초록 ▼

Disclosed are methods and apparatus for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can also include a treatment dosing system to infuse or inject a treatment drug (e.g. insulin or glucose) and provide glycemic control. The dose of the tre

Disclosed are methods and apparatus for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can also include a treatment dosing system to infuse or inject a treatment drug (e.g. insulin or glucose) and provide glycemic control. The dose of the treatment drug may be based on the concentration of the analyte or the average value for the concentration of the analyte and/or the rate of change of the value of the concentration of the analyte.

대표청구항 ▼

What is claimed is: 1. An analyte detection and treatment dosing system comprising:a fluid transport network configured to provide fluid communication with a body fluid in a patient through a patient end;a body fluid analyzer accessible via the fluid transport network, the body fluid analyzer config

What is claimed is: 1. An analyte detection and treatment dosing system comprising:a fluid transport network configured to provide fluid communication with a body fluid in a patient through a patient end;a body fluid analyzer accessible via the fluid transport network, the body fluid analyzer configured to measure a characteristic of at least one analyte in the body fluid and determine a concentration of the at least one analyte from the measured characteristic;at least one pump system coupled to the fluid transport network, the pump system having a sampling mode in which the pump system is operable to withdraw a sample of bodily fluid from the patient end and transport said sample of bodily fluid toward the body fluid analyzer, and an infusion mode in which the pump system is operable to transport an infusion fluid to the patient; anda treatment dosing system in communication with the body fluid analyzer, said treatment dosing system including a treatment dosing protocol stored in a computer memory and configured to automatically determine a recommended dose of an infusion fluid configured to provide glycemic control, wherein the treatment dosing system determines the recommended dose based at least in part on the measured concentration of the analyte and the stored treatment dosing protocol,wherein the treatment dosing system is configured to:provide signals to a control system that is configured to vary the pump rate of the at least one pump system to deliver the recommended dose of the infusion fluid to the patient, andwherein the treatment dosing system is configured to provide signals to a control system to automatically and completely stop the delivery of the infusion fluid if the measured concentration of the analyte is below a certain threshold.