A dry type adhesive device for teeth whitening in which a peroxide tooth whitening agent is stabilized is disclosed. The dry type adhesive device for tooth whitening comprises a matrix type adhesive layer and a backing layer wherein the adhesive layer contains a peroxide as a teeth whitening agent a
A dry type adhesive device for teeth whitening in which a peroxide tooth whitening agent is stabilized is disclosed. The dry type adhesive device for tooth whitening comprises a matrix type adhesive layer and a backing layer wherein the adhesive layer contains a peroxide as a teeth whitening agent and a hydrophilic glassy polymer as a base polymer so that the hydrophilic glassy polymer provides strong adhesion to teeth when hydrated at the enamel layer of the teeth in the moist oral cavity and the whitening agent is released. In particular, although the dry type adhesive device is touched with the hands or contact the skin during attaching to the teeth prior to hydration, no stickiness and releasing of the whitening agent takes place, thus being safe. In addition, since the dry type patch has strong adhesive strength to the teeth and excellent adhesion maintenance after being hydrated and attached to the teeth, it can remain attached to the teeth for a long time and thus exhibits excellent whitening effect even low concentrations of a whitening agent. Furthermore, the dry type adhesive device can provide excellent whitening within a short period of time.
대표청구항▼
What is claimed is: 1. A method for teeth whitening comprising: providing a dry adhesive device for tooth attachment comprising a matrix adhesive layer and a backing layer, wherein the adhesive layer contains a peroxide teeth whitening agent and a hydrophilic glassy polymer as a base polymer select
What is claimed is: 1. A method for teeth whitening comprising: providing a dry adhesive device for tooth attachment comprising a matrix adhesive layer and a backing layer, wherein the adhesive layer contains a peroxide teeth whitening agent and a hydrophilic glassy polymer as a base polymer selected from polyalkylvinyl ether-maleic acid copolymer, polyvinyl alcohol, polyacrylic acid, poloxamer 407, polyvinyl pyrrolidone-vinyl acetate copolymer, polyvinyl pyrrolidone (PVP), polyquaternium-11, polyquaternium-39, carbomer, hydroxypropylmethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, gelatin and sodium alginate; hydrating the adhesive layer; increasing the adhesive strength of said adhesive layer as compared to its dry state prior to its hydration; releasing the tooth whitening agent on the enamel layers of the teeth when the adhesive layer is being hydrated; maintaining the adhesive strength of the device substantially constant while the teeth whitening agent is being released from the adhesive layer; and contacting the adhesive layer with teeth for a period of about 15 minutes, wherein said hydrophilic glassy polymer is present in amount sufficient to increase the adhesive strength by at least 62% to 260% post hydration. 2. The method according to claim 1, wherein the period of contacting is about 30 minutes. 3. The method according to claim 1, wherein the period of contacting is about 60 minutes. 4. The method according to claim 1, wherein the period of contacting is about 90 minutes. 5. The method according to claim 1, wherein the polymer used in the backing layer comprises a polymer selected from the group consisting of polyvinyl acetate, ethyl cellulose, polymethyl methacrylate, methacryloylethyl betain/methacrylate copolymer, methacrylic acid copolymer, aminoalkylmethacrylate copolymer, cellulose acetate phthalate, shellac or a mixture thereof. 6. The method according to claim 1, wherein the peroxide is used together with a peroxide stabilizer. 7. The method according to claim 1, wherein the peroxide stabilizer is one or more compounds selected from the group consisting of alkylaryl sulphonates, alkyl sulphonates, alkyl carboxylates, alkyldiphenyloxide disulphonates, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan monooleate, sorbitan trioleate and polyoxyethelene sorbitan fatty acid esters. 8. The method according to claim 1, further comprising a polyphosphate for whitening effect enhancement. 9. The method according to claim 8, wherein the polyphosphate is at least one compound selected from tetrasodium pyrophosphate, sodium acid pyrophosphate, sodium hexametaphosphate, sodium tripolyphosphate, sodium potassium tripolyphosphate, tetrapotassium pyrophosphate and acidic sodium metapolyphosphate. 10. The method according to claim 1, wherein the adhesive layer thickness is about 100 μm and the peroxide concentration in the adhesive layer is between 1-4% by weight. 11. The method according to claim 1, wherein the adhesive layer thickness is about 150 μm and the peroxide concentration in the adhesive layer is between 1-4% by weight. 12. The method according to claim 1, wherein the adhesive layer thickness is about 200 μm and the peroxide concentration in the adhesive layer is between 1-4% by weight. 13. The method according to claim 1, wherein the adhesive layer thickness is about 60 μm and the peroxide concentration in the adhesive layer is between 4-7.5% by weight. 14. The method according to claim 1, wherein the adhesive layer thickness is about 80 μm and the peroxide concentration in the adhesive layer is between 4-7.5% by weight. 15. The method according to claim 1, wherein the adhesive layer thickness is about 40 μm and the peroxide concentration in the adhesive layer is greater than 7.5% by weight. 16. The method according to claim 1, wherein the adhesive layer thickness is about 50 μm and the peroxide concentration in the adhesive layer is greater than 7.5% by weight. 17. A method for teeth whitening comprising: providing a dry adhesive device for tooth attachment comprising a matrix adhesive layer and a backing layer, wherein the adhesive layer contains a peroxide teeth whitening agent and a hydrophilic glassy polymer as a base polymer comprising PVP; hydrating the adhesive layer; increasing the adhesive strength of said adhesive layer as compared to its dry state prior to its hydration; releasing the tooth whitening agent on the enamel layers of the teeth when the adhesive layer is being hydrated; maintaining the adhesive strength of the device substantially constant while the teeth whitening agent is being released from the adhesive layer; and contacting the adhesive layer with teeth for a period of about 15 minutes, wherein said hydrophilic glassy polymer is present in an amount sufficient to increase the adhesive strength by at least 62% to 260% post hydration. 18. The method according to claim 17, wherein the period of contacting is about 30 minutes. 19. The method according to claim 17, wherein the period of contacting is about 60 minutes. 20. The method according to claim 17, wherein the period of contacting is about 90 minutes. 21. The method according to claim 17, wherein the backing layer comprises a polymer selected from the group consisting of polyvinyl acetate, ethyl cellulose, polymethyl methacrylate, methacryloylethyl betain/methacrylate copolymer, methacrylic acid copolymer, aminoalkylmethacrylate copolymer, cellulose acetate phthalate, shellac or a mixture thereof. 22. The method according to claim 17, wherein the peroxide is used together with a peroxide stabilizer. 23. The method according to claim 22, wherein the peroxide stabilizer is one or more compounds selected from the group consisting of alkylaryl sulphonates, alkyl sulphonates, alkyl carboxylates, alkyldiphenyloxide disulphonates, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan monooleate, sorbitan trioleate and polyoxyethylene sorbitan fatty acid esters. 24. The method according to claim 17, further comprising a polyphosphate for whitening effect enhancement. 25. The method according to claim 24, wherein the polyphosphate is at least one compound selected from tetrasodium pyrophosphate, sodium acid pyrophosphate, sodium hexametaphosphate, sodium tripolyphosphate, sodium potassium tripolyphosphate, tetrapotassium pyrophosphate and acidic sodium metapolyphosphate. 26. The method according to claim 17, wherein the adhesive layer thickness is about 100 μm and the peroxide concentration in the adhesive layer is between 1-4% by weight. 27. The method according to claim 17, wherein the adhesive layer thickness is about 150 μm and the peroxide concentration in the adhesive layer is between 1-4% by weight. 28. The method according to claim 17, wherein the adhesive layer thickness is about 200 μm and the peroxide concentration in the adhesive layer is between 1-4% by weight. 29. The method according to claim 18, wherein the adhesive layer thickness is about 60 μm and the peroxide concentration in the adhesive layer is between 4-7.5% by weight. 30. The method according to claim 17, wherein the adhesive layer thickness is about 80 μm and the peroxide concentration in the adhesive layer is between 4-7.5% by weight. 31. The method according to claim 17, wherein the adhesive layer thickness is about 40 μm and the peroxide concentration in the adhesive layer is greater than 7.5% by weight. 32. The method according to claim 17, wherein the adhesive layer thickness is about 50 μm and the peroxide concentration in the adhesive layer is greater than 7.5% by weight. 33. The method according to claim 1, wherein the hydrophilic glassy polymer comprise PVP or sodium alginate. 34. The method according to claim 33, wherein the PVP has a molecular weight of greater than 500,000. 35. The method according to claim 33, wherein the peroxide is hydrogen peroxide. 36. The method according to claim 35, further comprising sodium acid pyrophosphate.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (206)
Prencipe Michael (East Windsor NJ) Drago Vincent (Staten Island NY), Abrasive tooth whitening dentifrice of improved stability.
Schiraldi Michael T. (East Brunswick NJ) Perl Martin M. (Brooklyn NY) Rubin Howard (Rockaway NJ), Bioadhesive extruded film for intra-oral drug delivery and process.
Schiraldi Michael T. (East Brunswick NJ) Perl Martin M. (Brooklyn NY) Rubin Howard (Rockaway NJ), Bioadhesive extruded film for intra-oral drug delivery and process.
Sagel Paul A. ; Dirksing Robert S. ; Rohman Frederick J., Delivery system for a tooth whitener using a strip of material having low flexural stiffness.
Sagel Paul Albert ; Dirksing Robert Stanley ; Rohman Frederick James, Delivery system for a tooth whitener using a strip of material having low flexural stiffness.
Dirksing Robert S. ; Sagel Paul A. ; Tweddell ; III Richard, Delivery system for an oral care substance using a permanently deformable strip of material.
Sagel Paul A. ; Dirksing Robert S. ; Rohman Frederick J., Delivery system for an oral care substance using a strip of material having low flexural stiffness.
Sagel Paul Albert ; Dirksing Robert Stanley ; Rohman Frederick James, Delivery system for an oral care substance using a strip of material having low flexural stiffness.
Sagel Paul Albert ; Dirksing Robert Stanley ; Rohman Frederick James ; Majeti Satyanarayana ; Reno Elizabeth Ann, Delivery system for an oral care substance using a strip of material having low flexural stiffness.
Haynie Michel B. (1259 E. 8320 South Sandy UT 84094), Dental bleach system having separately compartmented fumed silica and hydrogen peroxide and method of using.
Curtis John (Bloomsbury NJ) Nahoo Salim (Piscataway NJ) Prencipe Michael (E. Windsor NJ), Dental material and method for applying preventative and therapeutic agents.
Curtis John (Bloomsbury NJ) Nathoo Salim (Piscataway NJ) Prencipe Michael (East Windsor NJ), Dental material and method for applying preventative and therapeutic agents.
Santalucia John (New Brunswick NJ) Crawford Richard J. (Asbury NJ) Viscio David B. (Monmouth Junction NJ) Dixit Nagaraj S. (Plainsboro NJ) Collins Michael A. (Hazlet NJ), Dentifrice compositions containing reactive ingredients stabilized with alkali metal compounds.
Santalucia John (New Brunswick NJ) Crawford Richard J. (Asbury NJ) Viscio David B. (Monmouth Junction NJ) Dixit Nagaraj S. (Plainsboro NJ) Collins Michael A. (Hazlet NJ), Dentifrice compositions containing reactive ingredients stabilized with alkali metal compounds.
Staples Lorna C. (Teaneck) Spanier Henry C. (West Milford) Scaglione Felice (Hasbrouck Heights) Karwowski Jan (Franklin Lakes NJ), Devices, compositions and the like having or containing an inorganic pyrophosphate.
Ebert Charles D. (Salt Lake City UT) Venkateshwaran Srinivasan (Salt Lake City UT) Heiber Werner (Salt Lake City UT) Borsadia Suresh (Salt Lake City UT), Drug-containing adhesive composite transdermal delivery device.
Prencipe Michael ; Drago Vincent O. ; Wong Mike ; Self Barry D. ; Williams Malcolm ; Afflitto John, Dual component antiplaque and tooth whitening composition.
Prencipe Michael ; Wong Mike ; Drago Vincent O. ; Bentley Marcus ; Hassan Mahmoud ; Dixit Nagaraj S., Dual component antiplaque and tooth whitening composition.
Ravi Subramanyam ; Malcolm Williams ; Petros Gebreselassie ; Xiaoyan Liu ; Angelo Zaccagnino ; James G. Masters, Dual component dentifrice for reducing mouth odors.
Masters James G. ; Gambogi Robert J. ; Wong Mike ; Hoic Diego A. ; Drago Vincent O., Dual component oral composition having accelerated tooth whitening effect.
Togo Ichiro (Himeji JPX) Hatazawa Yasuyoshi (Himeji JPX), Magnetic sensor with bobbin, sleeve and terminal bed for detecting a change in magnetic flux.
Kim Jung J. (Anyang-shi KRX) Lee Woo Y. (Anyang-shi KRX) Ahn Jong W. (Seoul KRX) Han Sang H. (Suwon-shi KRX), Medicinal adhesive for percutaneous administration.
van den Bosch Willem Frederik,NLX, Method for preparing a preparation for bleaching teeth or for treating skin complaints and mucous membrane disorders.
Merianos John J. (Middletown NJ) Lieberman Herbert A. (Livingston NJ) Login Robert B. (Oakland NJ), Method for reducing the microbial content of surfaces with a microbiocidal, anhydrous complex of PVP-H2O상세보기
Diasti, Adam; Philp, Jr., Graham K.; Brown, Damon J., Method for whitening teeth.
Burgess Steven Carl ; Sheets Connie Lynn ; Bernheim Sue Ellen ; Berta James Albert ; Britt Michael Lashawn, Method of making a tartar control dentifrice containing fluoride and peroxide.
Anthony Cerami ; Peter C. Ulrich ; Dilip R. Wagle ; San-Bao Hwang ; Sara Vasan ; John J. Egan, Method of treating certain indications associated with hyperglycemia.
Kizawa Hidenori (Tokyo JPX) Fujiyama Norimasa (Tokyo JPX) Kobayashi Jitsuo (Kanagawa JPX) Ito Akinori (Niigata JPX), Mucous membrane-adhering film preparation and process for its preparation.
Englebert Stephen M. (Woodstock GA) Wagner Ann L. (Hortonville WI) Hafer Gregory S. (Atlanta GA) Logsdon Nanette J. (Appleton WI), Nonwoven web with projections.
Jonathan James Witt ; Rohan Lalith Wimalasena ; Andrew Lee Wong ; Eric Altman Goulbourne, Jr. ; Matthew Joseph Doyle, Oral care compositions comprising chlorite and methods.
Rajaiah, Jayanth; Ernst, Lisa Catron; Case, Ann Maria; Ha, Thinh Nguyen; Glandorf, William Michael; Mayer, Christopher Robert, Oral care kits and compositions.
Manmohan Bhakoo GB; Andrew Joiner GB; Karen Anne Steele GB; David Taylor GB; Katherine Mary Thompson GB; David William Thornthwaite GB, Oral composition.
Church John A. (Princeton Junction NJ) Prencipe Michael (East Windsor NJ) Lewin Menachem (Jerusalem ILX), Oral composition having improved tooth whitening effect.
Burgess Steven Carl ; Sheets Connie Lynn ; Bernheim Sue Ellen ; Berta James Albert ; Britt Michael Lashawn, Oral compositions containing fluoride, pyrophosphate, peroxide, and nonionic and/or amphoteric surfactants.
Vines Douglass M. (Farminton Hills MI) Vogler Gerald L. (Maplewood MN) Williams Richard C. (River Falls WI) Cheesebrow Thomas G. (Vadnais Heights MN), Paint masking assembly and method of masking.
Lerner E. Itzhak,ILX ; Rosenberger Vered,ILX ; Flashner Moshe,ILX, Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity.
Merianos John J. (Middletown NJ) Login Robert P. (Oakland NJ) Garelick Paul (South Plainfield NJ), Stabilized, aqueous, film-forming antimicrobial compositions of hydrogen peroxide.
Rajaiah, Jayanth; Ernst, Lisa Catron; Case, Ann Maria; Ha, Thinh Nguyen; Glandorf, William Michael; Mayer, Christopher Robert, Systems for delivering a cosmetic and/or therapeutic active to oral surfaces using an integral carrier.
Jan A. Orlowski ; David V. Butler, Two-part composition for high efficacy teeth whitening comprising a mixture of peroxides and/or percarbonates of metals.
Gaglio Thomas J. (4421 La Paloma Santa Barbara CA 93105) Santoriello Luigi (3463 State St. ; #359 Santa Barbara CA 93105), Viscous fluid dispensing apparatus.
Biegajski James E. (Foster City CA) Venkatraman Subbu S. (Palo Alto CA) Scott Ann M. (Mountain View CA), Water-soluble pressure-sensitive mucoadhesive and devices provided therewith for emplacement in a mucosa-lined body cavi.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.