[특허]Human telomerase reverse transcriptase polypeptides

[미국특허] Human telomerase reverse transcriptase polypeptides 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61K-038/00 A61K-038/08
출원번호	UP-0877124 (2004-06-24)
등록번호	US-7622549 (2009-12-02)
우선권정보	WO-PCT/US97/17618(1997-10-01); WO-PCT/US97/17885(1997-10-01)
발명자 / 주소	Cech, Thomas R. Lingner, Joachim Nakamura, Toru Chapman, Karen B. Morin, Gregg B. Harley, Calvin B. Andrews, William H.
출원인 / 주소	Geron Corporation The Regents of the University of Colorado
대리인 / 주소	Townsend and Townsend and Crew LLP
인용정보	피인용 횟수 : 2 인용 특허 : 60

초록 ▼

The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.

대표청구항 ▼

What is claimed is: 1. An isolated immunogenic polypeptide that consists of 10 or more consecutive amino acids of SEQ. ID NO:2. 2. An isolated immunogenic polypeptide that consists of 8 or more consecutive amino acids of SEQ. ID NO:2. 3. A composition comprising an isolated polypeptide consisting of 8 or more consecutive amino acids of SEQ ID NO:2, wherein said composition elicits an adaptive immune response against human telomerase reverse transcriptase having the sequence of SEQ. ID NO:2. 4. A composition comprising an isolated polypeptide consisting of 10 or more consecutive amino acids of SEQ ID NO:2, wherein said composition elicits an adaptive immune response against human telomerase reverse transcriptase having the sequence of SEQ. ID NO:2.

이 특허에 인용된 특허 (60) 인용/피인용 타임라인 분석

Graham Frank L.,CAX ; Anton Martina,CAX ; Rudnicki Michael A.,CAX, Adenoviral vector system comprising Cre-loxP recombination.
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Graham Frank L.,CAX ; Bett Andrew,CAX ; Prevec Ludvik,CAX ; Haddara Wael M.,CAX, Adenovirus vectors for gene therapy.
상세보기
Graham Frank L.,CAX ; Anton Martina,CAX ; Bacchetti Silvia,CAX ; Wang Ping,CAX ; Rudnicki Michael A.,CAX ; Muller William J.,CAX, Adenoviruses for control of gene expression.
상세보기
Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Antibody to telomerase reverse transcriptase.
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Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin B.; Andrews, William H., Antisense compositions for detecting and inhibiting telomerase reverse transcriptase.
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Thomas R. Cech ; Joachim Lingner CH; Toru Nakamura ; Karen B. Chapman ; Gregg B. Morin ; Calvin B. Harley ; William H. Andrews, Antisense compositions for detecting and inhibiting telomerase reverse transcriptase.
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Tsuchiya, Masayuki; Yoshida, Kenji, CRT-1 gene having reverse transcriptase motif.
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Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin B.; Andrews, William H., Cells immortalized with telomerase reverse transcriptase for use in drug screening.
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Tom Henry K. (La Honda CA) Rowley Gerald L. (Cupertino CA), Concentrating zone method in heterogeneous immunoassays.
상세보기
Federico C. A. Gaeta, Dendritic cell vaccine containing telomerase reverse transcriptase for the treament of cancer.
상세보기
Hagen Frederick S. (Seattle WA), Directional cloning.
상세보기
Ullman Edwin F. (Atherton CA) Schwarzberg Moshe (Palo Alto CA), Fluorescence quenching with immunological pairs in immunoassays.
상세보기
Kronick Melvyn N. (Palo Alto CA) Little William A. (Palo Alto CA), Fluorescent immunoassay employing total reflection for activation.
상세보기
Harrington Lea Anne,CAX ; Robinson Murray O., Genes encoding telomerase protein 1.
상세보기
Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin B.; Andrews, William H., Genes for human telomerase reverse transcriptase and telomerase variants.
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Collins Kathleen, Human telomerase.
상세보기
Collins Kathleen, Human telomerase.
상세보기
Cao Zhaodan, Human telomerase RNA interacting protein gene.
상세보기
Gregg B. Morin, Human telomerase catalytic subunit variants.
상세보기
Thomas R. Cech ; Joachim Lingner CH; Toru Nakamura ; Karen B. Chapman ; Gregg B. Morin ; Calvin B. Harley ; William H. Andrews, Human telomerase catalytic subunit: diagnostic and therapeutic methods.
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Hopp, Thomas P., Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity.
상세보기
Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Identifying and testing antisense oligonucleotides that inhibit telomerase reverse transcriptase.
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Morin,Gregg B., Inactive variants of the human telomerase catalytic subunit.
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Maggio Edward T. (Redwood City CA), Kit for carrying out chemically induced fluorescence immunoassay.
상세보기
Olson Maynard V. (St. Louis MO) Burke David T. (St. Louis MO), Large DNA cloning system based on yeast artificial chromosomes.
상세보기
Litman David J. (Palo Alto CA) Harel Zvi (Stanford CA) Ullman Edwin F. (Atherton CA), Macromolecular environment control in specific receptor assays.
상세보기
Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Mammalian cells that have increased proliferative capacity.
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Villeponteau Bryant (San Carlos CA) Feng Junli (San Carlos CA) Funk Walter (Union City CA) Andrews William H. (Richmond CA), Mammalian telomerase.
상세보기
Villeponteau Bryant ; Feng Junli ; Funk Walter ; Andrews William H., Mammalian telomerase.
상세보기
Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin; Andrews, William H., Method for detecting polynucleotides encoding telomerase.
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Smita K. Nair ; David J. Boczkowski ; Eli Gilboa, Method of identifying tumor antigens that elicit a T-cell response.
상세보기
Shay Jerry (Dallas TX) West Michael David (Belmont CA) Wright Woodring E. (Arlington TX), Methods for cancer diagnosis and prognosis.
상세보기
Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Methods for detecting nucleic acids encoding human telomerase reverse transcriptase.
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Weinrich, Scott L.; Atkinson, III, Edward M.; Lichtsteiner, Serge P.; Vasserot, Alain P.; Pruzan, Ronald A., Methods for purifying telomerase.
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Nair Smita K. ; Boczkowski David J. ; Gilboa Eli, Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA.
상세보기
Nair Smita K. ; Boczkowski David J. ; Gilboa Eli, Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA.
상세보기
Taylor Diane W. (Potomac MD), Monoclonal antibodies to a pan-malarial antigen.
상세보기
Morin, Gregg B.; Allsopp, Richard; DePinho, Ronald A.; Greenberg, Roger A., Mouse telomerase reverse transcriptase.
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Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Nucleic acids encoding human telomerase reverse transcriptase and related homologs.
상세보기
Mullis Kary B. (Kensington CA), Process for amplifying nucleic acid sequences.
상세보기
Mullis Kary B. (La Jolla CA) Erlich Henry A. (Oakland CA) Gelfand David H. (Oakland CA) Horn Glenn (Emeryville CA) Saiki Randall K. (Richmond CA), Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme.
상세보기
Mullis Kary B. (Kensington CA) Erlich Henry A. (Oakland CA) Arnheim Norman (Woodland Hills CA) Horn Glenn T. (Emeryville CA) Saiki Randall K. (Richmond CA) Scharf Stephen J. (Berkeley CA), Process for amplifying, detecting, and/or-cloning nucleic acid sequences.
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Morin, Gregg B.; Andrews, William H., Promoter for telomerase reverse transcriptase.
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Weinrich, Scott L.; Atkinson, III, Edward M.; Lichtsteiner, Serge P.; Vasserot, Alain P.; Pruzan, Ronald A., Purified telomerase.
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Weinrich Scott L. ; Atkinson ; III Edward M. ; Lichtsteiner Serge P. ; Vasserot Alain P. ; Pruzan Ronald A. ; Kealey James T., Purified telomerose.
상세보기
Cabilly Shmuel (Monrovia CA) Heyneker Herbert L. (Burlingame CA) Holmes William E. (Pacifica CA) Riggs Arthur D. (La Verne CA) Wetzel Ronald B. (San Francisco CA), Recombinant immunoglobin preparations.
상세보기
Diamond Paul (693 Somerville Ave. ; Apt. 4 Somerville MA 02143), Screening assay for inhibitors and activators of RNA and DNA-dependent nucleic acid polymerases.
상세보기
Cech Thomas R. ; Lingner Joachim,CHX, Telomerase.
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Cech Thomas R. ; Lingner Joachim,CHX ; Nakamura Toru ; Chapman Karen B. ; Morin Gregg B. ; Harley Calvin B. ; Andrews William H., Telomerase.
상세보기
Cech Thomas R. ; Nakamura Toru, Telomerase.
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Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin B.; Andrews, William H., Telomerase.
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Cech,Thomas R.; Lingner,Joachim; Nakamura,Toru; Chapman,Karen B.; Morin,Gregg B.; Harley,Calvin B.; Andrews,William H., Telomerase.
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Cech Thomas R. ; Lingner Joachim, Telomerase catalytic subunit.
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Morin, Gregg B.; Lichtsteiner, Serge P.; Vasserot, Alain P.; Adams, Robert R.; Andrews, William H., Telomerase promoter driving expression of therapeutic gene sequences.
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Morin,Gregg B.; Lichtsteiner,Serge; Vasserot,Alain; Adams,Robert; Andrews,William H., Telomerase promoters sequences for screening telomerase modulators.
상세보기
West Michael D. (Belmont CA) Shay Jerry (Dallas TX) Wright Woodring (Arlington TX), Therapy and diagnosis of conditions related to telomere length and/or telomerase activity.
상세보기
Jiang,Xu Rong; Chiu,Choy Pik; Harley,Calvin B., Treatment for wounds.
상세보기
Weinrich, Scott L.; Atkinson, III, Edward M.; Lichtsteiner, Serge P.; Vasserot, Alain P.; Pruzan, Ronald A., Using purified telomerase to identify telomerase activators and inhibitors.
상세보기
Kilian, Andrzej; Bowtell, David, Vertebrate telomerase genes and proteins and uses thereof.
상세보기
Kilian, Andrzej; Bowtell, David, Vertebrate telomerase genes and proteins and uses thereof.
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이 특허를 인용한 특허 (2) 인용/피인용 타임라인 분석

Binder, Joseph John; Cockle, Paul Jason; Falconer, Derek John; Guru, Siradanahalli; Jooss, Karin Ute; Martinic, Marianne Marcela Andrea; Wills, Kenneth Nelson; Cho, Helen Kim, Cancer vaccines.
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Cech, Thomas R.; Lingner, Joachim; Nakamura, Toru M.; Chapman, Karen B.; Morin, Gregg B.; Harley, Calvin B.; Andrews, William H., Method for eliciting an immune response to human telomerase reverse transcriptase.
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[미국특허] Human telomerase reverse transcriptase polypeptides 원문보기