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[미국특허] Compositions for treating amyloid associated diseases 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/405
출원번호 UP-0660522 (2005-08-18)
등록번호 US-7732479 (2010-06-29)
국제출원번호 PCT/IL2005/000902 (2005-08-18)
§371/§102 date 20071010 (20071010)
국제공개번호 WO06/018850 (2006-02-23)
발명자 / 주소
  • Gazit, Ehud
  • Cohen, Tomer
출원인 / 주소
  • Tel Aviv University Future Technology Development L.P.
인용정보 피인용 횟수 : 15  인용 특허 : 50

초록

Indole derivatives, compositions including same, and methods utilizing same for the treatment of amyloid associated diseases, such as type II diabetes mellitus, Alzheimer's dementia or diseases, systemic and localized amyloidosis, and prion-related encephalopathies are provided.

대표청구항 ▼

What is claimed is: 1. A method of treating Alzheimer's disease in a subject, the method comprising administering to a subject in need thereof, a therapeutically effective amount of a compound selected from the group consisting of 3-hydroxyindole and 4-hydroxyindole and thereby treating the Alzheim

이 특허에 인용된 특허 (50) 인용/피인용 타임라인 분석

  1. Rubenstein Kenneth Edward (Palo Alto CA) Leute Richard K. (Sunnyvale CA), Antibody steric hindrance immunoassay with two antibodies.
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  10. Steiner Solomon (Mt. Kisco NY) Rosen Robert (Rochester NY), Delivery systems for pharmacological agents encapsulated with proteinoids.
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  12. Berger Dieter (Viernheim DEX) Frey Gnter (Ludwigshafen DEX) Kuhr Manfred (Mannheim DEX) Werner Wolfgang (Mannheim DEX), Diagnostic agents for the detection of leukocytes in body fluids.
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  16. Batcho Andrew David (Belleville NJ) Leimgruber Willy (Montclair NJ), Intermediates for indoles.
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  20. Weiner David B. (Merion Station PA) Ugen Kenneth E. (Philadelphia PA) Williams William V. (Havertown PA), Methods and compositions for diagnosing and treating certain HIV infected patients.
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  25. Afroditi Kapurniotu DE; Jurgen Bernhagen DE; Herwig Brunner DE, Peptides used as agonists and/or inhibitors of amyloid formation and cytotoxicity and also for use in alzheimer's disease, in type II diabetes mellitus and in spongiform encephalophathies.
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  26. Takle, Garry B.; Goldberg, Allan R.; George, Shaji T., Phenotypic conversion of cells mediated by external guide sequences.
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  27. Kihara Naoko (Matsudo JPX) Yuasa Fumihiko (Tokyo JPX) Ushirogouchi Tohru (Yokohama JPX) Tada Tsukasa (Tokyo JPX) Sasaki Osamu (Sagamihara JPX) Naito Takuya (Tokyo JPX) Saito Satoshi (Yokohama JPX), Potosensitive composition and method of forming a pattern using the same.
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  44. Lonberg Nils (San Francisco CA) Kay Robert M. (San Francisco CA), Transgenic non-human animals capable of producing heterologous antibodies of various isotypes.
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이 특허를 인용한 특허 (15) 인용/피인용 타임라인 분석

  1. Gazit, Ehud; Amir, Yaniv; Buzhansky, Ludmila; Abel, Ulrich; Frydman-Marom, Anat, Dipeptide analogs for treating conditions associated with amyloid fibril formation.
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  2. Gazit, Ehud; Amir, Yaniv; Buzhansky, Ludmila; Abel, Ulrich; Frydman-Marom, Anat, Dipeptide analogs for treating conditions associated with amyloid fibril formation.
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  3. Gazit, Ehud, Method of screening for compounds that disaggregate amyloid aggregates.
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  4. Gazit, Ehud, Peptides and methods using same for diagnosis and treatment of amyloid-associated disease.
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  5. Gazit, Ehud, Peptides and methods using same for diagnosis and treatment of amyloid-associated disease.
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  6. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonist serlopitant in pruritus.
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  7. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonist serlopitant in pruritus.
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  8. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonist serlopitant in pruritus.
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  9. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonist serlopitant in pruritus.
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  10. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonists in pruritus.
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  11. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonists in pruritus.
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  12. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonists in pruritus.
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  13. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonists in pruritus.
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  14. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonists in pruritus.
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  15. Zhang, Xiaoming; Schnipper, Edward F.; Perlman, Andrew J.; Larrick, James W., Use of NK-1 receptor antagonists in pruritus.
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