IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
UP-0441276
(2006-05-25)
|
등록번호 |
US-7845499
(2011-01-31)
|
발명자
/ 주소 |
- Higgins, Joel C.
- Swift, Matthew
- Gordon, Nathan
- Hecker, Barry F.
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
62 인용 특허 :
306 |
초록
▼
An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be use
An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.
대표청구항
▼
What is claimed is: 1. A system for separating and extracting selected fractions from a container, the system comprising: a separation system, including: a first separation member having a first density; a second separation member having a second density; a connection member having a wall extending
What is claimed is: 1. A system for separating and extracting selected fractions from a container, the system comprising: a separation system, including: a first separation member having a first density; a second separation member having a second density; a connection member having a wall extending a distance and operably interconnecting said first separation member and said second separation member, the wall having an internal surface defining an internal passage and an external surface; a first collection face defined by said first separation member; wherein at least one of said first separation member, said second separation member, or both move along said external surface of said connection member; wherein a selected fraction is operable to be collected in said first collection face between said first separation member and said second separation member, and accessed with the internal passage. 2. The system of claim 1, further comprising: an extraction member; wherein said extraction member is operable to engage a portion of said connection member and provide a vacuum force through said internal passage of said connection member to assist in extraction of the selected fraction collected in said collection face. 3. The system of claim 1, further comprising: a container; an extraction port formed through the container to allow access to the interior of the collection face from an exterior of the container; and an extraction member that interconnects said extraction port and said connection member. 4. The system of claim 3, wherein said extraction member includes a flexible tube interconnecting said extraction port and said connection member. 5. The system of claim 2, further comprising: a container into which said separation system is placed; wherein said extraction member is operable to maintain a connection with said connection member while said separation system moves within said container, and/or while said first separation member, said second separation member, or both move along said external surface of said connection member. 6. The system of claim 5, wherein said connection member is operable to move within the container and relative to at least one of said first separation member or said second separation member or both and maintain a connection with said extraction member. 7. The system of claim 2, wherein said extraction member includes a tube defining a longitudinal axis that is substantially rigid along the longitudinal axis; wherein said extraction member is operable to be connected with said connection member directly from an extraction syringe. 8. The system of claim 1, further comprising: an extraction instrument operable to be connected with said connection member to withdraw a selected volume from between said first separation member and said second separation member through said internal passage. 9. The system of claim 8, wherein said extraction instrument includes a syringe and a tube extending therefrom. 10. The system of claim 9, wherein said tube includes a longitudinal axis; wherein said tube is substantially rigid along said longitudinal axis. 11. The system of claim 8, wherein said first separation member, said second separation member, or combinations thereof include a buoy moveable within the container; wherein said extraction instrument is operable to connect with said connection member when said connection member is at any position within the container, wherein said tube of said extraction instrument connects directly with a connection portion of said connection member at least by expanding over said connection portion of said connection member. 12. The system of claim 8, further comprising: an extraction port extending from the container; wherein at least a portion of said extraction instrument substantially permanently interconnects said extraction port and said connection member. 13. The system of claim 12, wherein said extraction member defines a throughbore therethrough operable to allow access to an extraction bore extending from said internal passage to a collection volume between said first separation member and said second separation member from said extraction port. 14. The system of claim 1, further comprising: an extraction instrument; wherein said extraction instrument is operable to apply at least a portion of the selected fraction onto an anatomy. 15. The system of claim 14, further comprising: a second component different from said selected fractions; and a first application system; wherein said second component and said selected fraction are operable to be mixed and applied with the first application system. 16. The system of claim 15, further comprising: a second application apparatus; wherein at least one of the extraction instrument, the first application system, of combinations thereof and the second application apparatus are operable to apply at least the selected fraction onto an anatomy simultaneously with the second component. 17. The system of claim 1, wherein said first separation member has an exterior surface that includes a first separation face that is convex and has a first angle; wherein said second separation member has a second exterior surface that includes a second separation face that is concave and has a second angle complementary to said first angle; wherein said connection member includes a catch portion having a surface extending from said connection member to contact said first separation member to limit movement of said first separation member along said connection member. 18. A system for separating and extracting selected fractions from a container, the system comprising: a separation system, including: a connection member extending a length between a first end and a second end; a first separation member having a first density and moveable along said length of said connection member; a second separation member having a second density different than said first density and fixed near said second end of said connection member; wherein said first separation member is operable to move relative to said second separation member along said length of said connection member; a collection volume defined between a first collection face of said first separation member and a second collection face of said second separation member; wherein a first selected fraction of the selected fractions is operable to be collected from said collection volume. 19. The system of claim 18, wherein the second density is greater than the first density. 20. The system of claim 19, further comprising: a connection portion extending from said connection member; and a connection member bore defined by an internal wall of said connection member that extends through the connection member and connects with the connection portion to allow permanent access to the collection volume though the connection member and the first separation member. 21. The system of claim 20, further comprising: a flexible tube connecting said connection portion and a platelet rich plasma portion of the container; wherein the first selected fraction is operable to be drawn through the flexible tube from the collection volume. 22. The system of claim 21, further comprising: an extraction port having a member extending from the container; wherein the flexible tube extends from the connection portion to the extraction port and interconnects the extraction port and the connection portion; wherein the flexible tube maintains the interconnection during use of the system. 23. The system of claim 22, further comprising: an extraction instrument operable to be connected with said extraction port to withdraw a selected volume from said collection volume between said first separation member and said second separation member. 24. The system of claim 23, wherein said extraction instrument includes a syringe. 25. The system of claim 20, further comprising: a catch portion including a surface extending away from and connected to an exterior of the connection member operable to engage the first separation member. 26. The system of claim 25, wherein said first separation member contacts said catch portion in a first direction along said connection member and contacts said second separation member in a second direction along said connection member. 27. A system for separating and extracting selected fractions from a container, the system comprising: a first separation member and a second separation member interconnected with a connection member having a throughbore through the connection member; a collection volume formed between the first separation member and the second separation member within the container; a tube connected to a connection portion of the connection member an extraction system operably connectable to the tube to extract at least one of the selected fractions from the collection volume; and an extraction port extending through a wall of the container to connect the extraction system to form a passage to the collection volume through the connection member; wherein at least a portion of at least one of the selected fractions is contained within the collection volume after a centrifugation of said first separation member, said second separation member, and said connection member within the container; wherein the tube is substantially permanently connected to said connection portion to allow access to the collection area between the first separation member and the second separation member; wherein said first separation member has a first density and said second separation member has a second density that is higher than said first density; wherein the first separation member has a first collection face and the second separation member has a second collection face; wherein the first collection face is a convex surface having a first angle and the second collection face is a concave surface having a second angle, where the first angle and the second angle are substantially complementary. 28. The system of claim 27, wherein the first separation member is operable to move along the connection member to allow the first collection face to mate with the second collection face of the second separation member. 29. The system of claim 28, further comprising: a container, and a catch on said connection member, wherein said first separation member has a first exterior wall defining a first buoy within said container and said second separation member has a second exterior wall defining a second buoy in said container; wherein said first buoy and said second buoy move independently of each other along said connection member; wherein said first buoy is operable to contact said catch.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.