초록 ▼

A system for automation of laboratory analyzers that utilizes radio frequency identification (RFID) tags and radio frequency identification (RFID) readers to identify containers and vessels, and the contents thereof, that are employed in the system. Radio frequency identification tags, conforming to

A system for automation of laboratory analyzers that utilizes radio frequency identification (RFID) tags and radio frequency identification (RFID) readers to identify containers and vessels, and the contents thereof, that are employed in the system. Radio frequency identification tags, conforming to the guidelines of ISO 14443 or ISO 15693 or ISO 18000, are positioned on the items of interest, such as, for example, reagent containers, sample containers, and microplates. These tags can be read by and written to by either a moving antenna of a RFID reader or a stationary antenna of a RFID reader. Reading of RFID tags and writing to RFID tags are controlled by software.

대표청구항 ▼

What is claimed is: 1. A system comprising a plurality of containers, each of which container has a top and a bottom and contains a liquid, each of which container has a radio frequency identification tag attached thereto on the bottom thereof, the system further including at least one movable radi

What is claimed is: 1. A system comprising a plurality of containers, each of which container has a top and a bottom and contains a liquid, each of which container has a radio frequency identification tag attached thereto on the bottom thereof, the system further including at least one movable radio frequency identification reader, wherein the movable radio frequency identification reader is movable to a position below the radio frequency identification tag, whereby information from the radio frequency identification tag is read with an amount of noise and interference from nearby radio frequency identification tags on other containers insufficient to adversely affect the integrity of the data read by a radio frequency identification reader. 2. The system of claim 1, further including a transmission sub-system for enabling the at least one reader to move within the system. 3. The system of claim 1, further including at least one analysis station comprising apparatus for automated analysis of a biological sample from a patient. 4. The system of claim 3, wherein the at least one container is transportable to a location in the system, and said system further includes a sub-system for tracking the location of the at least one container in the system. 5. The system of claim 3, wherein the at least one analysis station comprises an automated immunoassay instrument. 6. The system of claim 3, wherein the at least one analysis station comprises an automated clinical chemistry instrument. 7. The system of claim 3, wherein the at least one analysis station comprises an automated hematology instrument. 8. The system of claim 3, wherein the at least one analysis station comprises an automated nucleic acid analyzer instrument. 9. The system of claim 8, wherein the automated nucleic acid analyzer instrument is selected from the group consisting of an automated nucleic acid microarray analyzer instrument and an automated nucleic acid amplification analyzer instrument. 10. The system of claim 3, wherein the at least one analysis station comprises an automated slide processing instrument. 11. The system of claim 3, wherein the at least one analysis station comprises an automated protein analyzer instrument. 12. The system of claim 3, further comprising an automated sample processing station. 13. The system of claim 12, wherein the automated sample processing station comprises apparatus for extraction of nucleic acid from a biological sample. 14. The system of claim 3, comprising a plurality of analysis stations, wherein each of said plurality of analysis stations comprises apparatus for the automated analysis of a biological sample. 15. The system of claim 14, comprising at least two analysis stations, wherein said at least two analysis stations are selected from the group consisting of automated immunoassay instruments, automated hematology instruments, automated nucleic acid analyzer instruments, automated slide processing instruments, and automated protein analyzer instruments. 16. The system of claim 15, further comprising an automated sample processing station. 17. A system comprising a plurality of containers, each of which container has a top and a bottom and contains a liquid, each of which container has a radio frequency identification tag attached thereto on the bottom thereof, the system further including at least one radio frequency identification reader, said at least one radio frequency identification reader having a plurality of stationary antennas, wherein each of the plurality of containers is movable to a position above one of the plurality of radio frequency identification antennas of the at least one radio frequency identification reader, whereby information from the radio frequency identification tag is read with an amount of noise and interference from nearby radio frequency identification tags on other containers insufficient to adversely affect the integrity of the data read by an antenna of said at least one radio frequency identification. 18. The system of claim 17, wherein each of said plurality of stationary radio frequency identification antennas of said radio frequency identification reader is a trace on a printed circuit board. 19. The system of claim 17, wherein each radio frequency identification tag has an antenna having a length, the length of each antenna determining the relationship with the radio frequency used. 20. The system of claim 17, wherein the radio frequency identification tags are encapsulated. 21. The system of claim 17, wherein the antennas of the antennas of the at least one radio frequency identification reader are positioned in an array characterized by Cartesian coordinates. 22. The system of claim 17, further including at least one analysis station comprising apparatus for automated analysis of a biological sample from a patient. 23. The system of claim 22, wherein the at least one container is transportable to a location in the system, and said system further includes a sub-system for tracking the location of the at least one container in the system. 24. The system of claim 22, wherein the at least one analysis station comprises an automated immunoassay instrument. 25. The system of claim 22, wherein the at least one analysis station comprises an automated clinical chemistry instrument. 26. The system of claim 22, wherein the at least one analysis station comprises an automated hematology instrument. 27. The system of claim 22, wherein the at least one analysis station comprises an automated nucleic acid analyzer instrument. 28. The system of claim 27, wherein the automated nucleic acid analyzer instrument is selected from the group consisting of an automated nucleic acid microarray analyzer instrument and an automated nucleic acid amplification analyzer instrument. 29. The system of claim 22, wherein the at least one analysis station comprises an automated slide processing instrument. 30. The system of claim 22, wherein the at least one analysis station comprises an automated protein analyzer instrument. 31. The system of claim 22, further comprising an automated sample processing station. 32. The system of claim 31, wherein the automated sample processing station comprises apparatus for extraction of nucleic acid from a biological sample. 33. The system of claim 22, comprising a plurality of analysis stations, wherein each of said plurality of analysis stations comprises apparatus for the automated analysis of a biological sample. 34. The system of claim 33, comprising at least two analysis stations, wherein said at least two analysis stations are selected from the group consisting of automated immunoassay instruments, automated hematology instruments, automated nucleic acid analyzer instruments, automated slide processing instruments, and automated protein analyzer instruments. 35. The system of claim 34, further comprising an automated sample processing station. 36. A method of determining whether a biological sample is acceptable for the analysis thereof in a system comprising an automated analyzer, the method comprising the steps of: (a) providing a liquid biological sample in a container having a top and a bottom, the radio frequency identification tag positioned on the bottom of the container; (b) interrogating a radio frequency identification tag on said container containing said liquid biological sample to obtain information therefrom relating to storage information wherein said radio frequency identification tag is interrogated by a radio frequency identification reader, wherein said radio frequency identification reader is in a position below the container so that information from the radio frequency identification tag is read with an amount of noise and interference from nearby radio frequency identification tags on other containers that are insufficient to adversely affect the integrity of the data read by the radio frequency identification reader; (c) comparing the storage information to a set of acceptable storage conditions; and (d) rejecting or accepting the sample container for analysis of the sample, based on the comparing step performed in (c), wherein steps (b), (c) and (d) are automatically performed by an automated analyzer system. 37. The method of claim 36, further comprising the step of performing at least one analysis of the biological sample. 38. The method of claim 37, wherein the analysis is performed with at least one instrument selected from the group consisting of automated immunoassay instruments, automated clinical chemistry instruments, automated hematology instruments, automated nucleic acid analyzer instruments, automated slide processing instruments, and automated protein analyzer instruments. 39. The method of claim 36, further comprising updating an information database to specify the location of each sample container present in the automated analyzer system. 40. The method of claim 36, further comprising updating the information database to specify the quantity of liquid removed from each sample container present in the automated analyzer system. 41. A method of determining whether a reagent is acceptable for the analysis of a biological sample in an automated analyzer system, the method comprising the steps of: (a) providing a liquid reagent in a container having a top and a bottom, a radio frequency identification tag attached to the bottom of the container, wherein the radio frequency identification tag comprises an information device that contains information on storage conditions to which the reagent container has been exposed; (b) interrogating a radio frequency identification tag on said container containing said liquid reagent to determine the information on storage conditions for the at least one reagent container wherein said radio frequency identification tag is interrogated by a radio frequency identification reader, wherein said radio frequency identification reader is in a position below the container so that information from the radio frequency identification tag is read with an amount of noise and interference from nearby radio frequency identification tags on other containers that are insufficient to adversely affect the integrity of the data read by the radio frequency identification reader; (c) comparing the information on storage conditions to a set of acceptable storage conditions; and (d) rejecting or accepting the reagent container for use in an automated analyzer system, based on the comparing step performed in step (c), wherein steps (b), (c) and (d) are automatically performed by an automated analyzer system. 42. The method of 41, further comprising the step of performing at least one automated analysis of the sample using at least one reagent container determined to be acceptable for use. 43. The method of claim 41, wherein the automated analysis is performed with at least one instrument selected from the group consisting of automated immunoassay instruments, automated clinical chemistry instruments, automated hematology instruments, automated nucleic acid analyzer instruments, automated slide processing instruments, and automated protein analyzer instruments. 44. The method of claim 41, further comprising the step of updating an information database to specify location of each reagent container present in the automated analyzer system. 45. The method of claim 41, further comprising the step of updating an information database to specify the quantity of sample removed from each sample container present in the automated analyzer system.