Cytokine modulators and related methods of use
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-036/73
A61K-036/45
A61K-036/906
출원번호
UP-0508343
(2006-08-23)
등록번호
US-7758903
(2010-08-09)
발명자
/ 주소
Randolph, Russell K.
Roh-Schmidt, Haeri
출원인 / 주소
Access Business Group International LLC
대리인 / 주소
Brinks Hofer Gilson & Lione
인용정보
피인용 횟수 :
1인용 특허 :
46
초록▼
A composition for modulating cytokines to regulate an inflammatory or immunomodulatory response. The composition can include at least one of rosehips, blueberry, blackberry, elderberry, cranberry, rosemary, clove, feverfew, nettle root, artichoke, reishi mushroom, olive extract, green tea extract, g
A composition for modulating cytokines to regulate an inflammatory or immunomodulatory response. The composition can include at least one of rosehips, blueberry, blackberry, elderberry, cranberry, rosemary, clove, feverfew, nettle root, artichoke, reishi mushroom, olive extract, green tea extract, grape seed extract, resveratrol, viniferin, Aframomum melegueta, boswellia serrata extract, boswellia forte, ipriflavone, tocotrienols, evening primrose oil, INM-176, borage oil, krill oil, at least one type of xanthophyll (e.g., astaxanthin), green coffee extract and ferulic acid. Specifically, a composition of the invention can include: rosehips and at least one of blackberry, blueberry, elderberry, and optionally krill oil; or rosehips, resveratrol and at least one of Aframomum melegueta and astaxanthin. Based on the cytokine modulation and cytokine response inhibition of the composition, it can be used to regulate an immunomodulatory and/or inflammatory response, and subsequently treat diseases and/or abnormal conditions associated with inflammatory response, for example, cardiovascular conditions, arthritis, osteoporosis and Alzheimer's disease.
대표청구항▼
The invention claimed is: 1. A dietary supplement for modulating an immune response in a subject comprising rosehips, at least one of resveratrol and viniferin, and a blueberry ingredient, to provide a daily dosage of about 300-1500 mg rosehips, about 41-500 mg blueberry ingredient, and about 10-15
The invention claimed is: 1. A dietary supplement for modulating an immune response in a subject comprising rosehips, at least one of resveratrol and viniferin, and a blueberry ingredient, to provide a daily dosage of about 300-1500 mg rosehips, about 41-500 mg blueberry ingredient, and about 10-150 mg resveratrol or viniferin wherein the dietary supplement is effective for reducing the expression of an inflammatory cytokine. 2. The dietary supplement of claim 1, wherein the inflammatory cytokine is interleukin-1. 3. The dietary supplement of claim 1, further comprising a blackberry ingredient. 4. The dietary supplement of claim 1, further comprising at least one of Aframomum melegueta extract and a blackberry ingredient. 5. The dietary supplement of claim 1, wherein the subject possesses an interleukin-1 (IL-1) pattern 1 genotype. 6. The dietary supplement of claim 1, wherein a single dosage unit of the dietary supplement comprises about 300-1500 mg of rosehips, about 41-500 mg of blueberry ingredient, and about 10-150 mg of resveratrol or viniferin. 7. The dietary supplement of claim 4, wherein the dietary supplement further provides a daily dosage of about 50-300 mg of blackberry ingredient and about 75-500 mg of Aframomum melegueta extract.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (46)
Goodman David William,CAX, Administration of resveratrol to prevent or treat restenosis following coronary intervention.
Theresa Callaghan NL; Thierry Oddos FR; Gerard Gendimenico ; Katharine Martin, Method for the topical treatment and prevention of inflammatory disorders and related conditions using extracts of feverfew (Tanacetum parthenium).
Pero Ronald W.,SEX, Method of preparation and composition of a water soluble extract of the plant species Uncaria for enhancing immune, anti-inflammatory and anti-tumor processes of warm blooded animals.
Hewitt Charles W. (698 Tranquility Turn Marlton NJ 08053) Black Kirby S. (13401 Sussex Pl. Santa Ana CA 92705), Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants.
John M. Pezzuto ; Richard C. Moon ; Mei-Shiang Jang ; Aomar Ouali CA; Shengzhao Lin CA; Karla Slowing Barillas ES, Pharmaceutical formulations of resveratrol and methods of use thereof.
Beuscher Norbert (Salzgitter DEX) Willigmann Ingo (Goslar DEX), Pharmaceutically active composition extracted from tanacetum parthenium, process for its extraction, and pharmaceutical.
Wu Wencai (11 Ganggou ; Haidian District Beijing 100080 CNX), Preparation of herbal medicines by using a multi-enzyme system, herbal medicines prepared and their uses.
Kreuter Mathias-Heinrich,CHX ; Steiner Rudolf,CHX, Process for the removal of undesired lipophilic contaminations and/or residues, which are contained in beverages or in vegetable preparations.
Kharazmi Arsalan,DKX ; Winther Kaj,DKX ; Rein Eydbj.o slashed.rg,DKX, Rose-hip formulations as anti-inflammatory natural medicine for alleviating/reducing symptoms associated with inflammation and arthritis.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.