This invention is an improved tissue-localizing device with an electrically energized locator element for fixedly yet removal marking a volume of tissue containing a suspect region for excision. The electrical energizing of the locator element facilitates the penetration of the locator element in to
This invention is an improved tissue-localizing device with an electrically energized locator element for fixedly yet removal marking a volume of tissue containing a suspect region for excision. The electrical energizing of the locator element facilitates the penetration of the locator element in to subject's tissue and minimizes resistance due to dense or calcified tissues. At least one locator element is deployed into tissue and assumes a predetermined curvilinear shape to define a tissue border containing a suspect tissue region along a path. Multiple locator elements may be deployed to further define the tissue volume along additional paths defining the tissue volume border that do not penetrate the volume. Delivery of electric cut-rent may be achieved through monopolar or bipolar electronic configuration depending on design needs. Various energy sources, e.g, radio frequency, microwave or ultrasound, may be implemented in this energized tissue-localizing device.
대표청구항▼
We claim the following: 1. A tissue-localizing device comprising: a sleeve having a lumen; an insulating layer at least partially covering an outer surface of the sleeve; a locator element at least partially disposed in the lumen of the sleeve in a slidable manner, the locator element having a dist
We claim the following: 1. A tissue-localizing device comprising: a sleeve having a lumen; an insulating layer at least partially covering an outer surface of the sleeve; a locator element at least partially disposed in the lumen of the sleeve in a slidable manner, the locator element having a distal portion and a distal end, the locator element further having at least a first surface and a second surface; a first electrically conductive surface region disposed at the distal end of the locator element and at least partially on the first surface and at least partially on the second surface; and at least a second electrically conductive surface region disposed at least partially along a length of the distal portion of the locator element and at least partially on the first surface and at least partially on the second surface, the locator element further adapted to penetrate tissue so that the distal portion of the locator element forms at least a partial loop that defines a volume of tissue when the locator element is deployed in tissue. 2. The tissue-localizing device of claim 1, wherein the first electrically conductive surface region is electrically isolated from the second electrically conductive surface region. 3. The tissue-localizing device of claim 1, further comprising: an electric power supply, the power supply having a current output connection and an electric ground connection; a first electrically conductive path connecting the first electrically conductive surface region to the current output connection of the power supply; and a second electrically conductive path connecting the second electrically conductive surface region to the electric ground connection of the power supply. 4. The tissue-localizing device of claim 3, wherein each of the first and second electrically conductive paths comprise an electrically conductive wiring embedded in the locator element. 5. The tissue-localizing device of claim 1, wherein the locator element comprises a non-conductive super-elastic polymer. 6. The tissue-localization device of claim 1, wherein the first electrically conductive surface region is positively charged and the second electrically conductive surface region is negatively charged. 7. A tissue-localizing device comprising: a sleeve having a lumen; an insulating layer at least partially covering an outer surface of the sleeve; a locator element at least partially disposed in the lumen of the sleeve in a slidable manner, the locator element having a distal portion and a distal end; a first electrically conductive surface region disposed at least partially on a first surface of the locator element and at least partially on a second surface of the locator element, the second surface disposed at the distal end of the locator element; and at least a second electrically conductive surface region disposed at least partially on the first surface of the locator element and at least partially on a third surface of the locator element, the locator element further adapted to penetrate tissue so that the distal portion of the locator element forms at least a partial loop that defines a volume of tissue when the locator element is deployed in tissue. 8. The tissue-localizing device of claim 7, wherein the second surface is disposed at an angle relative to the third surface. 9. The tissue-localizing device of claim 7, wherein the distal end of the locator element has a sharp edge. 10. The tissue-localizing device of claim 7, further comprising: an electric power supply, the power supply having a current output connection and an electric ground connection; a first electrically conductive path connecting the first electrically conductive surface region to the current output connection of the power supply; and a second electrically conductive path connecting the second electrically conductive surface region to the electric ground connection of the power supply. 11. The tissue-localizing device of claim 10, further comprising: at least a third and fourth electrically conductive surface region disposed at a proximal end of the locator element, the third electrically conductive surface region configured to connect the first electrically conductive path to the output connection of the power supply and the fourth electrically conductive surface region configured to connect the second electrically conductive path to the electric ground connection of the power supply. 12. A locator element for use in a tissue-localizing device for deployment in tissue, the locator element comprising: a non-conductive body portion defining at least a first surface and a second surface; a first electrically conductive surface region disposed at a distal end of the locator element and at least partially on the first surface and at least partially on the second surface; and at least a second electrically conductive surface region disposed at least partially along a length of a distal portion and at least partially on the first surface and at least partially on the second surface, the locator element further adapted to penetrate tissue so that the distal portion of the locator element forms at least a partial loop that defines a volume of tissue when the locator element is deployed in tissue. 13. The locator element of claim 12, wherein the non-conductive body portion further defines at least a third surface, wherein at least one of the first and second electrically conductive surface regions are disposed at least partially on the third surface. 14. The locator element of claim 13, wherein the third surface is disposed at an angle relative to the second surface. 15. The locator element of claim 13, wherein the third surface is defined at a distal end of the non-conductive body portion. 16. The locator element of claim 12, further comprising: an electric power supply, the power supply having a current output connection and an electric ground connection; a first electrically conductive path connecting the first electrically conductive surface region to the current output connection of the power supply; and a second electrically conductive path connecting the second electrically conductive surface region to the electric ground connection of the power supply. 17. The locator element of claim 16, further comprising: at least a third and fourth electrically conductive surface region disposed at a proximal end of the locator element, the third electrically conductive surface region configured to connect the first electrically conductive path to the output connection of the power supply and the fourth electrically conductive surface region configured to connect the second electrically conductive path to the electric ground connection of the power supply. 18. A tissue-localizing device comprising: a sleeve having a lumen; an insulating layer at least partially covering an outer surface of the sleeve; a locator element comprising a non-conductive super-elastic polymer, the locator element at least partially disposed in the lumen of the sleeve in a slidable manner, the locator element having a distal portion and a distal end, the locator element further having at least a first surface and a second surface; a first electrically conductive surface region disposed at least partially on the first surface and at least partially on the second surface; and at least a second electrically conductive surface region disposed at least partially on the first surface and at least partially on the second surface, the locator element further adapted to penetrate tissue so that the distal portion of the locator element forms at least a partial loop that defines a volume of tissue when the locator element is deployed in tissue. 19. A tissue-localizing device comprising: a sleeve having a lumen; an insulating layer at least partially covering an outer surface of the sleeve; a locator element at least partially disposed in the lumen of the sleeve in a slidable manner, the locator element having a distal portion and a distal end; a first electrically conductive surface region disposed at least partially on a first surface of the locator element and at least partially on a second surface of the locator element; and at least a second electrically conductive surface region disposed at least partially on the first surface of the locator element and at least partially on a third surface of the locator element, the second surface disposed at an angle relative to the third surface, the locator element further adapted to penetrate tissue so that the distal portion of the locator element forms at least a partial loop that defines a volume of tissue when the locator element is deployed in tissue. 20. A tissue-localizing device comprising: a sleeve having a lumen; an insulating layer at least partially covering an outer surface of the sleeve; a locator element at least partially disposed in the lumen of the sleeve in a slidable manner, the locator element having a distal portion and a distal end; a first electrically conductive surface region disposed at least partially on a first surface of the locator element and at least partially on a second surface of the locator element; at least a second electrically conductive surface region disposed at least partially on the first surface of the locator element and at least partially on a third surface of the locator element, the locator element further adapted to penetrate tissue so that the distal portion of the locator element forms at least a partial loop that defines a volume of tissue when the locator element is deployed in tissue; an electric power supply, the power supply having a current output connection and an electric ground connection; a first electrically conductive path connecting the first electrically conductive surface region to the current output connection of the power supply; a second electrically conductive path connecting the second electrically conductive surface region to the electric ground connection of the power supply; and at least a third and fourth electrically conductive surface region disposed at a proximal end of the locator element, the third electrically conductive surface region configured to connect the first electrically conductive path to the output connection of the power supply and the fourth electrically conductive surface region configured to connect the second electrically conductive path to the electric ground connection of the power supply. 21. A locator element for use in a tissue-localizing device for deployment in tissue, the locator element comprising: a non-conductive body portion defining at least a first surface and a second surface; a first electrically conductive surface region disposed at least partially on the first surface and at least partially on the second surface; and at least a second electrically conductive surface region disposed at least partially on the first surface and at least partially on the second surface, the locator element further adapted to penetrate tissue so that a distal portion of the locator element forms at least a partial loop that defines a volume of tissue when the locator element is deployed in tissue, wherein the non-conductive body portion further defines at least a third surface disposed at an angle relative to the second surface, wherein at least one of the first and second electrically conductive surface regions are disposed at least partially on the third surface. 22. A locator element for use in a tissue-localizing device for deployment in tissue, the locator element comprising: a non-conductive body portion defining at least a first surface and a second surface; a first electrically conductive surface region disposed at least partially on the first surface and at least partially on the second surface; at least a second electrically conductive surface region disposed at least partially on the first surface and at least partially on the second surface, the locator element further adapted to penetrate tissue so that a distal portion of the locator element forms at least a partial loop that defines a volume of tissue when the locator element is deployed in tissue; an electric power supply, the power supply having a current output connection and an electric ground connection; a first electrically conductive path connecting the first electrically conductive surface region to the current output connection of the power supply; a second electrically conductive path connecting the second electrically conductive surface region to the electric ground connection of the power supply; and at least a third and fourth electrically conductive surface region disposed at a proximal end of the locator element, the third electrically conductive surface region configured to connect the first electrically conductive path to the output connection of the power supply and the fourth electrically conductive surface region configured to connect the second electrically conductive path to the electric ground connection of the power supply.
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