[특허]Handheld and portable microfluidic device to automatically prepare nucleic acids for analysis

Handheld and portable microfluidic device to automatically prepare nucleic acids for analysis 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	B01D-024/02
출원번호	US-0223095 (2005-09-09)
등록번호	US7988935 (2011-07-18)
발명자 / 주소	Yuan, Bob Aflaatooni, Nima
출원인 / 주소	MicroFluidic Systems, Inc.
대리인 / 주소	Haverstock & Owens LLP
인용정보	피인용 횟수 : 0 인용 특허 : 44

초록 ▼

A handheld and portable extraction device is directed to a microfluidic-based system to be used in the field to extract and purify an analyte, preferably a nucleic acid, from a fluid-based sample. Preferably, the fluid-based sample is water-based. The fluid-based sample can also be a biological fluid sample. The handheld and portable extraction device includes a syringe-like device coupled to a purification chip. The purification chip is preferably included within a chip block which is removable from the remaining portion of the handheld and portable extraction device. The analyte collected within the purification chip can be later removed and collected for analysis.

대표청구항 ▼

What is claimed is: 1. A handheld and portable device comprising:a. a device input opening to the handheld and portable device, the device input opening is configured to provide external access and to input an external fluid-based sample into the handheld and portable device;b. a single syringe-like apparatus, wherein the syringe-like apparatus is configured for drawing the fluid-based sample into the device, wherein the syringe-like apparatus includes means for storing the sample input into the device;c. first means for directing coupled to the device input opening and to the means for storing, wherein the first means for directing is configured to transport the sample from the device input opening to the means for storing to input the sample into the means for storing;d. means for extracting and purifying an analyte from the sample, wherein the means for extracting and purifying includes a purification chip having a plurality of pillars, each pillar coated with silicon oxide;e. second means for directing coupled to the means for storing and to the means for extracting and purifying, wherein the second means for directing is configured to transport the sample from the means for storing into the means for extracting and purifying, further wherein the first means for directing, the means for storing, the second means for directing, and the means for extracting and purifying are configured to transport the sample into the means for storing prior to the sample entering the means for extracting and purifying; andf. means for regulating coupled to the means for storing, wherein the means for regulating is configured to regulate a fluid flow rate of the sample through the means for extracting and purifying.

이 특허에 인용된 특허 (44)

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Graham Marshall D. (Framingham MA), Apparatus for acoustically removing particles from a magnetic separation matrix.
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Miller C David, Biochemical detection system for rapid determination of the presence of toxins, bacteria, and other substances.
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Hansmann Douglas D. ; Grace John P. ; Lowery Michael G. ; Oosta Gary M. ; Loomis Neil W. ; Shain Eric B. ; Schapira Thomas G., Devices and methods utilizing arrays of structures for analyte capture.
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Rubin,Stuart H.; Chen,Shu Ching, Distributed biohazard surveillance system and apparatus for adaptive aerosol collection and synchronized particulate sampling.
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Rubin,Stuart H., Distributed biohazard surveillance system and apparatus for adaptive collection and particulate sampling.
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Guzman,Norberto A., Electrophoresis apparatus having staggered passage configuration.
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Chang, Ronald; Christel, Lee A.; Kovacs, Gregory T. A.; McMillan, William A.; Northrup, M. Allen; Petersen, Kurt E.; Pourahmadi, Farzad; Young, Steven J.; Yuan, Robert; Dority, Douglas B., Heat exchanging, optically interrogated chemical reaction assembly.
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Smith,James C., Membrane filtered pipette tip.
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Lehmann,Volker, Method and arrangement for taking up a first medium, which is present in a first phase, into a capillary device.
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Miles Robin R. ; Belgrader Phillip ; Nasarabadi Shanavaz L., Micro-sonicator for spore lysis.
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Harrison, D. Jed; Andersson, Per E.; Arriaga, Edgar; Ocvirk, Gregor, Microchip based enzymatic analysis.
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Silcott,David B.; Fielding,Alexander J., Multi-spectral optical method and system for detecting and classifying biological and non-biological particles.
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Buck Gerald F. (Sherborn MA) Roberts John W. (Milford MA) Sable Steven (Franklin MA), Multiple step reagent delivery system.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
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연합인증

Handheld and portable microfluidic device to automatically prepare nucleic acids for analysis 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

이 특허에 인용된 특허 (44)

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연합인증

Handheld and portable microfluidic device to automatically prepare nucleic acids for analysis 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

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이 특허에 인용된 특허 (44)

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