Algorithm sensor augmented bolus estimator for semi-closed loop infusion system
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/00
A61B-005/05
A61M-001/00
A61M-031/00
출원번호
UP-0322489
(2005-12-30)
등록번호
US-7547281
(2009-07-01)
발명자
/ 주소
Hayes, Andrew C.
Mastrototaro, John J.
Moberg, Sheldon B.
Mueller, Jr., John C.
Clark, H. Bud
Tolle, Mike Charles Vallet
Williams, Gary L.
Wu, Bihong
Steil, Garry M.
출원인 / 주소
Medtronic MiniMed, Inc.
인용정보
피인용 횟수 :
313인용 특허 :
35
초록▼
An infusion system is for infusing a fluid into the body of a patient. The infusion system includes at least one sensor for monitoring blood glucose concentration of the patient and an infusion device for delivering fluid to the patient. The sensor produces at least one sensor signal input. The infu
An infusion system is for infusing a fluid into the body of a patient. The infusion system includes at least one sensor for monitoring blood glucose concentration of the patient and an infusion device for delivering fluid to the patient. The sensor produces at least one sensor signal input. The infusion device uses the at least one sensor signal input and a derivative predicted algorithm to determine future blood glucose levels. The infusion device delivers fluid to the patient when future blood glucose levels are in a patient's target range. The infusion device is capable of suspending and resuming fluid delivery based on future blood glucose levels and a patient's low shutoff threshold. The infusion device suspends fluid delivery when future blood glucose levels falls below the low shutoff threshold. The infusion device resumes fluid delivery when a future blood glucose level is above the low shutoff threshold.
대표청구항▼
What is claimed is: 1. An infusion system for infusing a fluid into the body of a patient, the infusion system comprising: at least one sensor for monitoring blood glucose concentration of the patient, wherein the sensor produces at least one sensor signal input; and an infusion device for deliveri
What is claimed is: 1. An infusion system for infusing a fluid into the body of a patient, the infusion system comprising: at least one sensor for monitoring blood glucose concentration of the patient, wherein the sensor produces at least one sensor signal input; and an infusion device for delivering fluid to the patient, wherein the infusion device uses the at least one sensor signal input and a derivative predicted algorithm to determine future blood glucose levels, the derivative predicted algorithm calculates a first derivative of a sensor current sample from the at least one sensor signal input at time period n, and then calculates a first derivative of a sensor glucose value from the at least one sensor signal input using the first derivative of the sensor current sample to determine future blood glucose levels, the infusion device is capable of automatically suspending and resuming fluid delivery based on future blood glucose levels and the patient's predefined low shutoff threshold, and the infusion device recommends more fluid delivery based on a positive derivative from the derivative predicted algorithm, and the infusion device recommends less fluid delivery based on a negative derivative from the derivative predicted algorithm. 2. The system according to claim 1, wherein the infusion device delivers fluid to the patient when future blood glucose levels are in the patient's predefined target range. 3. The system according to claim 1, wherein the infusion device automatically suspends fluid delivery when a future blood glucose level falls below the predefined low shutoff threshold. 4. The system according to claim 1, wherein the infusion device automatically resumes fluid delivery when a future blood glucose level is above the predefined low shutoff threshold. 5. The system according to claim 1, wherein the predefined low shutoff threshold is always above the infusion system's lowest shutoff threshold. 6. The system according to claim 1, wherein the infused fluid is insulin. 7. The system according to claim 1, wherein the infusion system further includes an alarm to provide alerts to the patient. 8. The system according to claim 7, wherein the patient selects at least one alarm to activate, wherein the at least one alarm includes an audible alarm for providing audible alerts, a vibration alarm for providing tactile alert, and a visual alarm for providing visual alerts. 9. The system according to claim 1, wherein the derivative predicted algorithm utilizes at least one of current blood glucose concentrations, meal carbohydrate content, sensor current sample at time period n, system calibration factor, and insulin-on-board at time period n. 10. The system according to claim 1, wherein the first derivative of the sensor current sample is calculated from a slope of the sensor current sample versus time using a Savitzky-Golay finite impulse response filter. 11. An infusion system for infusing a fluid into the body of a patient, the infusion system comprising: at least one sensor for monitoring blood glucose concentration of the patient, wherein the sensor produces at least one sensor signal input; and an infusion device for delivering fluid to the patient, wherein the infusion device uses the at least one sensor signal input and a derivative predicted algorithm to determine future blood glucose levels, the derivative predicted algorithm calculates a first derivative of a sensor current sample from the at least one sensor signal input at time period n, and then calculates a first derivative of a sensor glucose value from the at least one sensor signal input using the first derivative of the sensor current sample to determine future blood glucose levels, the infusion device is capable of automatically suspending and resuming fluid delivery based on future blood glucose levels and the patient's predefined low shutoff threshold, and the infusion device recommends a particular type of bolus for delivery based on the derivative predicted algorithm. 12. The system according to claim 11, wherein the particular type of bolus is selected from the group consisting of a dual wave bolus and a square wave bolus. 13. The system according to claim 11, wherein the infusion device delivers fluid to the patient when future blood glucose levels are in the patient's predefined target range. 14. The system according to claim 11, wherein the infusion device automatically suspends fluid delivery when a future blood glucose level falls below the predefined low shutoff threshold. 15. The system according to claim 11, wherein the infusion device automatically resumes fluid delivery when a future blood glucose level is above the predefined low shutoff threshold. 16. The system according to claim 11, wherein the predefined low shutoff threshold is always above the infusion system's lowest shutoff threshold. 17. The system according to claim 11, wherein the infused fluid is insulin. 18. The system according to claim 11, wherein the infusion system further includes an alarm to provide alerts to the patient. 19. The system according to claim 18, wherein the patient selects at least one alarm to activate, wherein the at least one alarm includes an audible alarm for providing audible alerts, a vibration alarm for providing tactile alert, and a visual alarm for providing visual alerts. 20. The system according to claim 11, wherein the derivative predicted algorithm utilizes at least one of current blood glucose concentrations, meal carbohydrate content, sensor current sample at time period n, system calibration factor, and insulin-on-board at time period n. 21. The system according to claim 11, wherein the first derivative of the sensor current sample is calculated from a slope of the sensor current sample versus time using a Savitzky-Golay finite impulse response filter.
Say James ; Tomasco Michael F. ; Heller Adam ; Gal Yoram,ILX ; Aria Behrad ; Heller Ephraim ; Plante Phillip John ; Vreeke Mark S. ; Friedman Keith A. ; Colman Fredric C., Analyte monitoring device and methods of use.
Bcker Dirk (Heidelberg DEX) Haar Hans-Peter (Wiesloch DEX) Blasberg Peter (Weinheim DEX) Kotulla Reinhard (Lambsheim DEX), Analytical system for monitoring a substance to be analyzed in patient-blood.
Enzer Steven (Brooklyn MI) Burgess Bruce M. (Ann Arbor MI) Wyman Jack S. (Ann Arbor MI) Hendershot Ricky (Ann Arbor MI), Apparatus for chemical measurement of blood characteristics.
Kraegen Edward W. (Bondi Junction AUX) Lazarus Leslie (St. Ives AUX) Bell David J. (Strathfield AUX) Chisholm Donald J. (Roseville AUX), Apparatus for improving blood sugar control in diabetics.
Steil, Garry M.; Rebrin, Kerstin; Goode, Jr., Paul V.; Mastrototaro, John J.; Purvis, Richard E.; Van Antwerp, William P.; Shin, John J.; Talbot, Cary D., Closed loop system for controlling insulin infusion.
Bowman Robert J. (Salt Lake City UT) Westenskow Dwayne R. (Salt Lake City UT), Closed-loop infusion system, both method and apparatus, based on real time urine measurement.
Conn, Thomas E.; Ford, Russell; Potts, Russell O.; Soni, Pravin L.; Tamada, Janet A.; Tierney, Michael J., Devices and methods for frequent measurement of an analyte present in a biological system.
Schulman Joseph H. (Santa Clarita CA) Rule ; III Orville R. (Los Angeles CA) Whitmoyer David I. (Los Angeles CA) Lebel Ronald J. (Sherman Oaks CA) Lucisano Joseph Y. (Saugus CA) Mann Alfred E. (Bever, Glucose monitoring system.
Desai,Shashi P.; Dunn,Timothy C.; Lesho,Matthew J.; Potts,Russell O.; Tamada,Janet A.; Wei,Charles W., Methods for computing rolling analyte measurement values, microprocessors comprising programming to control performance of the methods, and analyte monitoring devices employing the methods.
Clement D. Bouchard ; Robert J. Bryant ; Lawrence B. Gray ; Geoff P. Spencer, Pumping cartridge including a bypass valve and method for directing flow in a pumping cartridge.
DeBelser, David; Hetchler, Clinton Robert; Sours, David Pardee; Kersch, Michael Wade, Advanced step therapy delivery for an ambulatory infusion pump and system.
Hayes, Andrew C.; Mastrototaro, John J.; Moberg, Sheldon B.; Mueller, Jr., John C.; Clark, H. Bud; Tolle, Mike Charles Vallet; Williams, Gary L.; Wu, Bihong; Steil, Garry M., Algorithm sensor augmented bolus estimator for semi-closed loop infusion system.
Hayes, Andrew C.; Mastrototaro, John J.; Moberg, Sheldon B.; Mueller, Jr., John C.; Clark, H. Bud; Tolle, Mike Charles Vallet; Williams, Gary L.; Wu, Bihong; Steil, Garry M., Algorithm sensor augmented bolus estimator for semi-closed loop infusion system.
Nekoomaram, Saeed; Fennell, Martin J.; Sloan, Mark Kent; He, Lei; Sicurello, Jeffery Mario, Analyte monitoring system and methods for managing power and noise.
Cabiri, Oz; Filman, Reuven Y.; Bar-El, Yossi, Apparatuses for securing components of a drug delivery system during transport and methods of using same.
Karan, Jai; Tan, Annie; Taub, Marc B.; Dunn, Timothy C.; Goldsmith, Joel; Neuhaus, Christine M.; Rossi, Stephen A., Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same.
Harper, Wesley Scott; Tan, Annie C.; Dunn, Timothy Christian; Sloan, Mark Kent; Doniger, Kenneth J.; McGarraugh, Geoffrey V.; Love, Michael; Yee, Phillip; Hayter, Gary Alan; Taub, Marc Barry; Peyser, Thomas A.; Pani, Michael A.; Jennewine, R. Curtis; Berman, Glenn Howard, Displays for a medical device.
Braig, James R.; Keenan, Richard; Rule, Peter; Rivas, Gil; Seetharaman, Mahesh, Fluid component analysis system and method for glucose monitoring and control.
Braig, James R.; Keenan, Richard; Rule, Peter; Rivas, Gil; Seetharaman, Mahesh, Fluid component analysis systems and methods for glucose monitoring and control.
Braig, James R.; Keenan, Richard; Rule, Peter; Rivas, Gil; Seetharaman, Mahesh, Fluid component analysis systems and methods for glucose monitoring and control.
Nelson, Charles L.; Sloan, Mark K.; Jin, Robert Y.; Jiang, Feng; Chen, Jen-Chyun; Anderson, III, Arthur Eugene; Liamos, Charles T.; Limbach, Douglas C., Glucose measuring device for use in personal area network.
Nelson, Charles L.; Sloan, Mark K.; Jin, Robert Y.; Jiang, Feng; Chen, Jen-Chyun; Anderson, III, Arthur Eugene; Liamos, Charles T.; Limbach, Douglas C., Glucose measuring device for use in personal area network.
Nelson, Charles L.; Sloan, Mark K.; Jin, Robert Y.; Jiang, Feng; Chen, Jen-Chyun; Anderson, III, Arthur Eugene; Liamos, Charles T.; Limbach, Douglas C., Glucose measuring device for use in personal area network.
Nelson, Charles L.; Sloan, Mark Kent; Jin, Robert Y.; Jiang, Feng; Chen, Jen-Chyun; Anderson, III, Arthur Eugene; Liamos, Charles T., Glucose measuring device for use in personal area network.
DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
Verhoef, Erik T.; DiPerna, Paul M.; Rosinko, Mike; Williamson, Mark; Kruse, Geoffrey A.; Ulrich, Thomas R.; Lamb, Phil; Saint, Sean; Michaud, Michael; Trevaskis, William, Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
Bernstein, Daniel Milfred; Fennell, Martin J.; Sloan, Mark Kent; He, Lei; Hayter, Gary Alan; Kiaie, Namvar; Cole, Jean-Pierre; Taub, Marc Barry, Medical devices and methods.
Budiman, Erwin Satrya, Method and apparatus for improving lag correction during in vivo measurement of analyte concentration with analyte concentration variability and range data.
Hayter, Gary Alan; McGarraugh, Geoffrey V.; Naegeli, Andrew H.; Mazza, John Charles; Feldman, Benjamin Jay; Harper, Wesley Scott, Method and apparatus for providing analyte sensor calibration.
Hayter, Gary; McGarraugh, Geoffrey V.; Naegeli, Andrew H.; Mazza, John C.; Feldman, Benjamin J.; Harper, Scott, Method and apparatus for providing analyte sensor calibration.
Hayter, Gary Alan; McGarraugh, Geoffrey V.; Doniger, Kenneth J., Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary Alan; McGarraugh, Geoffrey V.; Doniger, Kenneth J., Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary Alan; McGarraugh, Geoffrey V.; Naegeli, Andrew H.; Mazza, John Charles; Feldman, Benjamin Jay, Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary Alan; McGarraugh, Geoffrey V.; Naegeli, Andrew H.; Mazza, John Charles; Feldman, Benjamin Jay, Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary Alan; McGarraugh, Geoffrey V.; Naegeli, Andrew H.; Mazza, John Charles; Feldman, Benjamin Jay, Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary; He, Lei; Sloan, Mark K.; Feldman, Benjamin J., Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary; McGarraugh, Geoffrey V.; Doniger, Kenneth J., Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary; McGarraugh, Geoffrey V.; Doniger, Kenneth J., Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary; McGarraugh, Geoffrey V.; Naegeli, Andrew H.; Mazza, John C.; Feldman, Benjamin J., Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary; McGarraugh, Geoffrey V.; Naegeli, Andrew H.; Mazza, John C.; Feldman, Benjamin J., Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary; McGarraugh, Geoffrey V.; Naegeli, Andrew H.; Mazza, John C.; Feldman, Benjamin J., Method and apparatus for providing data processing and control in a medical communication system.
Hayter, Gary; McGarraugh, Geoffrey V.; Naegeli, Andrew H.; Mazza, John C.; Feldman, Benjamin J., Method and apparatus for providing data processing and control in a medical communication system.
Doniger, Kenneth J.; Berman, Glenn Howard; McGarraugh, Geoffrey V., Method and apparatus for providing notification function in analyte monitoring systems.
Doniger, Kenneth J.; Berman, Glenn Howard; McGarraugh, Geoffrey V., Method and apparatus for providing notification function in analyte monitoring systems.
Doniger, Kenneth J.; Budiman, Erwin Satrya; Hayter, Gary Alan, Method and device for early signal attenuation detection using blood glucose measurements.
Doniger, Kenneth J.; Budiman, Erwin Satrya; Hayter, Gary Alan, Method and device for early signal attenuation detection using blood glucose measurements.
Hayter, Gary Alan; Budiman, Erwin Satrya; Doniger, Kenneth J.; Mazza, John Charles, Method and system for dynamically updating calibration parameters for an analyte sensor.
Hayter, Gary Alan; Budiman, Erwin Satrya; Doniger, Kenneth J.; Mazza, John Charles, Method and system for dynamically updating calibration parameters for an analyte sensor.
Hayter, Gary Alan; Budiman, Erwin Satrya; Doniger, Kenneth J.; Mazza, John Charles, Method and system for dynamically updating calibration parameters for an analyte sensor.
Hayter, Gary; Budiman, Erwin S.; Doniger, Kenneth J.; Mazza, John C., Method and system for dynamically updating calibration parameters for an analyte sensor.
Hayter, Gary Alan; Doniger, Kenneth J.; Budiman, Erwin Satrya; Zhang, Songbiao; Mazza, John Charles, Method and system for providing calibration of an analyte sensor in an analyte monitoring system.
Hayter, Gary Alan; Doniger, Kenneth J.; Budiman, Erwin Satrya; Zhang, Songbiao; Mazza, John Charles, Method and system for providing calibration of an analyte sensor in an analyte monitoring system.
Hayter, Gary; Doniger, Kenneth J.; Budiman, Erwin S.; Zhang, Songbiao; Mazza, John C., Method and system for providing calibration of an analyte sensor in an analyte monitoring system.
Sicurello, Jeffery Mario; Dinh, Hung; Sloan, Mark Kent, Method and system for providing data communication in continuous glucose monitoring and management system.
Sicurello, Jeffery Mario; Dinh, Hung; Sloan, Mark Kent, Method and system for providing data communication in continuous glucose monitoring and management system.
Sicurello, Jeffery Mario; Dinh, Hung; Sloan, Mark Kent, Method and system for providing data communication in continuous glucose monitoring and management system.
Sicurello, Jeffery Mario; Dinh, Hung; Sloan, Mark Kent, Method and system for providing data communication in continuous glucose monitoring and management system.
Sicurello, Jeffrey Mario; Dinh, Hung; Sloan, Mark Kent, Method and system for providing data communication in continuous glucose monitoring and management system.
Breton, Marc D.; Kovatchev, Boris P.; Budiman, Erwin S.; Doniger, Kenneth J., Method, system and computer program product for real-time detection of sensitivity decline in analyte sensors.
Breton, Marc D.; Kovatchev, Boris P.; Budiman, Erwin S.; Doniger, Kenneth J., Method, system and computer program product for real-time detection of sensitivity decline in analyte sensors.
Breton, Marc D.; Kovatchev, Boris P.; Budiman, Erwin Satrya; Doniger, Kenneth J., Method, system and computer program product for real-time detection of sensitivity decline in analyte sensors.
Cole, Jean-Pierre, Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems.
Palerm, Cesar C.; Lintereur, Louis J.; Monirabbasi, Salman; Holtzclaw, Kris R.; Desborough, Lane, Predictive infusion device operations and related methods and systems.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.