IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
UP-0297936
(2001-06-20)
|
등록번호 |
US-7718438
(2010-06-10)
|
우선권정보 |
JP-2000-184393(2000-06-20) |
국제출원번호 |
PCT/JP2001/005274
(2001-06-20)
|
§371/§102 date |
20021220
(20021220)
|
국제공개번호 |
WO01/098781
(2001-12-27)
|
발명자
/ 주소 |
- Takahashi, Atsushi
- Akita, Takashi
- Itou, Chiho
- Miyauchi, Haruko
- Murase, Kei
|
출원인 / 주소 |
- Mitsubishi Rayon Co., Ltd.
|
대리인 / 주소 |
Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
|
인용정보 |
피인용 횟수 :
0 인용 특허 :
7 |
초록
▼
A microarray obtainable by slicing a block comprising a plurality of linear bodies or through-holes which carry an organism-related substance, in a direction intersecting the longitudinal direction of the linear bodies or through-holes, wherein the linear body and/or block comprise a substance that
A microarray obtainable by slicing a block comprising a plurality of linear bodies or through-holes which carry an organism-related substance, in a direction intersecting the longitudinal direction of the linear bodies or through-holes, wherein the linear body and/or block comprise a substance that reduces the self-fluorescence thereof.
대표청구항
▼
The invention claimed is: 1. A method of producing a microarray which comprises: forming a block which comprises carbon black, fully dispersed throughout the block, that increases a hardness of the block; after the forming the block, forming a plurality of through-holes in the block via a drill or
The invention claimed is: 1. A method of producing a microarray which comprises: forming a block which comprises carbon black, fully dispersed throughout the block, that increases a hardness of the block; after the forming the block, forming a plurality of through-holes in the block via a drill or a laser; allowing the through-holes to carry a biological substance; allowing the block to harden; and slicing the block in a direction intersecting the longitudinal direction of the through-holes, wherein the biological substance is selected from a group including (a) a nucleic acid, an amino acid, a saccharide, or a lipid, (b) a polymeric substance including at least one substance in (a), and (c) a substance that interacts with a substance in (a) or (b). 2. A method of producing a microarray which comprises: preparing a block by overlapping perforated boards having a plurality of holes, passing linear bodies carrying a biological substance through each of the plurality of holes in the perforated boards, opening an interval between the perforated boards, and pouring a resin into the interval to immobilize the linear bodies, the resin comprising carbon black fully dispersed throughout the resin, wherein the carbon black increases a hardness of the resin; allowing the block including the resin to harden; and slicing the block in a direction intersecting the longitudinal direction of the linear bodies, wherein the biological substance is selected from a group including (a) a nucleic acid, an amino acid, a saccharide, or a lipid, (b) a polymeric substance including at least one substance in (a), and (c) a substance that interacts with a substance in (a) or (b). 3. A method of producing a microarray which comprises: preparing a block by overlapping perforated boards having a plurality of holes, passing linear bodies through each of the plurality of holes in the perforated boards, opening an interval between the perforated boards, and pouring a resin into the interval to immobilize the linear bodies, the resin comprising carbon black fully dispersed throughout the resin, wherein the carbon black increases a hardness of the resin; allowing each of the linear bodies to carry a biological substance, allowing the block including the resin to harden; and slicing the block in a direction intersecting the longitudinal direction of the linear bodies, wherein the biological substance is selected from a group including (a) a nucleic acid, an amino acid, a saccharide, or a lipid, (b) a polymeric substance including at least one substance in (a), and (c) a substance that interacts with a substance in (a) or (b). 4. The method of producing as in claim 2, wherein the allowing the through-holes to carry the biological substance includes carrying the biological substance via a gel. 5. The method of producing as in claim 2, further comprising: soaking a bundle of linear bodies with a biological substance; and baking the bundle of linear bodies with an ultraviolet light. 6. The method of producing as in claim 3, wherein the linear bodies are hollow fibers, and the allowing each of the linear bodies to carry the biological substance includes introducing the biological substance to a hollow part of the hollow fibers by filling the hollow part with a high molecular polymer including the biological substance. 7. The method of production as in any one of claims 1-3, wherein the carbon black content is 0.5-10% by mass.
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