초록 ▼

The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution

The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution that contains olanexidine and at least an equimolar amount of gluconic acid, and substantially contains neither an acid other than gluconic acid nor a salt of the acid other than gluconic acid.

대표청구항 ▼

The invention claimed is: 1. An aqueous solution containing 1-(3,4-dichlorobenzyl)-5-octylbiguanide, at least an equimolar amount of gluconic acid, a polyalkylene glycol selected from the group consisting of polyethylene-polypropylene glycol and polyethylene glycol, and wherein the concentration of

The invention claimed is: 1. An aqueous solution containing 1-(3,4-dichlorobenzyl)-5-octylbiguanide, at least an equimolar amount of gluconic acid, a polyalkylene glycol selected from the group consisting of polyethylene-polypropylene glycol and polyethylene glycol, and wherein the concentration of an acid other than gluconic acid and a salt of the acid other than gluconic acid is not more than approximately 0.05% (W/V), wherein the concentration of 1-(3,4-dichlorobenzyl)-5-octylbiguanide is 0.1 to 20% (W/V), and the concentration of polyalkylene glycol is 0.01 to 10% (W/V). 2. The aqueous solution according to claim 1, wherein the concentration of 1-(3,4-dichlorobenzyl)-5-octylbiguanide is 10 to 20% (W/V). 3. The aqueous solution according to claim 1, wherein the polyalkylene glycol is a polyethylene-polypropylene glycol. 4. The aqueous solution according to claim 1, wherein the polyalkylene glycol is a polyethylene-polypropylene glycol having a polymerization degree of ethylene oxide of about 10 to 300, and a polymerization degree of propylene oxide of about 10 to 100. 5. A method of preparing the aqueous solution of claim 1, comprising; neutralizing or alkalizing an aqueous suspension of an acid addition salt of 1-(3,4-dichlorobenzyl)-5-octylbiguanide with an aqueous solution of an alkali to precipitate a solid, washing the precipitated solid with water, dissolving the washed solid in an aqueous gluconic acid solution that contains at least one mole of gluconic acid per mole of free olanexidine, and adding a polyalkylene glycol selected from the group consisting of polyethylene-polypropylene glycol and polyethylene glycol and, if necessary, water to the aqueous solution so that the concentration of 1-(3,4-dichlorobenzyl)-5-octylbiguanide is 0.1 to 20% (W/V) and the concentration of the polyalkylene glycol is 0.01 to 10% (W/V).