Aerosol generating devices and methods for generating aerosols having controlled particle sizes
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
F24F-003/14
F23D-011/00
H05B-003/00
A61M-015/00
출원번호
UP-0140984
(2005-06-01)
등록번호
US-7743766
(2010-07-19)
발명자
/ 주소
Gupta, Rajiv
McRae, Douglas D.
Cox, Kenneth A.
Nichols, Walter A.
출원인 / 주소
Philip Morris USA Inc.
대리인 / 주소
Buchanan Ingersoll & Rooney PC
인용정보
피인용 횟수 :
4인용 특허 :
31
초록
An aerosol generating device includes a housing, a heater and an optional mouthpiece. The heater volatilizes liquid within a flow passage and forms an aerosol in the mouthpiece. An aerosol confinement sleeve is disposed to control the size distribution of the aerosol.
대표청구항▼
What is claimed is: 1. A method for generating an aerosol, comprising: supplying liquid to a capillary sized flow passage having an outlet; heating the capillary sized flow passage so as to volatilize at least some of the liquid in the capillary sized flow passage; and directing the volatilized liq
What is claimed is: 1. A method for generating an aerosol, comprising: supplying liquid to a capillary sized flow passage having an outlet; heating the capillary sized flow passage so as to volatilize at least some of the liquid in the capillary sized flow passage; and directing the volatilized liquid into a confined air space enclosed within an aerosol confinement sleeve having a volume of about 0.05 in3 to about 0.4 in3. 2. The method of claim 1, further comprising forming an aerosol by directing the volatilized liquid out from the confined air space, wherein the aerosol formed has an MMAD (mass median aerosol diameter) of 0.2 to 0.5 μm or 1 to 2 μm. 3. The method of claim 1, wherein the directing the volatilized liquid into a confined air space comprises directing the volatilized liquid into a hollow cylinder. 4. The method of claim 1, wherein the directing the volatilized liquid into a confined air space comprises directing the volatilized liquid directly from the capillary sized flow passage into the confined air space, wherein an outer region of a body surrounding the capillary sized flow passage is in contact with an inner region of the confined air space to form a contiguous flow passage. 5. The method of claim 1, wherein the capillary sized flow passage is the lumen of a capillary tube, the method further comprising thermally insulating the capillary sized flow passage with a cylindrical body of a thermally insulating material in a surrounding relationship to the capillary tube. 6. The method of claim 1, wherein the directing the volatilized liquid into a confined air space causes condensation of at least some of the volatilized liquid within the confined air space. 7. The method of claim 1, wherein during the directing the volatilized liquid into a confined air space, air is prevented from flowing into the confined air space except at an outlet of the confinement sleeve. 8. The method of claim 1, wherein the directing the volatilized liquid into a confined air space comprises directing the volatilized liquid into the aerosol confinement sleeve with a length from about ⅛ inch to about 2 inches, a largest transverse dimension from about ⅛ inch to about ½ inch, and/or a ratio of a largest transverse dimension to a length thereof of from about 1:1 to about 0.25:4. 9. The method of claim 1, wherein the supplying liquid step comprises supplying a medicament, wherein the medicament is at least one substance selected from the group consisting of analgesics, anginal preparations, anti-allergics, antibiotics, antihistamines, antitussives, bronchodilators, diuretics, anticholinergics, hormones, and anti-flammatory agents. 10. A method for generating an aerosol, comprising: supplying liquid to a capillary sized flow passage circumferentially surrounded by an insulating cylinder body having an outlet; heating the capillary sized flow passage liquid so as to volatilize at least some of the liquid in the capillary sized flow passage; and directing the volatilized liquid out of the outlet of the capillary sized flow passage into an aerosol confinement sleeve having an inner diameter of about ⅛ inch to about ½ inch located at the outlet of the insulating cylinder body, wherein the aerosol confinement sleeve is located in contact with the insulating cylinder body, and wherein the inner diameter of the aerosol confinement sleeve is the same as the outer diameter of the insulating cylinder body. 11. The method of claim 10, wherein the aerosol confinement sleeve is a small diameter tube. 12. The method of claim 10, wherein the directing the volatilized liquid out of the outlet of the capillary sized flow passage into an aerosol confinement sleeve comprises directing the volatilized liquid out of the outlet of the capillary sized flow passage into the aerosol confinement sleeve with a confined air space having a volume about 0.05 in3 to about 0.4 in3. 13. The method of claim 10, wherein the directing the volatilized liquid out of the outlet of the capillary sized flow passage into an aerosol confinement sleeve comprises directing the volatilized liquid out of the outlet of the capillary sized flow passage into the aerosol confinement sleeve with a length from about ⅛ inch to about 2 inches, a largest transverse dimension from about ⅛ inch to about ½ inch, and/or a ratio of a largest transverse dimension to a length thereof of from about 1:1 to about 0.25:4. 14. The method of claim 10, wherein the supplying liquid step comprises supplying a medicament, wherein the medicament is at least one substance selected from the group consisting of analgesics, anginal preparations, anti-allergics, antibiotics, antihistamines, antitussives, bronchodilators, diuretics, anticholinergics, hormones, and anti-flammatory agents. 15. A method for generating an aerosol, comprising: supplying liquid to a capillary sized flow passage; heating the capillary sized flow passage so as to volatilize at least some of the liquid in the capillary sized flow passage; and directing the volatilized liquid into a confined air space enclosed within an aerosol confinement sleeve, wherein during the directing the volatilized liquid into the confined air space, air is prevented from flowing into the confined air space except at an outlet of the confinement sleeve. 16. The method of claim 15, wherein the directing the volatilized liquid into a confined air space comprises directing the volatilized liquid directly from the capillary sized flow passage into the aerosol confinement sleeve. 17. The method of claim 15, wherein the aerosol confinement sleeve comprises a hollow cylinder, and wherein the supplying liquid step comprises supplying a medicament, wherein the medicament is at least one substance selected from the group consisting of analgesics, anginal preparations, anti-allergics, antibiotics, antihistamines, antitussives, bronchodilators, diuretics, anticholinergics, hormones, and anti-flammatory agents. 18. A method for generating an aerosol, comprising: supplying liquid to a capillary sized flow passage; heating the capillary sized flow passage so as to volatilize at least some of the liquid in the capillary sized flow passage; and directing the volatilized liquid into a confined air space enclosed within an aerosol confinement sleeve, wherein the confined air space has a volume of about 0.05 in3 to about 0.4 in3, wherein during the directing the volatilized liquid into the confined air space, air is prevented from flowing into the confined air space except at an outlet of the confinement sleeve.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (31)
Howell Tony M. ; Sweeney William R., Aerosol and a method and apparatus for generating an aerosol.
Gupta, Rajiv; McRae, Douglas D.; Cox, Kenneth A.; Nichols, Walter A., Aerosol generating devices and methods for generating aerosols having controlled particle sizes.
Schmidt James N.,CAX ; Grychowski Jerry ; Engelbreth Daniel K.,CAX ; Morton Robert,CAX ; Foley Martin P.,CAX, Aerosol medication delivery apparatus and system.
Newell Robert E. (Pinner GB2) Rand Paul K. (Nitchin GB2) Fitzsimmons Robert A. (Barnard Castle GB2), Devices for administering medicaments to patients.
Lloyd Lester J. (Orinda CA) Lloyd Peter M. (Oakland CA) Rubsamen Reid M. (Berkley CA) Schuster Jeffrey A. (Berkley CA), Dynamic particle size control for aerosolized drug delivery.
Collins Alfred L. ; Counts Mary Ellen ; Das Amitabh ; Deevi Seetharama C. ; Fleischhauer Grier S. ; Higgins Charles T. ; Houck ; Jr. Willie G. ; Keen ; Jr. Billy J. ; Lee ; III Robert E. ; Lilly ; Jr, Flavor generating article.
Hindle, Michael; Byron, Peter R.; Gupta, Rajiv, Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution.
Armer Thomas Alex ; Evans Bryce Burwick ; Mohsen Nahed Mohsen ; Pavkov Richard Matthew ; Sudhalkar Atul M., Methods and apparatus for delivering aerosolized medication.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.