
발명자 / 주소
  • Prasad,Kedar N.
  • Haase,Gerald M.
  • Cole,William C.
출원인 / 주소
  • Premier Micronutrient Corporation
대리인 / 주소
    DeLaRosa,Dan M.
인용정보 피인용 횟수 : 17  인용 특허 : 53

초록

Disclosed herein is a method for protecting humans in need of such protection from physical damage caused by ionizing radiation comprising administering to said humans on a defined basis prior to and after exposure to such radiation a plurality of antioxidants at a dosage level directly proportional

대표청구항

What is claimed is: 1. A formulation consisting essentially of: Vitamin A (palmitate) 5,000 I.U. Beta-carotene (from natural D. salina) 15 mg Vitamin D-3 (cholecalciferol) 400 I.U. Natural soucre Vitamin E (d-alpha tocopherol) 100 I.U. (d-alpha tocopheryl acid succinat

이 특허에 인용된 특허 (53)

  1. Togasaki Keiichi,JPX, Active oxygen free radical scavenging agent.
  2. Gubernick Joseph ; Marenus Kenneth D. ; Pelle Edward ; Declercq Lieve,BEX ; Maes Daniel H., Antioxidant mixture.
  3. Gubernick Joseph ; Marenus Kenneth D. ; Pelle Edward ; Declercq Lieve,BEX ; Maes Daniel H., Antioxidant mixture comprising tocopherol.
  4. Hersh Theodore, Antioxidant preparation.
  5. Jurgen F. Pascoe DE, Ascorbic acid as an adjuvant in the treatment of malignant tumors using chemotherapy and radiotherapy.
  6. Paul Stephen M. (Rancha Santa Margarita CA), Ascorbic acid compositions providing enhanced human immune system activity.
  7. Graus, Yvo Maria Franciscus; Smit, Hobbe Friso; Osterhaus, Albertus Dominicus Marcellinus Erasmus; Hageman, Robert Johan Joseph, Chlorogenic acid and an analog thereof for immune system stimulation.
  8. Rosenbloom, Richard Allen, Composition and method for prevention, reduction and treatment of radiation dermatitis.
  9. Marjorie F. Lou ; Nalini Raghavachari ; Fengyu Qiao, Composition and method for the prevention and treatment of oxidative damage in ocular tissues.
  10. Sole Michael J.,CAXITX M6B 1L3 ; Jeejeebhoy Khursheed N.,CAXITX M4V 2V5, Composition for improvement of cellular nutrition and mitochondrial energetics.
  11. Cavazza, Claudio, Composition for the prevention of muscle fatique and skeletal muscle adaptation of strenuous exercise.
  12. Giordano, John A.; Balzer, Charles, Compositions and methods for nutrition supplementation.
  13. Giordano, John A.; Balzer, Charles, Compositions and methods for prophylactic and therapeutic supplementation of nutrition in subjects.
  14. Giordano, John A.; Balzer, Charles, Compositions and methods for prophylactic and therapeutic supplementation of nutrition in subjects.
  15. Cochran Timothy M., Compositions used in human treatment.
  16. Fleischner Albert M., Dietary supplements for each specific blood type.
  17. Maxwell Andrew J. ; Cooke John P., Enhancement of exercise performance by augmenting endogenous nitric oxide production or activity.
  18. Grossman Shlomo (Ramat Gan ILX) Albeck Michael (Ramat Gan ILX), Food supplements.
  19. Guy Miller ; Lesley A. Brown, Formulations of tocopherols and methods of making and using them.
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  22. Thomas Peter G. ; Wade A. Michael, Histidine containing nutriceutical.
  23. Paul Stephen M. (San Clemente CA) Ashmead H. DeWayne (Fruit Heights UT), Improved sustained energy and anabolic composition and method of making.
  24. Ben-Amotz Ami,ILX ; Weshler Zeev,ILX ; Yatziv Shaul,ILX ; Sela Mordechai,ILX, Irradiation protection method.
  25. Bland Jeffrey S. (957 11th La. Fox Island WA 98333), Medical food composition for metabolic detoxification.
  26. Passwater Richard A. ; Olson David M., Method and composition to reduce cancer incidence.
  27. Petrus, Edward J., Method and compositions for treatment of the aging eye.
  28. Rosenberg, Thomas D.; Deffner, Kathleen, Method for supplementing the diet.
  29. Wagle, Dilip; Gall, Martin; Bell, Stanley C.; LaVoie, Edmond J., Method for treating fibrotic diseases or other indications utilizing thiazole, oxazole and imidazole compounds.
  30. Shibnath Ghosal IN, Method of blocking free radical processes which result in mediated pathology without deleterious pro-oxidant side reactions.
  31. Fleming Thomas E. ; Mansmann ; Jr. Herbert C., Methods and compositions for the prevention and treatment of immunological disorders, inflammatory diseases and infectio.
  32. Hirsch Gerald P. (Atlanta GA) Bayless Robert K. (Austin TX), Methods for inhibiting inflammatory ischemic, thrombotic and cholesterolemic disease response with methionine compounds.
  33. Howard K. Shapiro, Methods of treating chronic inflammatory diseases using carbonyl trapping agents.
  34. Riley Patricia A., Modular system of dietary supplement compositions for optimizing health benefits and methods.
  35. Prasad, Kedar N.; Haase, Gerald M., Multiple antioxidant micronutrients.
  36. Ghosal Shibnath,INX, Natural antioxidant compositions, method for obtaining same and cosmetic, pharmaceutical and nutritional formulations thereof.
  37. Mirsky Nitsa,ILX ; Schachter Alona,ILX ; Sussan Sherbel,ILX, Natural extracted and synthetic antioxidant compositions.
  38. Bragaglia Anthony Joseph, Nutraceutical composition for protection against solar radiation.
  39. Andon Mark B. (Fairfield OH) Leis ; Jr. Paul D. (Hamilton OH), Nutrient supplement compositions providing physiologic feedback.
  40. DeMichele Stephen J. (Dublin OH) Gregory Timothy J. (Gahanna OH), Nutritional product for pulmonary patients.
  41. Markowitz John S., Nutritional supplement.
  42. Bland Jeffrey, Optimal nutritional supplement for men.
  43. Højgaard, Bent; Poulsen, Henrik Enghusen; Salonen, Jukka, Pharmaceutical delivery system for vitamin C and vitamin E and use of a combination of vitamin C and E for preventing or treating conditions involving oxidative stress.
  44. DeMichele Stephen J. ; McEwen John W. ; Wood Steven M., Product and method reduce stress induced immune suppression.
  45. DeMichele Stephen J. ; Wood Steven M., Product and method to reduce stress induced immune suppression.
  46. Stephen J. DeMichele ; John W. McEwen ; Steven M. Wood, Product and method to reduce stress induced immune suppression.
  47. Kamarei A. Reza, Refrigeration-shelf-stable ready-to-drink complete nutritional compositions and products.
  48. Kesselman Morris (Belmar NJ) Purkaystha Abdur R. (Bronx NY) Cahill James (Riverdale NY), Stabilization of multivitamin/trace elements formulations.
  49. Murad Howard, Stable pharmaceutical compositions including ascorbic acid and methods of using same.
  50. Byrne, Theresa A.; Somerville, Joanne A., Therapeutic glutamine and N-actyl-cysteine composition.
  51. Thomas J. Slaga ; Daryl L. DeLuca ; William S. Sparks, Time release formulation of vitamins, minerals and other beneficial supplements.
  52. Forceville, Xavier; Vitoux, Dominique, Use of selenium for treating patients suffering from systemic inflammatory response syndrome (SIRS), and composition for implementing said treatment.
  53. Motschan Georges (Schnbeinstrasse 21 4056 Basel CHX), Utilization of a single vitamin or a combination of various vitamins.

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  2. Dohil, Ranjan; Schneider, Jerry, Enterically coated cysteamine, cystamine and derivatives thereof.
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  4. Dohil, Ranjan; Schneider, Jerry, Enterically coated cysteamine, cystamine and derivatives thereof.
  5. Dohil, Ranjan; Schneider, Jerry, Enterically coated cysteamine, cystamine and derivatives thereof.
  6. Dohil, Ranjan; Schneider, Jerry, Enterically coated cysteamine, cystamine and derivatives thereof.
  7. Dohil, Ranjan; Schneider, Jerry, Enterically coated cysteamine, cystamine and derivatives thereof.
  8. Dohil, Ranjan; Schneider, Jerry, Enterically coated cysteamine, cystamine and derivatives thereof.
  9. Dohil, Ranjan; Schneider, Jerry, Enterically coated cysteamine, cystamine and derivatives thereof.
  10. Dohil, Ranjan; Schneider, Jerry, Enterically coated cysteamine, cystamine and derivatives thereof.
  11. Dohil, Ranjan; Schneider, Jerry, Enterically coated cysteamine, cystamine and derivatives thereof.
  12. Demopoulos, Harry B.; Davis, Kevin, Glutathione formulation and method of use.
  13. DesJardin, Michael; Johnson, Mark, Methods for storing cysteamine formulations and related methods of treatment.
  14. Dohil, Ranjan; Schneider, Jerry, Methods of treating non-alcoholic steatohepatitis (NASH) using cysteamine products.
  15. Dohil, Ranjan; Schneider, Jerry, Methods of treating non-alcoholic steatohepatitis (NASH) using cysteamine products.
  16. Dohil, Ranjan; Schneider, Jerry, Methods of treating non-alcoholic steatohepatitis (NASH) using cysteamine products.
  17. Dohil, Ranjan; Schneider, Jerry, Methods of treating non-alcoholic steatohepatitis (NASH) using cysteamine products.
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