[미국특허]
Blood purifying device and method of operating the same
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B01D-061/32
B01D-061/24
B01D-061/26
B01D-061/28
출원번호
UP-0523968
(2003-08-04)
등록번호
US-7618542
(2009-11-27)
우선권정보
JP-2002-231007(2002-08-08)
국제출원번호
PCT/JP03/009878
(2003-08-04)
§371/§102 date
20051202
(20051202)
국제공개번호
WO04/014463
(2004-02-19)
발명자
/ 주소
Okazaki, Soichirou
출원인 / 주소
Asahi Kasei Medical Co., Ltd.
대리인 / 주소
Young & Thompson
인용정보
피인용 횟수 :
1인용 특허 :
1
초록▼
A blood purifying apparatus particularly suitable for continuous blood purification, and a method of controlling the same whereby the weight of body fluid removed from a patient and a feed weight to the patient can be more accurately controlled. A blood purifying apparatus 50 adapted for the continu
A blood purifying apparatus particularly suitable for continuous blood purification, and a method of controlling the same whereby the weight of body fluid removed from a patient and a feed weight to the patient can be more accurately controlled. A blood purifying apparatus 50 adapted for the continuous blood purification includes a drain C, a dialysate feed A, and a replacement fluid feed B, which are equipped with transfer pumps 5, 6, 7, respectively, reservoir containers 8, 9, and 10, respectively, that are capable of storing a predetermined volume, and fluid level sensors 11, 12, and 13, respectively. The blood purifying apparatus further includes a single weightmeter 20 capable of measuring the reservoir containers 8, 9, and 10 all at the same time.
대표청구항▼
The invention claimed is: 1. A blood purifying apparatus comprising a dialysate feed means, a replacement fluid feed means, a drain means, a blood purifying device, and a blood circulation path consisting of a blood drawing line and a blood retransfusing line, wherein: said dialysate feed means com
The invention claimed is: 1. A blood purifying apparatus comprising a dialysate feed means, a replacement fluid feed means, a drain means, a blood purifying device, and a blood circulation path consisting of a blood drawing line and a blood retransfusing line, wherein: said dialysate feed means comprises: a dialysate transfer line of which one end is connected to said blood purifying device and the other end connected to a dialysate reservoir unit; a dialysate transfer pump disposed in said dialysate transfer line; a dialysate reservoir container connected to a dialysate branch line branching off on an inlet side of said dialysate transfer pump; and a first shutoff valve attached to said dialysate transfer line upstream of a branch portion; said replacement fluid feed means comprises: a replacement fluid feeding line of which one end is connected to said blood retransfusing line and the other end connected to a replacement fluid reservoir unit; a replacement fluid transfer pump disposed in said replacement fluid feeding line; a replacement fluid reservoir container connected to a replacement fluid branch line branching off on an inlet side of said replacement fluid transfer pump; and a second shutoff valve attached to said replacement fluid transfer line upstream of a branch portion; said drain means comprises: a drain line of which one end is connected to said blood purifying device and the other end opened; a drain transfer pump disposed in said drain line; a drain reservoir container connected to a drain branch line branching off on an outlet side of said drain transfer pump; and a third shutoff valve attached to said drain line downstream of a branch portion, wherein the dialysate reservoir container, the replacement fluid reservoir container and the drain reservoir container are each equipped with a fluid level sensor, said apparatus further comprising a weightmeter for weighing the dialysate reservoir container, the replacement fluid reservoir container and the drain reservoir container at once, and a control unit for controlling the opening and closing of said first, second and third shutoff valves and the pump flow rate of each of said dialysate transfer pump, said replacement fluid transfer pump and said drain transfer pump, wherein said control unit performs a removed body fluid weight measuring phase consisting of: a first phase in which the first, second and third shutoff valves are opened, whereby said dialysate reservoir container and said replacement fluid reservoir container are each filled with a fluid while at the same time a fluid is discharged from said drain reservoir container; and a second phase in which said apparatus is controlled with each of said first, second and third shutoff valves closed, and a change in the total fluid weight in said dialysate reservoir container, said replacement fluid reservoir container, and said drain reservoir container during the operation of said apparatus is acquired from information provided by said weightmeter in order to weigh the removal weight of body fluid, wherein said control unit controls the flow rate of at least one of said dialysate transfer pump, said replacement fluid transfer pump and said drain transfer pump such that a desired water-removed weight can be obtained in said second phase. 2. The blood purifying apparatus according to claim 1, wherein said control unit performs a feed weight measuring phase consisting of: a third phase in which each of said first, second and third shutoff valves is opened, whereby said dialysate reservoir container and said replacement fluid reservoir container are filled with individual fluids while at the same time a fluid is discharged from said drain reservoir container; and a fourth phase in which said apparatus is controlled with only the first shutoff valve and the second shutoff valve closed, and in which a change in the total fluid weight in said dialysate reservoir container, said replacement fluid reservoir container, and said drain reservoir container is acquired from information provided by said weightmeter so as to calculate a feed weight which is the sum of the weight of replacement fluid and the weight of the dialysate, wherein said control unit controls the flow rate of the dialysate transfer pump and the replacement fluid transfer pump such that a desired feed weight can be obtained during the fourth phase. 3. The blood purifying apparatus according to claim 2, wherein said control unit controls the flow rate of at least one of the dialysate transfer pump, the replacement fluid transfer pump and the drain transfer pump based on an arbitrary combination of said removed body fluid weight measuring phase and said feed weight measuring phase. 4. The blood purifying apparatus according to claim 2, wherein said control unit controls the flow rate of at least one of the dialysate transfer pump, the replacement fluid transfer pump and the drain transfer pump by alternately repeating said removed body fluid weight measuring phase and said feed weight measuring phase. 5. A method of controlling a blood purifying apparatus, said apparatus comprising a dialysate feed means, a replacement fluid feed means, a drain means, a blood purifying device, and a blood circulation path consisting of a blood drawing line and a blood retransfusing line, wherein: said dialysate feed means comprises: a dialysate transfer line of which one end is connected to said blood purifying device and the other end connected to a dialysate reservoir unit; a dialysate transfer pump disposed in said dialysate transfer line; a dialysate reservoir container connected to a dialysate branch line branching off on an inlet side of said dialysate transfer pump; and a first shutoff valve attached to said dialysate transfer line upstream of a branch portion; said replacement fluid feed means comprises: a replacement fluid feeding line of which one end is connected to said blood retransfusing line and the other end connected to a replacement fluid reservoir unit; a replacement fluid transfer pump disposed in said replacement fluid feed line; a replacement fluid reservoir container connected to a replacement fluid branch line branching off on an inlet side of said replacement fluid transfer pump; and a second shutoff valve attached to said replacement fluid transfer line upstream of a branch portion; said drain means comprises: a drain line of which one end is connected to said blood purifying device and the other end opened; a drain transfer pump disposed in said drain line; a drain reservoir container connected to a drain branch line branching off on an outlet side of said drain transfer pump; and a third shutoff valve attached to said drain line downstream of a branch portion, wherein the dialysate reservoir container, the replacement fluid reservoir container and the drain reservoir container are each equipped with a fluid level sensor, said apparatus further comprising a weightmeter for weighing the dialysate reservoir container, the replacement fluid reservoir container and the drain reservoir container at once, and a control unit for controlling the opening and closing of said first, second and third shutoff valves and the pump flow rate of each of said dialysate transfer pump, said replacement fluid transfer pump and said drain transfer pump, said method comprising performing a removed body fluid weight measuring phase consisting of: a first phase of opening the first, second and third shutoff valves, whereby said dialysate reservoir container and said replacement fluid reservoir container are each filled with a fluid while at the same time a fluid is discharged from said drain reservoir container; and a second phase of closing each of said first, second and third shutoff valves, and acquiring a change in the total fluid weight in said dialysate reservoir container, said replacement fluid reservoir container, and said drain reservoir container during the operation of said apparatus from information provided by said weightmeter in order to weigh the removal weight of body fluid, wherein said control unit controls the flow rate of at least one of said dialysate transfer pump, said replacement fluid transfer pump and said drain transfer pump such that a desired removal weight of body fluid can be obtained in said second phase. 6. A method of controlling a blood purifying apparatus, said apparatus comprising a dialysate feed means, a replacement fluid feed means, a drain means, a blood purifying device, and a blood circulation path consisting of a blood drawing line and a blood retransfusing line, wherein: said dialysate feed means comprises: a dialysate transfer line of which one end is connected to said blood purifying device and the other end connected to a dialysate reservoir unit; a dialysate transfer pump disposed in said dialysate transfer line; a dialysate reservoir container connected to a dialysate branch line branching off on an inlet side of said dialysate transfer pump; and a first shutoff valve attached to said dialysate transfer line upstream of a branch portion; said replacement fluid feed means comprises: a replacement fluid feeding line of which one end is connected to said blood retransfusing line and the other end connected to a replacement fluid reservoir unit; a replacement fluid transfer pump disposed in said replacement fluid feeding line; a replacement fluid reservoir container connected to a replacement fluid branch line branching off on an inlet side of said replacement fluid transfer pump; and a second shutoff valve attached to said replacement fluid transfer line upstream of a branch portion; said drain means comprises: a drain line of which one end is connected to said blood purifying device and the other end opened; a drain transfer pump disposed in said drain line; a drain reservoir container connected to a drain branch line branching off on an outlet side of said drain transfer pump; and a third shutoff valve attached to said drain line downstream of a branch portion, wherein the dialysate reservoir container, the replacement reservoir container and the drain reservoir container are each equipped with a fluid level sensor, said apparatus further comprising a weightmeter for weighing the dialysate reservoir container, the replacement fluid reservoir container and the drain reservoir container at once, and a control unit for controlling the opening and closing of said first, second and third shutoff valves and the pump flow rate of each of said dialysate transfer pump, said replacement fluid transfer pump and said drain transfer pump, said method comprising performing a feed weight measuring phase consisting of: a first phase of opening each of said first, second and third shutoff valves whereby said dialysate reservoir container and said replacement fluid reservoir container are filled with individual fluids while at the same time discharging a fluid from said drain reservoir container; and a second phase of controlling said apparatus by closing only the first shutoff valve and the second shutoff valve, and acquiring a change in the total fluid weight in said dialysate reservoir container, said replacement fluid reservoir container, and said drain reservoir container from information provided by said weightmeter so as to calculate a feed weight which is the sum of the weight of replacement fluid and the weight of the dialysate, wherein said control unit controls the flow rate of at least one of said dialysate transfer pump, said replacement fluid transfer pump and said drain transfer pump such that a desired feed weight can be obtained during the second phase. 7. The method of controlling the blood purifying apparatus according to claim 5, said control method further comprising: arbitrarily combining the control method based on performing the removed body fluid weight measuring phase and based on performing a feed weight measuring phase, said feed weight measuring phase consisting of: a third phase of opening each of said first, second and third shutoff valves whereby said dialysate reservoir container and said replacement fluid reservoir container are filled with individual fluids while at the same time discharging a fluid from said drain reservoir container; and a fourth phase of controlling said apparatus by closing only the first shutoff valve and the second shutoff valve, and acquiring a change in total fluid weight in said dialysate reservoir container, said replacement fluid reservoir container, and said drain reservoir container from information provided by said weightmeter so as to calculate a feed weight which is the sum of the weight of replacement fluid and the weight of the dialysate, wherein said control unit controls the flow rate of at least one of said dialysate transfer pump, said replacement fluid transfer pump and said drain transfer pump such that a desired feed weight can be obtained during the fourth phase. 8. The method of controlling the blood purifying apparatus according to claim 5, said control method further comprising: alternately repeating the control method based on performing the removed body fluid weight measuring phase and based on performing a feed weight measuring phase, said feed weight measuring phase consisting of: a third phase of opening each of said first, second and third shutoff valves whereby said dialysate reservoir container and said replacement fluid reservoir container are filled with individual fluids while at the same time discharging a fluid from said drain reservoir container; and a fourth phase of controlling said apparatus by closing only the first shutoff valve and the second shutoff valve, and acquiring a change in total fluid weight in said dialysate reservoir container, said replacement fluid reservoir container, and said drain reservoir container from information provided by said weightmeter so as to calculate a feed weight which is the sum of the weight of replacement fluid and the weight of the dialysate, wherein said control unit controls the flow rate of at least one of said dialysate transfer pump, said replacement fluid transfer pump and said drain transfer pump such that a desired feed weight can be obtained during the fourth phase. 9. A blood purifying apparatus comprising a dialysate feed means, a replacement fluid feed means, a drain means, a blood purifying device, and a blood circulation path consisting of a blood drawing line and a blood retransfusing line, wherein: said dialysate feed means comprises: a dialysate transfer line of which one end is connected to said blood purifying device and the other end connected to a dialysate reservoir unit; a dialysate transfer pump disposed in said line; a dialysate reservoir container connected to a dialysate branch line branching off on an inlet side of said dialysate transfer pump; and a first shutoff valve attached to said dialysate transfer line upstream of a branch portion; said replacement fluid feed means comprises: a replacement fluid feeding line of which one end is connected to said blood retransfusing line and the other end connected to a replacement fluid reservoir unit; a replacement fluid transfer pump disposed in said line; a replacement fluid reservoir container connected to a replacement fluid branch line branching off on an inlet side of said replacement fluid transfer pump; and a second shutoff valve attached to said replacement fluid transfer line upstream of a branch portion; said drain means comprises: a drain line of which one end is connected to said blood purifying device and the other end opened; a drain transfer pump disposed in said line; a drain reservoir container connected to a drain branch line branching off on an outlet side of said drain transfer pump; and a third shutoff valve attached to said drain transfer line downstream of a branch portion, wherein the dialysate reservoir container, the replacement fluid reservoir container and the drain reservoir container are each equipped with a fluid level sensor, said apparatus further comprising a weightmeter for weighing the dialysate reservoir container, the replacement fluid reservoir container and the drain reservoir container at once, and a control unit for controlling the opening and closing of said first, second and third shutoff valves and the pump flow rate of each of said dialysate transfer pump, said replacement fluid transfer pump and said drain transfer pump, wherein said control unit performs a feed weight measuring phase consisting of: a first phase in which each of said first, second and third shutoff valves is opened, whereby said dialysate reservoir container and said replacement fluid reservoir container are filled with individual fluids while at the same time a fluid is discharged from said drain reservoir container; and a second phase in which said apparatus is controlled with only the first shutoff valve and the second shutoff valve closed, and in which a change in the total fluid weight in said dialysate reservoir container, said replacement fluid reservoir container, and said drain reservoir container is acquired from information provided by said weightmeter so as to calculate a feed weight which is the sum of the weight of replacement fluid and the weight of the dialysate, wherein said control unit controls the flow rate of the dialysate transfer pump and the replacement fluid transfer pump such that a desired feed weight can be obtained during the second phase.
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