Devices for maintaining patency of surgically created channels in tissue
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-005/00
A61B-017/06
A61F-002/04
출원번호
UP-0894876
(2004-07-19)
등록번호
US-7815590
(2010-11-08)
발명자
/ 주소
Cooper, Joel D.
출원인 / 주소
Broncus Technologies, Inc.
대리인 / 주소
Levine Bagade Han LLP
인용정보
피인용 횟수 :
67인용 특허 :
250
초록▼
Devices and methods for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having chronic obstructive pulmonary disease. The methods and devices create channels in lung tissue and maintain the patency of these surgically created channels in
Devices and methods for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having chronic obstructive pulmonary disease. The methods and devices create channels in lung tissue and maintain the patency of these surgically created channels in tissue. Maintaining the patency of the channels allows air to pass directly out of the lung tissue which facilitates the exchange of oxygen ultimately into the blood and/or decompresses hyper-inflated lungs.
대표청구항▼
The invention claimed is: 1. A method for treating a lung, the method comprising: selecting a treatment site in an airway of the lung; creating a hole in an airway wall of the airway by inserting a piercing member into the airway wall; removing the piercing member from the airway wall; locating the
The invention claimed is: 1. A method for treating a lung, the method comprising: selecting a treatment site in an airway of the lung; creating a hole in an airway wall of the airway by inserting a piercing member into the airway wall; removing the piercing member from the airway wall; locating the hole with a balloon catheter by probing the airway wall with a guide body on the balloon catheter, where the guide body has a rounded front surface to locate the hole without dragging on the airway tissue; inserting the guide body into the hole, where the guide body includes a resistance surface located proximal to the rounded front surface; temporarily anchoring the balloon catheter in the hole using the resistance surface of the guide body; and expanding the hole in the airway wall with the balloon catheter. 2. The method of claim 1, where selecting the treatment site comprises detecting the presence or absence of a blood vessel near the treatment site using ultrasound to avoid the blood vessel. 3. The method of claim 1, where the piercing member comprises an object selected from the group consisting of a needle, a cannula, a blade, a tube, and a rod. 4. The method of claim 1, where expanding the hole comprises partially expanding the hole with the balloon catheter, the method further comprising inserting an implant within the partially expanded hole. 5. The method of claim 4, further comprising fully expanding the hole by expanding the implant. 6. The method of claim 5, where expanding comprises partially expanding the hole by inserting the implant in the hole, the method further comprising fully expanding the hole by expanding the implant within the hole. 7. The method of claim 1 where selecting the treatment site comprises visually selecting the treatment site using a bronchoscope. 8. The method of claim 1, where selecting the treatment site comprises a step for determining the presence or absence of a blood vessel adjacent to the treatment site to avoid the blood vessel. 9. The method of claim 1, further comprising delivering a bio-active composition to the treatment site. 10. The method of claim 9, where the bio-active composition consists of a composition selected from the group consisting of antimetabolites, antithrobotics anticoagulants, antiplatelet agents, thorombolytics, antiproliferatives, antinflammatories, hyperplasia inhibiting agents, smooth muscle cell inhibitors, growth factors, growth factor inhibitors, cell adhesion inhibitors, cell adhesion promoters, neointimal tissue enhancing drugs, analgesics, anticonvulsives, anti-infectives, antineoplastics, histamine 2 antagonists, steroids, non-steroidal anti-inflammatories, hormones, immunomodulators, mast cell stabilizers, nucleoside analogues, respiratory agents, antihypertensives, antihistamines, ACE inhibitors, cell growth factors, nerve growth factors, anti-angiogenic agents, angiogenesis inhibitors, tissue irritants, cytotoxic agents, and metals, or a combination thereof. 11. The method of claim 9, where the bio-active composition comprises an agent selected from the group consisting of paclitaxel, rapamycin, sirolimus, everolimus, mitomycin, dactinomycin, and analogs or derivatives thereof. 12. The method of claim 9, further comprising deploying an implant into the hole. 13. The method of claim 12, where delivering the bio-active agent is carried by the implant. 14. The method of claim 1, further comprising delivering an implant to the hole using a delivery device, where the implant is visually distinct from the delivery device by color or reflection when viewed through a scope-type device, and using the visual distinction to aid in placement of the implant. 15. The method of claim 1, where the guide body comprises a shape selected from the shapes consisting of a tapered shape, rounded shape, partially-spherical shape, elliptical shape, prolate shape, cone-shape, and triangular shape. 16. The method of claim 1, where the guide body includes more than one resistance surface. 17. The method of claim 1, where the piercing member is advanceable through the guide body. 18. The method of claim 1, where the guide body includes a lumen terminating at the surface of the guide body. 19. The method of claim 1, where the front surface of the guide body comprise a distal spherical surface of the guide body and where the resistance surface comprises a proximal spherical surface of the guide body. 20. The method of claim 1, where the resistance surface is adjacent to an area of reduced diameter that allows the guide body to temporarily anchor the balloon catheter in the hole. 21. The method of claim 1, where the resistance surface comprises an area of increased surface roughness. 22. The method of claim 1, where the resistance surface increases resistance to removal of the guide body from the hole to temporarily anchor the balloon catheter in the hole. 23. A method for treating a lung, the method comprising: selecting a treatment site in an airway of the lung; detecting the presence or absence of a blood vessel near the treatment site to avoid the blood vessel; creating a hole in an airway wall of the airway by inserting a piercing member into the airway wall; locating the hole with a balloon catheter by probing the airway wall with a guide body on the balloon catheter, where the guide body has a rounded front surface to locate the hole without dragging on the airway tissue; inserting the guide body into the hole, where the guide body includes a resistance surface located proximal to the rounded front surface; temporarily anchoring the balloon catheter in the hole using the resistance surface of the guide body; and expanding the hole in the airway wall with the balloon catheter.
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