초록 ▼

A co-injection process is provided for fabricating improved multi-layer containers, including but not limited to blood collection tubes, evacuated blood collection tubes, culture bottles, centrifuges tubes, and syringe barrels. The container includes a tube (10) having a bottom wall (12) and a side

A co-injection process is provided for fabricating improved multi-layer containers, including but not limited to blood collection tubes, evacuated blood collection tubes, culture bottles, centrifuges tubes, and syringe barrels. The container includes a tube (10) having a bottom wall (12) and a side wall (14) with an open end (18). The container can be provided with a stopper having an upper portion (22) and a skirt with an outside portion (30), a well (34) and a cavity (36). The tube and stopper assembly can be used for medical purposes including containing a blood sample within an enclosed interior space (40).

대표청구항 ▼

What is claimed is: 1. A process for fabricating a container having a bottom wall, a top edge, and a sidewall between the bottom wall and top edge, comprising the steps of: providing a first molten polymeric material and a second molten polymeric material, the first and second polymeric materials b

What is claimed is: 1. A process for fabricating a container having a bottom wall, a top edge, and a sidewall between the bottom wall and top edge, comprising the steps of: providing a first molten polymeric material and a second molten polymeric material, the first and second polymeric materials being non-compatible; and directing the first and second molten polymeric materials through a nozzle section, a cold sprue and into a mold cavity that comprises a region for integrally forming the bottom wall of the container, wherein the first and second molten polymeric materials co-flow in the mold cavity for at least a portion of the fabrication process, wherein, during the co-flow, the nozzle section directs the first and second molten polymeric materials into the mold cavity as inner and outer skin layers of the first molten polymeric material with a core layer of the second molten polymeric material between the inner and outer skin layers, removing the solidified first and second polymeric materials from within the cold sprue. 2. The process of claim 1, wherein the inner and outer skin layers are directly adjacent the core layer. 3. The process of claim 1, wherein the first and second polymeric materials are selected from the group consisting of ethylene vinyl alcohol copolymer, polyester, copolymers of ethylene vinyl alcohol copolymer and polyester, cyclic olefin copolymers, and polypropylene. 4. The process of claim 3, wherein the first and second polymeric materials are, respectively, polypropylene and ethylene vinyl alcohol copolymer, or cyclic olefin copolymer and ethylene vinyl alcohol copolymer, or polypropylene and polyester, or cyclic olefin copolymer and polyester. 5. The process of claim 4, wherein the first and second polymeric materials are, respectively, polypropylene and ethylene vinyl alcohol copolymer. 6. The process of claim 1, wherein the first polymeric material is a gas barrier material and the second polymeric material is a liquid vapor barrier material, or the first polymeric material is a liquid vapor barrier material and the second polymeric material is a gas barrier material. 7. The process of claim 1, wherein the core layer is encapsulated by the skin layers. 8. The process of claim 1, wherein the core layer exhibits substantially continuous coverage throughout the bottom wall and throughout the side wall. 9. The process of claim 1, wherein the core layer exhibits substantially continuous coverage throughout the bottom wall and in the side wall up to a region of the container that is intended to be contacted by a stopper. 10. A process for fabricating a container having a bottom wall, a top edge, and a sidewall between the bottom wall and top edge, comprising the steps of: providing a first molten polymeric material and a second molten polymeric material; and directing the first and second molten polymeric materials through a nozzle section into a mold cavity that comprises a region for integrally forming the bottom wall of the container, wherein the first and second molten polymeric materials co-flow in the mold cavity for at least a portion of the fabrication process, wherein, during the co-flow, the nozzle section directs the first and second molten polymeric materials into the mold cavity as annular inner and outer skin layers of the first molten polymeric material with an annular core layer of the second molten polymeric material between the inner and outer skin layers, and wherein a cold sprue is located between the nozzle section and the mold cavity, such that the polymeric materials pass through the cold sprue before flowing into the mold cavity and the polymeric materials are removed from the cold sprue after the co-flow portion of the fabrication process. 11. A process for fabricating a container having a bottom wall, a top edge, and a sidewall between the bottom wall and top edge, comprising the steps of: providing a first molten polymeric material, a second molten polymeric material, and a third molten polymeric material, the first and second polymeric materials being non-compatible, and the second and third polymeric materials being non-compatible; and directing the first and second and third molten polymeric materials through a nozzle section, a cold sprue and into a mold cavity that comprises a region for integrally forming the bottom wall of the container, wherein the first and second and third molten polymeric materials co-flow in the mold cavity for at least a portion of the fabrication process, wherein, during the co-flow, the nozzle section directs the first and second and third molten polymeric materials into the mold cavity as, respectively, an inner skin layer, a core layer, and an outer skin layer, with the core layer located between the inner and outer skin layers degating the cold sprue from the container or the mold cavity. 12. The process of claim 11, wherein the inner and outer skin layers are directly adjacent the core layer. 13. The process of claim 11, wherein the first, second, and third molten polymeric materials are identical or different, and one or more of the polymeric materials comprise one or more additives selected from the group consisting of organic or inorganic fillers, dyes, plasticizers, slip agents, processing aids, stabilizers, ultraviolet light barriers, molecular scavenger materials, radiation barrier materials, chargeable dyes, materials that react to temperature or pressure changes, and structural additives. 14. The process of claim 11, wherein the first and second and third polymeric materials are identical or different, and are selected from the group consisting of ethylene vinyl alcohol copolymer, polyester, copolymers of ethylene vinyl alcohol copolymer and polyester, cyclic olefin copolymers, and polypropylene. 15. The process of claim 11, wherein the first and second and third polymeric materials include at least one gas barrier material and at least one liquid vapor barrier material. 16. The process of claim 11, wherein the core layer is encapsulated by the skin layers. 17. The process of claim 11, wherein one or more of the first, second, and third polymeric materials comprise a nanocomposite material. 18. The process of claim 1, wherein a substantially continuous annular core layer is formed in the container. 19. The process of claim 1, wherein only the first molten polymeric material flows in the mold cavity for the initial portion of the fabrication process. 20. The process of claim 10, wherein only the first molten polymeric material flows in the mold cavity for the initial portion of the fabrication process.