초록 ▼

A collection container and a method for collecting a biological sample, particularly whole blood, includes at least one stabilizing agent in an amount effective to stabilize and inhibit protein degradation and/or fragmentation. The stabilizing agent is able to stabilize proteases in the biological s

A collection container and a method for collecting a biological sample, particularly whole blood, includes at least one stabilizing agent in an amount effective to stabilize and inhibit protein degradation and/or fragmentation. The stabilizing agent is able to stabilize proteases in the biological sample, particularly at the point of collection, by inhibiting protein degradation and/or fragmentation in the sample when the sample is stored. The stabilizing agent includes one or more protease inhibitors.

대표청구항 ▼

What is claimed is: 1. A sterile and evacuated tube for collecting and stabilizing whole blood or a component thereof, comprisinga first end and a second end and at least one interior wall defining a reservoir portion for receiving the blood, wherein said reservoir comprises at least one antioxidant

What is claimed is: 1. A sterile and evacuated tube for collecting and stabilizing whole blood or a component thereof, comprisinga first end and a second end and at least one interior wall defining a reservoir portion for receiving the blood, wherein said reservoir comprises at least one antioxidant and a protein stabilization agent comprising at least two lyophilized protease inhibitors, wherein a first inhibitor is an inhibitor of a serine protease and a second inhibitor is an inhibitor of another class of protease; anda closure pierceable by a needle for supplying blood to said reservoir.