최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | UP-0674220 (2007-02-13) |
등록번호 | US-7731729 (2010-06-29) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 1 인용 특허 : 940 |
A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the penetrating member driver. A support
A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the penetrating member driver. A support is provided with a plurality of openings. Each opening receives a penetrating member.
What is claimed is: 1. A tissue penetration device, comprising: a penetrating member driver; a cartridge; a plurality of penetrating members integrated with the cartridge, each of a penetrating member coupled to the penetrating member driver when advanced along a path into a tissue target; and a su
What is claimed is: 1. A tissue penetration device, comprising: a penetrating member driver; a cartridge; a plurality of penetrating members integrated with the cartridge, each of a penetrating member coupled to the penetrating member driver when advanced along a path into a tissue target; and a support with a plurality of openings, each opening receiving a penetrating member, each tip of a penetrating member being uncovered during launch of a penetrating member by the penetrating driver member; and a penetrating member position sensor coupled to the plurality of penetrating members and to a processor, the penetrating member position sensor and the processor measuring a distance from an initialization point to a point of contact of a penetrating member to a target tissue surface, the penetrating member being retracted by the penetrating member driver to the initialization point with a distance to the target tissue being measured and a depth of penetration of the penetrating member determined. 2. The system of claim 1, further comprising: a penetrating member sensor coupled to the plurality of penetrating members, the penetrating member sensor configured to provide information relative to a depth of penetration of a penetrating member through a skin surface. 3. The system of claim 2, wherein the depth of penetration is 100 to 2500 microns. 4. The system of claim 2, wherein the depth of penetration is 500 to 750 microns. 5. The system of claim 2, wherein the penetrating member sensor is further configured to provide an indication of velocity of a penetrating member. 6. The system of claim 2, further comprising: a second penetrating member sensor configured to provide an indication of velocity of a penetrating member. 7. The system of claim 2, further comprising: a feedback loop coupled to the penetrating member sensor. 8. The system of claim 2, wherein the penetrating member driver is an electric drive force member. 9. The system of claim 2, wherein the penetrating member driver is a voice coil drive force generator. 10. The system of claim 2, wherein the penetrating member sensor is coupled to a processor with control instructions for the penetrating member driver. 11. The system of claim 10, wherein the processor includes a memory for storage and retrieval of a set of penetrating member profiles utilized with the penetrating member driver. 12. The system of claim 10, wherein the processor is utilized to monitor position and speed of a penetrating member as the penetrating member moves in a first direction. 13. The system of claim 10, wherein the processor is utilized to adjust an application of force to a penetrating member to achieve a desired speed of the penetrating member. 14. The system of claim 10, wherein the processor is utilized to adjust an application of force to a penetrating member when the penetrating member contacts a target tissue so that the penetrating member penetrates the target tissue within a desired range of speed. 15. The system of claim 10, wherein the processor is utilized to monitor position and speed of a penetrating member as the penetrating member moves in the first direction toward a target tissue, wherein the application of a launching force to the penetrating member is controlled based on position and speed of the penetrating member. 16. The system of claim 15, wherein a speed of a penetrating member in the first direction is the range of 0.05 to 60 m/sec. 17. The system of claim 15, wherein a speed of a penetrating member in the first direction is the range of 0.1 to 20.0 m/sec. 18. The system of claim 15, wherein a speed of a penetrating member in the first direction is the range of 1.0 to 10.0 m/sec. 19. The system of claim 15, wherein a speed of a penetrating member in the first direction is the range of 3.0 to 8.0 m/sec. 20. The system of claim 15, wherein a dwell time of the penetrating member in the target tissue below a skin surface is in the range of 1 microsecond to 2 seconds. 21. The system of claim 10, wherein the processor is utilized to control a withdraw force to the penetrating member so that the penetrating member moves in a second direction away from the target tissue. 22. The system of claim 21, wherein in the first direction the penetrating member moves toward the target tissue at a speed that is different than a speed at which the penetrating member moves away from the target tissue. 23. The system of claim 21, wherein in the first direction the penetrating member moves toward the target tissue at a speed that is greater than a speed at which the penetrating member moves away from the target tissue. 24. The system of claim 2, wherein a dwell time of the penetrating member in the target tissue below a skin surface is in the range of 500 milliseconds to 1.5 second. 25. The system of claim 2, wherein a dwell time of the penetrating member in the target tissue below a skin surface is in the range of 100 milliseconds to 1 second. 26. The system of claim 2, wherein the penetrating member sensor includes a capacitive incremental encoder. 27. The system of claim 2, wherein the penetrating member sensor includes an incremental encoder. 28. The system of claim 2, wherein the penetrating member sensor includes an optical encoder. 29. The system of claim 2, wherein the penetrating member sensor includes an interference encoder. 30. The system of claim 1, further comprising: an analyte detecting member. 31. The system of claim 1, further comprising: a plurality of analyte detecting members each coupled to a penetrating member. 32. The system of claim 1, further comprising: a sample chamber with an opening for transport of a body fluid into the sample chamber, the sample chamber being sized to receive no more than 1.0 μL of the body fluid. 33. The system of claim 32, wherein each of a penetrating member and an associated sample chamber have a combined packing density of no more than 1.0 cm3. 34. The system of claim 32, wherein each of a penetrating member and an associated sample chamber have a combined packing density of no more than 0.75 cm3. 35. The system of claim 32, wherein each of a penetrating member and an associated sample chamber have a combined packing density of no more than 0.5 cm3. 36. The system of claim 32, wherein each of a penetrating member and an associated sample chamber have a combined packing density of no more than 0.25 cm3. 37. The system of claim 32, wherein each of a penetrating member and an associated sample chamber have a combined packing density of no more than 0.1 cm3. 38. The system of claim 1, further comprising: a sample chamber with an opening for transport of a body fluid into the sample chamber, the sample chamber being sized to receive no more than 0.75 μL of the body fluid. 39. The system of claim 1, further comprising: a sample chamber with an opening for transport of a body fluid into the sample chamber, the sample chamber being sized to receive no more than 0.5 μL of the body fluid. 40. The system of claim 1, further comprising: a sample chamber with an opening for transport of a body fluid into the sample chamber, the sample chamber being sized to receive no more than 0.25 μL of the body fluid. 41. The system of claim 1, further comprising: a sample chamber with an opening for transport of a body fluid into the sample chamber, the sample chamber being sized to receive no more than 0.1 μL of the body fluid. 42. The system of claim 1, further comprising: an analyte detecting member coupled to a sample chamber, the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 1 μL of a body fluid disposed in the sample chamber. 43. The system of claim 1, further comprising: an analyte detecting member coupled to a sample chamber, the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 0.75 μL of a body fluid disposed in the sample chamber. 44. The system of claim 1, further comprising: an analyte detecting member coupled to a sample chamber, the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 0.5 μL of a body fluid disposed in the sample chamber. 45. The system of claim 1, further comprising: an analyte detecting member coupled to a sample chamber, the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 0.25 μL of a body fluid disposed in the sample chamber. 46. The system of claim 1, further comprising: an analyte detecting member coupled to a sample chamber, the analyte detecting member being configured to determine a concentration of an analyte in a body fluid using a sample that does not exceed a volume of 0.1 μL of a body fluid disposed in the sample chamber. 47. The system of claim 1, wherein each of a penetrating of the plurality of penetrating members has a packing density of no more than 1.0 cm3/penetrating member. 48. The system of claim 1, wherein each of a penetrating member of the plurality of penetrating members has a packing density of no more than 0.75 cm3/penetrating member. 49. The system of claim 1, wherein the each of a penetrating member of the plurality of penetrating members has a packing density of no more than 0.5 cm3/penetrating member. 50. The system of claim 1, wherein each of a penetrating member of the plurality of penetrating members has a packing density of no more than 0.25 cm3/penetrating member. 51. The system of claim 1, wherein each of a penetrating member of the plurality of penetrating members has a packing density of no more than 0.1 cm3/penetrating member. 52. The system of claim 1, further comprising: a tissue stabilizer device coupled to the housing. 53. The system of claim 52, wherein the tissue stabilizer device is configured to enhance fluid flow from a target tissue. 54. The system of claim 52, wherein the tissue stabilizer device creates a stretching of a skin surface. 55. The system of claim 52, wherein the tissue stabilizer device includes a plurality of protrusions. 56. The system of claim 52, wherein the tissue stabilizer device applies a vacuum to a target tissue. 57. The system of claim 52, wherein the tissue stabilizer device is configured to apply a force to a target tissue and cause the target tissue to press in an inward direction relative to the housing member. 58. The system of claim 52, wherein the tissue stabilizing member applies a stimulation to a target tissue.
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