Marked precoated medical device and method of manufacturing same
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
C08J-007/18
A61L-033/00
B05D-003/00
출원번호
UP-0402218
(2009-03-11)
등록번호
US-7811623
(2010-11-01)
발명자
/ 주소
Nesbitt, Bruce
출원인 / 주소
Innovatech, LLC
대리인 / 주소
K&L Gates LLP
인용정보
피인용 횟수 :
8인용 특허 :
185
초록▼
A method of manufacturing a coated medical device, includes applying a first low-friction coating to a surface of the medical device. The first low-friction coating includes a first colored pigment, such as a relatively light colored pigment. After applying the first low-friction coating, a suitable
A method of manufacturing a coated medical device, includes applying a first low-friction coating to a surface of the medical device. The first low-friction coating includes a first colored pigment, such as a relatively light colored pigment. After applying the first low-friction coating, a suitable laser and laser energy is selectively applied to different areas of the coated medical device. The laser ablates or removes the first low-friction coating (at the different areas of the medical device) to leave the bare metal substrate of the medical device exposed. After selectively removing one or more portions of the first low-friction coating, a second low-friction coating is applied to the exposed bare metal substrate of the medical device and suitably cured. The second low-friction coating includes a second colored pigment, such as a relatively dark colored pigment, wherein the second colored pigment contrasts the first colored pigment of the first low-friction coating.
대표청구항▼
The invention is claimed as follows: 1. A method of manufacturing a coated medical device including a metal substrate, said method comprising: (a) applying a first coating to a section of an outer surface of the metal substrate of the medical device, said section configured to contact tissue of a b
The invention is claimed as follows: 1. A method of manufacturing a coated medical device including a metal substrate, said method comprising: (a) applying a first coating to a section of an outer surface of the metal substrate of the medical device, said section configured to contact tissue of a body during a medical procedure, said first coating including: (i) a first binder, (ii) a first pigment of a first color, and (iii) a plurality of particles of a first low-friction material; (b) at least partially curing said first coating; (c) heating a first portion of the first coating applied to the outer surface of the medical device to remove the first portion of the first coating, but not all of the applied first coating, and to expose a first portion of the outer surface of the metal substrate of the medical device under the removed first portion of the first coating; (d) electrophoretically applying a second, different coating to said exposed first portion of the outer surface of the metal substrate of the medical device, said second coating including: (i) a second binder, (ii) a second pigment of a second color, said second color being of a contrasting hue than the first color, and (iii) a plurality of particles of a second low-friction material; and (e) curing said second coating and any uncured first coating. 2. The method of claim 1, which includes heating a second portion of the first coating applied to the outer surface of the medical device to remove the second portion of the first coating and to expose a second portion of the outer surface of the metal substrate of the medical device under the removed second portion of the first coating and electrophoretically applying the second, different coating to said exposed second portion of the outer surface of the metal substrate of the medical device. 3. The method of claim 1, wherein the first low friction material and the second low friction material are a same low friction material. 4. The method of claim 1 wherein heating the first portion of the first coating applied to the outer surface of the medical device includes using an energy source selected from the group consisting of: a radiant heat energy source, an induction heat energy source, a source of hot air, an open flame, at least one electric filament, at least one magnet, and at least one laser. 5. The method of claim 1, wherein heating the first portion of the first coating applied to the outer surface of the medical device and electrophoretically applying the second coating to the exposed first portion of the outer surface of the metal substrate of the medical device forms at least one marking selected from the group consisting of: at least one line parallel to a longitudinal direction of the medical device, at least one line perpendicular to the longitudinal direction of the medical device and at least one line transverse to the longitudinal direction of the medical device. 6. The method of claim 1, wherein the second coating is a high-water content electrophoretic paint emulsion. 7. The method of claim 6, wherein electrophoretically applying the second coating to said exposed first portion of the outer surface of the metal substrate of the medical device includes immersing at least part of the medical device in the high water content electrophoretic paint emulsion and passing an electric current through both the medical device and the paint emulsion. 8. The method of claim 1, wherein the first coating and the second coating each include a plurality of interspersed anti-microbial particles. 9. The method of claim 8, wherein the anti-microbial particles are selected from the group consisting of: silver particles, glass-silver particles, silver-ceramic particles, and ceramic particles. 10. The method of claim 1, wherein the medical device is a medical guide wire. 11. The method of claim 1, wherein the medical device is selected from the group consisting of: a medical wire, a catheter, a needle, a biopsy device, a cannula, an electrosurgical electrode, a soft tissue needle, a soft tissue tubular device, a probe, and a blade. 12. The method of claim 1, which includes applying an additional top coating to the first section of the medical device, said additional top coating including a plurality of particles of a low-friction material. 13. The method of claim 1, wherein the first pigment is selected from a group consisting of: a phthalocyanine blue, a phthalocyanine green, a diarylide yellow, a diarylide orange, a quanacridone, a naphthol, a toluidine red, a carbizole violet, a carbon black, an iron oxide red, an iron oxide yellow, a chrome oxide green, a titanium oxide white, a cadmium red, a ultramarine blue, a moly orange, a lead chromate yellow, a mixed metal oxide, a talc, a calcium carbonate, a silicate and sulfate, a silica, a mica, an aluminum hydrate and silicate, a barium suflate, a pearl pigment, a kaolin, an aluminum silicate derivative, an antimony trioxide, a metallic pigment, an aluminum flake pigment, and an iron oxide. 14. The method of claim 1, wherein the second pigment is selected from a group consisting of: a phthalocyanine blue, a phthalocyanine green, a diarylide yellow, a diarylide orange, a quanacridone, a naphthol, a toluidine red, a carbizole violet, a carbon black, an iron oxide red, an iron oxide yellow, a chrome oxide green, a titanium oxide white, a cadmium red, a ultramarine blue, a moly orange, a lead chromate yellow, a mixed metal oxide, a talc, a calcium carbonate, a silicate and sulfate, a silica, a mica, an aluminum hydrate and silicate, a barium sulfate, a pearl pigment, a kaolin, an aluminum silicate derivative, an antimony trioxide, a metallic pigment, an aluminum flake pigment, and an iron oxide. 15. A method of manufacturing a coated medical device including a metal substrate, said method comprising: (a) applying a first coating to a section of an outer surface of the metal substrate of the medical device, said section configured to contact tissue of a body during a medical procedure, said first coating including: (i) a first binder, (ii) a first pigment of a first color, and (iii) a plurality of particles of a first low-friction material; (b) at least partially curing said first coating; (c) for each of a plurality of spaced apart portions of the first coating applied to the outer surface of the medical device, heating said portion of the first coating to remove said portion of the first coating, but not all of the applied first coating, and to expose a portion of the outer surface of the metal substrate of the medical device under the removed portion of the first coating; (d) electrophoretically applying a second, different coating to each of said exposed portions of the outer surface of the metal substrate of the medical device, said second coating including: (i) a second binder, (ii) a second pigment of a second color, said second color being of a contrasting hue than the first color, and (iii) a plurality of particles of a second low-friction material; and (e) curing said second coating and any uncured first coating. 16. The method of claim 15, wherein the first low friction material and the second low friction material are a same low friction material. 17. The method of claim 15, wherein heating the portions of the first coating applied to the outer surface of the medical device and electrophoretically applying the second coating to the exposed portions of the outer surface of the metal substrate of the medical device forms at least one marking selected from the group consisting of: at least one line parallel to a longitudinal direction of the medical device, at least one line perpendicular to the longitudinal direction of the medical device and at least one line transverse to the longitudinal direction of the medical device. 18. The method of claim 15, wherein the second coating is a high-water content electrophoretic paint emulsion. 19. The method of claim 18, wherein electrophoretically applying the second coating to each of said exposed portions of the outer surface of the metal substrate of the medical device includes immersing at least part of the medical device in the high water content electrophoretic paint emulsion and passing an electric current through both the medical device and the paint emulsion. 20. The method of claim 15, wherein the first coating and the second coating each include a plurality of interspersed anti-microbial particles. 21. The method of claim 20, wherein the anti-microbial particles are selected from the group consisting of: silver particles, glass-silver particles, silver-ceramic particles, and ceramic particles. 22. The method of claim 15, wherein the medical device is a medical guide wire. 23. The method of claim 15, wherein the medical device is selected from the group consisting of: a medical wire, a catheter, a needle, a biopsy device, a cannula, an electrosurgical electrode, a soft tissue needle, a soft tissue tubular device, a probe, and a blade. 24. The method of claim 15, which includes applying an additional top coating to the first section of the medical device, said additional top coating including a plurality of particles of a low-friction material. 25. A method of manufacturing a coated medical device including a metal substrate, said method comprising: (a) heating a first portion of a first coating applied to a section of an outer surface of the medical device to remove the first portion of the first coating, but not all of the applied first coating and to expose a first portion of the outer coating of the metal substrate of the medical device under the removed first portion of the first coating, said first coating including a first binder, a first pigment of a first color, and a plurality of particles of a first low-friction material, said section configured to contact tissue of a body during a medical procedure; (b) electrophoretically applying a second, different coating to said exposed first portion of the outer surface of the metal substrate of the medical device, said second coating including a second binder, a second pigment of a second color, said second color being of a contrasting hue than the first color, and a plurality of particles of a second low-friction material; and (c) curing said second coating and any uncured first coating. 26. The method of claim 25, which includes heating a second portion of the first coating applied to the outer surface of the medical device to remove the second portion of the first coating and to expose a second portion of the outer coating of the metal substrate of the medical device under the removed second portion of the first coating, and electrophoretically applying the second, different coating to said exposed second portion of the outer surface of the metal substrate of the medical device. 27. The method of claim 25, which includes heating a plurality of spaced-apart portions of the first coating on the outer surface of the medical device to remove the plurality of spaced-apart portions of the first coating and to expose a plurality of portions of the outer coating of the metal substrate of the medical device under the removed spaced-apart portions of the first coating and electrophoretically applying the second, different coating to each of the exposed space-apart portions of the outer surface of the metal substrate of the medical device. 28. The method of claim 25, wherein the first low friction material and the second low friction material are a same low friction material. 29. The method of claim 25, wherein the first coating applied to the outer surface of the medical device is partially cured prior to heating the first portion of the first coating. 30. The method of claim 25, wherein the first coating applied to the outer surface of the medical device is fully cured prior to heating the first portion of the first coating. 31. The method of claim 25, wherein heating the first portion of the first coating applied to the first portion of the outer surface of the medical device includes using an energy source selected from the group consisting of: a radiant heat energy source, an induction heat energy source, a source of hot air, an open flame, at least one electric filament, at least one magnet, and at least one laser. 32. The method of claim 25, wherein heating the first portion of the first coating applied to the outer surface of the medical device and electrophoretically applying the second coating to the exposed portions of the outer surface of the metal substrate of the medical device forms at least one marking selected from the group consisting of: at least one line parallel to a longitudinal direction of the medical device, at least one line perpendicular to the longitudinal direction of the medical device and at least one line transverse to the longitudinal direction of the medical device substantially transverse to the longitudinal direction of the medical device. 33. The method of claim 25, wherein the second coating is a high-water content electrophoretic paint emulsion. 34. The method of claim 33, wherein electrophoretically applying the second coating to said first portion of the exposed outer surface of the metal substrate of the medical device includes immersing at least part of the medical device in the high water content electrophoretic paint emulsion and passing an electric current through both the medical device and the paint emulsion. 35. The method of claim 25, wherein the first coating and the second coating each include a plurality of interspersed anti-microbial particles. 36. The method of claim 35, wherein the anti-microbial particles are selected from the group consisting of: silver particles, glass-silver particles, silver-ceramic particles, and ceramic particles. 37. The method of claim 25, wherein the medical device is a medical guide wire. 38. The method of claim 25, wherein the medical device is selected from the group consisting of: a medical wire, a catheter, a needle, a biopsy device, a cannula, an electrosurgical electrode, a soft tissue needle, a soft tissue tubular device, a probe, and a blade. 39. The method of claim 25, which includes applying an additional top coating to a first section of the medical device, said additional top coating including a plurality of particles of a low-friction material. 40. The method of claim 25, wherein the second pigment is selected from a group consisting of: a phthalocyanine blue, a phthalocyanine green, a diarylide yellow, a diarylide orange, a quanacridone, a naphthol, a toluidine red, a carbizole violet, a carbon black, an iron oxide red, an iron oxide yellow, a chrome oxide green, a titanium oxide white, a cadmium red, a ultramarine blue, a moly orange, a lead chromate yellow, a mixed metal oxide, a talc, a calcium carbonate, a silicate and sulfate, a silica, a mica, an aluminum hydrate and silicate, a barium sulfate, a pearl pigment, a kaolin, an aluminum silicate derivative, an antimony trioxide, a metallic pigment, an aluminum flake pigment, and an iron oxide.
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