[미국특허]
Automatic continuous positive airway pressure treatment system with fast respiratory response
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
F16K-031/02
A61M-016/00
출원번호
UP-0498643
(2006-08-03)
등록번호
US-7845350
(2011-01-31)
발명자
/ 주소
Kayyali, Hani
Kolkowski, Brian M.
출원인 / 주소
Cleveland Medical Devices Inc.
대리인 / 주소
Kolkowski, Brian M.
인용정보
피인용 횟수 :
34인용 특허 :
8
초록▼
The present invention provides for a method and apparatus for providing continuous positive airway pressure for treating sleep apnea. The method comprising the steps of providing a breathing gas flow to a subject, measuring a respiratory characteristic of the subject, determining or estimating a pre
The present invention provides for a method and apparatus for providing continuous positive airway pressure for treating sleep apnea. The method comprising the steps of providing a breathing gas flow to a subject, measuring a respiratory characteristic of the subject, determining or estimating a preferable breathing gas flow for the subject based on wavelet analysis utilizing in part the respiratory characteristic of the subject; and preferably adjusting the breathing gas flow if the determined or estimated preferable breathing gas flow is different. This method and apparatus can be used in a number of applications including both clinical and home use in the form of CPAP for the treatment of sleep apnea or less preferably as a ventilator to assist in patient breathing.
대표청구항▼
What is claimed is: 1. An apparatus for delivering pressurized gas to an airway of a subject, the apparatus comprising: a gas flow generator adapted to provide a substantially continuous positive-pressure flow of gas to an airway of a subject; a conduit operatively coupled to the gas flow; a subjec
What is claimed is: 1. An apparatus for delivering pressurized gas to an airway of a subject, the apparatus comprising: a gas flow generator adapted to provide a substantially continuous positive-pressure flow of gas to an airway of a subject; a conduit operatively coupled to the gas flow; a subject interface operatively coupled to said conduit, the subject interface being adapted to communicate said conduit with the airway of the subject; one or more sensors adapted to detect a respiratory related characteristic of the subject having a signal, wherein the sensor or sensors are selected from the group comprising an airflow sensor, a pressure transducer that monitors the subject's breathing, a respiratory effort sensor, or an expired end carbon dioxide sensor; and a processor operatively coupled to the gas flow generator and the one or more sensors, wherein the processor determines and controls the level of flow generated by the gas flow generator through the use of wavelet-based analysis of at least the signal received from the one or more sensors and the signal from the one or more sensors creates an observed signal, and the wavelet analysis applies a wavelet transform to both the observed signal and a reference data set, the reference data set representing or characterizing distinct respiratory states, to create statistical observed and reference data sets. 2. The apparatus in claim 1, wherein the processor uses wavelet analysis to produce a command signal to the gas flow generator that mimics the subject's respiration. 3. The apparatus in claim 1, further comprising a drug delivery module wherein the processor also uses wavelet analysis to produce a command signal to the drug delivery module to release a drug or other therapeutic substance. 4. The apparatus in claim 1, wherein the wavelet analysis applies a wavelet transform to create wavelet coefficients using either a discrete stationary wavelet transform or a wavelet packet transform. 5. The apparatus in claim 4, wherein the wavelet coefficients are obtained by convolution of the signal with a wavelet filter. 6. The apparatus in claim 1, wherein the signal corresponding to the subject's respiratory characteristic is compared to at least two sets of stored data representing or characterizing at least two known respiratory states. 7. An apparatus for delivering pressurized gas to an airway of a subject, comprising: a gas flow generator adapted to provide a substantially continuous positive-pressure flow of gas to an airway of a subject; a subject interface coupled to the gas flow generator to deliver a flow of breathing gas from the gas flow generator to the airway of the subject; a sensor that detects a fluid characteristic associated with the flow of breathing gas within the subject interface and outputs a signal corresponding to the fluid characteristic; a controller associated with the gas flow generator to control the flow of breathing gas delivered to a subject; and processing means, adapted to receive the signal output from the sensor, to produce a command signal as a product of wavelet-based analysis of the fluid characteristic during a subject's breathing cycle, wherein the processing means provides the command signal to the gas flow controller to vary the flow of breathing gas with fluctuations of the fluid characteristic and the signal from the sensor creates an observed signal, the wavelet analysis applies a wavelet transform to both the observed signal and a reference data set, the reference data set representing or characterizing distinct respiratory states, to create statistical observed and reference data sets. 8. The apparatus in claim 7, wherein the processor uses wavelet analysis to produce a command signal to the gas flow generator that mimics the subject's respiration. 9. The apparatus in claim 7, further comprising a drug delivery module wherein the processor also uses wavelet analysis to produce a command signal to the drug delivery module to release a drug or other therapeutic substance. 10. The apparatus in claim 7, wherein the wavelet analysis applies a wavelet transform to create wavelet coefficients using either a discrete stationary wavelet transform or a wavelet packet transform. 11. The apparatus in claim 10, wherein the wavelet coefficients are obtained by convolution of the signal with a wavelet filter. 12. The apparatus in claim 7, wherein the signal corresponding to the subject's respiratory characteristic is compared to at least two sets of stored data representing at least two known respiratory states, the states being non-apneic and apneic. 13. A method of providing continuous positive airway pressure for treating sleep apnea comprising the steps of: providing a substantially continuous positive-pressure breathing gas flow to a subject; measuring a respiratory characteristic of the subject using a sensor or sensors selected from the group comprising an airflow sensor, a pressure transducer that monitors the subject's breathing, a respiratory effort sensor, or an expired end carbon dioxide sensor; determining or estimating a preferable breathing gas flow for the subject based on wavelet analysis utilizing in part the respiratory characteristic of the subject; and adjusting the breathing gas flow if the determined or estimated preferable breathing gas flow is different and the wavelet analysis is applied to the measured respiratory characteristic of the subject and to a reference data set, the reference data set representing or characterizing distinct respiratory states, to create statistical observed and reference data sets. 14. The method in claim 13, wherein the determined or estimated preferable gas flow for the subject uses wavelet analysis to adjust the breathing gas flow to the subject that mimics the subject's respiration. 15. The method in claim 13, wherein the wavelet analysis applies a wavelet transform to create wavelet coefficients using either a discrete stationary wavelet transform or a wavelet packet transform. 16. The method in claim 15, wherein the wavelet coefficients are obtained by convolution of the signal with a wavelet filter. 17. The method in claim 13, wherein the subject's respiratory characteristic is compared to at least two sets of stored data representing at least two known respiratory states, the states being non-apneic and apneic, to estimate or determine the preferable breathing gas flow for the subject.
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