초록 ▼

A method for surface modification of a material by means of introducing the phosphorylcholine group represented by the following formula (1-1) onto the surface of the material by treating a material having amino groups with a chemical compound containing an aldehyde derivative obtained by the oxidat

A method for surface modification of a material by means of introducing the phosphorylcholine group represented by the following formula (1-1) onto the surface of the material by treating a material having amino groups with a chemical compound containing an aldehyde derivative obtained by the oxidative ring-opening reaction of glycerophosphorylcholine. The method of the present invention provides various materials such as medical materials having superior biocompatibility and hydrophilicity.

대표청구항 ▼

The invention claimed is: 1. A chromatography packing comprising: a silica gel carrier comprised of porous spherical particles having an average particle size of 1-200 micrometers and an average pore size of 1-2000 angstroms, said carrier having a carrier surface having phosphorylcholine groups, re

The invention claimed is: 1. A chromatography packing comprising: a silica gel carrier comprised of porous spherical particles having an average particle size of 1-200 micrometers and an average pore size of 1-2000 angstroms, said carrier having a carrier surface having phosphorylcholine groups, represented by the following formula (3-1): wherein amino groups are directly introduced to the carrier surface, and then an aldehyde derivative obtained by the oxidative ring-opening reaction of glycerophosphorylcholine is reacted with said amino groups, so as to directly chemically bond the phosphorylcholine groups to the carrier surface.