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A method for forming a ceramic article useful as a bone substitute and having an outer surface defining a shape having a bulk volume and having open, interconnecting openings extending throughout the volume and opening through the surface, includes, providing an organic open-pore structure, coating

A method for forming a ceramic article useful as a bone substitute and having an outer surface defining a shape having a bulk volume and having open, interconnecting openings extending throughout the volume and opening through the surface, includes, providing an organic open-pore structure, coating surface of pores of the structure with a ceramic slip, pyrolyzing the organic structure to leave a ceramic structure having struts defining a plurality of interconnecting interstices, and providing within the interstices a porous osteoconductive composition exposed to the interconnecting openings. In a preferred embodiment, the ceramic slip includes a strong, supportive ceramic material and a separate osteoconductive material.

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What is claimed is: 1. A method of forming a ceramic article useful as a bone substitute and having an outer surface defining a shape having a bulk volume and having open, interconnecting openings extending throughout said volume and opening through said surface, the method comprising providing an

What is claimed is: 1. A method of forming a ceramic article useful as a bone substitute and having an outer surface defining a shape having a bulk volume and having open, interconnecting openings extending throughout said volume and opening through said surface, the method comprising providing an organic open-pore structure, coating surfaces of pores of the structure with a ceramic slip comprising zirconia, a binder, a solvent, fibers and/or whiskers, and hydroxyapatite, wherein the hydroxyapatite is present in an amount of up to about 50 volume percent based on the total volume of zirconia and hydroxyapatite, pyrolyzing the organic structure to leave a ceramic structure having struts defining a plurality of interconnecting interstices, and sintering the ceramic structure, said osteoconductive material being exposed to said interconnecting openings. 2. A method of claim 1, including the step of shaping said organic open-pore structure to a predetermined configuration before coating the pores thereof with said ceramic slip. 3. A method of claim 1, including the step of shaping said organic open-pore structure to a predetermined configuration after coating the pores thereof with said ceramic slip. 4. A method of claim 1 including the step of inserting a calcium phosphate bone cement into said openings. 5. A method of claim 1, wherein the hydroxyapatite is present in an amount of about 10 to about 25 volume percent based on the total volume of the zirconia and the hydroxyapatite. 6. A method of claim 1, further comprising the step of sintering the ceramic structure to a second, denser structural element. 7. A method of claim 1, wherein the fibers and/or whiskers comprise a material selected from the group consisting of glass, metal, and ceramic. 8. A method of claim 7, wherein the ceramic is selected from the group consisting of silicon nitride, silicon carbide, zirconia, alumina, and carbon. 9. A method of claim 1, wherein the length of the fibers and/or whiskers is from about 0.1 to about 100 microns. 10. A method of claim 1, further comprising contacting the struts with a porous osteoconductive coating either before or after said sintering step. 11. A method of claim 10, wherein the porous osteoconductive composition comprises an osteoconductive material selected from the group consisting of collagen, calcium phosphates, bone morphogenetic proteins, demineralized bone matrix, transforming growth factors, and osteoblast cells. 12. A method of claim 10, wherein the porous osteoconductive coating comprises hydroxyapatite. 13. A method of claim 1, wherein the ceramic structure comprises interstices having a size range of about 50 μm to about 1000 μm and a void volume of at least about 30%. 14. A method of claim 1, wherein the zirconia is yttria-stabilized zirconia. 15. A method of producing a rigid reticulated article, comprising: (a) providing a first dispersion of a metal or ceramic powder, a binder comprising a polyacrylate emulsion that polymerizes upon drying, and a solvent; (b) providing a reticulated substrate which has open, interconnected porosity; (c) contacting the reticulated substrate with the first dispersion to coat the substrate with the dispersion; (d) drying the coated reticulated substrate; (e) optionally contacting the reticulated substrate with one or more additional dispersions to form one or more additional coatings wherein the one or more additional coatings are the same or different from each other and the first coating; (f) drying the additional coating between the steps of contacting; (g) heating the coated reticulated substrate at a time and temperature sufficient to pyrolyze any organic components; (h) sintering to form a ceramic or metal or composite reticulated article; and further comprising the step of adding fibers and/or whiskers to at least one of the first dispersion and the one or more additional dispersions. 16. A method of claim 15, wherein the fibers and/or whiskers comprise a material selected from the group consisting of glass, metal, and ceramic. 17. A method of claim 16, wherein the ceramic is selected from the group consisting of silicon nitride, silicon carbide, zirconia, alumina, and carbon. 18. A method of claim 15, wherein the fibers and/or whiskers are added to more than one of the first dispersion and the one or more additional dispersions, and wherein the fibers and/or whiskers may comprise the same or different material. 19. A method of claim 15, wherein the length of the fibers and/or whiskers is from about 0.1 to about 100 microns. 20. A method of claim 15, wherein the volume fraction of binder is at least about 25 vol. % based on the entire volume of the solid components of the dispersion following drying.