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[미국특허] Detection and diagnosis of inflammatory disorders 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/53
출원번호 US-0198014 (2008-08-25)
등록번호 US7989173 (2011-07-18)
발명자 / 주소
  • Chen, Lieping
출원인 / 주소
  • The Johns Hopkins University
대리인 / 주소
    Pabst Patent Group LLP
인용정보 피인용 횟수 : 5  인용 특허 : 67

초록

Soluble H4 (sH4) levels have been discovered to correlate with the stage or severity of inflammatory disorders including autoimmune disorders. In particular, circulating levels of sH4 can be used as a diagnostic for determining the severity of an inflammatory disorder or the propensity for developin

대표청구항

I claim: 1. A method for determining the severity of an inflammatory disorder in a subject having or suspected of having an inflammatory disorder comprising(a) determining the level of soluble B7-H4 in a biological sample from a subject; and(b) comparing the level of soluble B7-H4 in the biological

이 특허에 인용된 특허 (67) 인용/피인용 타임라인 분석

  1. Sette Alessandro ; Gaeta Federico ; Grey Howard M. ; Sidney John ; Alexander Jeffrey L., Alteration of immune response using pan DR-binding peptides.
  2. Failli Amedeo A. (Princeton Junction NJ) Steffan Robert J. (Langhorne PA), Aminodiesters of rapamycin.
  3. Murphy,Kenneth P.; Watanabe,Norihiko; Murphy,Theresa L.; Yang,Jianfei, BTLA nucleic acids.
  4. Failli Amedeo A. (Princeton Junction NJ) Bleyman Oleg I. (Holland PA) Kao Wenling (Paoli PA) Abou-Gharbia Magid A. (Glen Mills PA), Carbamates of rapamycin.
  5. Skotnicki Jerauld S. (Allentown NJ) Palmer Yvette L. (Newtown PA) Kao Wenling (Paoli PA) Abou-Gharbia Magid A. (Glen Mills PA), Carbamates of rapamycin.
  6. Skotnicki Jerauld S. (Allentown NJ) Palmer Yvette L. (Newtown PA) Kao Wenling (Paoli PA) Abou-Gharbia Magid A. (Glen Mills PA), Carbamates of rapamycin.
  7. Mitcham, Jennifer L.; King, Gordon E.; Algate, Paul A., Compositions and methods for the therapy and diagnosis of ovarian cancer.
  8. Mitcham,Jennifer L.; King,Gordon E.; Algate,Paul A.; Fling,Steven P.; Retter,Marc W.; Fanger,Gary R.; Reed,Steven G., Compositions and methods for the therapy and diagnosis of ovarian cancer.
  9. Jennifer L. Mitcham ; Gordon E. King ; Paul A. Algate, Compositions and methods for therapy and diagnosis of ovarian cancer.
  10. Herzig Yaacov,ILX ; Sterling Jeff,ILX ; Veinberg Alex,ILX ; Sklarz Benjamin,ILX ; Lidor Ramy,ILX ; Bahar Eliezer,ILX, Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically a.
  11. Ladner Robert C. (3827 Green Valley Iamsville MD 21754), Computer based system and method for determining and displaying possible chemical structures for converting double- or m.
  12. Pantoliano Michael W. (Germantown MD) Ladner Robert C. (Ijamsville MD), Computer-based method for designing stablized proteins.
  13. Miller A. Dusty (Seattle WA), DNA constructs for retrovirus packaging cell lines.
  14. Rosen Jeffrey M. (Houston TX), DNA sequences to target proteins to the mammary gland for efficient secretion.
  15. Steiner Solomon (Mt. Kisco NY) Rosen Robert (Rochester NY), Delivery systems for pharmacological agents encapsulated with proteinoids.
  16. Collins Francis S. (Ann Arbor MI) Wilson James M. (Ann Arbor MI), Gene therapy vector for cystic fibrosis.
  17. Temin Howard M. (Madison WI) Watanabe Shinichi (Madison WI), Helper cell.
  18. Nelson Frances C. (Yardley PA) Schiehser Guy A. (Yardley PA), Hindered esters of rapamycin.
  19. Engleman Edgar G. (Atherton CA) Foung Steven K. H. (San Francisco CA) Grumet F. Carl (Stanford CA), Human-murine hybridoma fusion partner.
  20. Queen Cary L. (Los Altos CA) Co Man Sung (Cupertino CA) Schneider William P. (Mountain View CA) Landolfi Nicholas F. (Milpitas CA) Coelingh Kathleen L. (San Francisco CA) Selick Harold E. (Belmont CA, Humanized immunoglobulins.
  21. Queen Cary L. (Los Altos CA) Selick Harold E. (Belmont CA), Humanized immunoglobulins.
  22. Queen Cary L. (Los Altos CA) Selick Harold E. (Belmont CA), Humanized immunoglobulins.
  23. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.
  24. Woodle Martin C. (Menlo Park CA) Martin Francis J. (San Francisco CA) Yau-Young Annie (Los Altos CA) Redemann Carl T. (Walnut Creek CA), Liposomes with enhanced circulation time.
  25. Johnson Kevin Stuart,GBX ; Winter Gregory Paul,GBX ; Griffiths Andrew David,GBX ; Smith Andrew John Hammond,GBX ; Waterhouse Peter Michael,AUX, Methods for producing members of specific binding pairs.
  26. Winter Gregory Paul,GBX ; Johnson Kevin Stuart,GBX ; Griffiths Andrew David,GBX ; Smith Andrew John Hammond,GBX, Methods for producing members of specific binding pairs.
  27. Winter Gregory Paul,GBX ; Johnson Kevin Stuart,GBX ; Griffiths Andrew David,GBX ; Smith Andrew John Hammond,GBX, Methods for producing members of specific binding pairs.
  28. Jaffe Howard (Gaithersburg MD), Microencapsulation process.
  29. Paoletti Enzo (Delmar NY) Panicali Dennis (Averill Park NY), Modified vaccinia virus and methods for making and using the same.
  30. Holliger Kaspar-Philipp,GBX ; Griffiths Andrew David,GBX ; Hoogenboom Hendricus Renerus Jacobus Matheus,BEX ; Malmqvist Magnus,SEX ; Marks James David ; McGuinness Brian Timothy,GBX ; Pope Anthony Ri, Multivalent and multispecific binding proteins, their manufacture and use.
  31. Chen, Lieping, Nucleic acids encoding B7-H4, a T cell immunoregulatory molecule.
  32. Zhu Tianmin ; Lee Hyuk-Koo, Photocyclized rapamycin.
  33. Queen Cary L. (Los Altos CA) Schneider William P. (Mountain View CA) Selick Harold E. (Belmont CA), Polynucleotides encoding improved humanized immunoglobulins.
  34. Mathiowitz Edith (Brookline MA) Langer Robert S. (Somerville MA), Preparation of multiwall polymeric microcapsules.
  35. Oestberg Lars (Vienna ATX), Process for the production of human mono-clonal antibodies.
  36. Hoogenboom Hendricus R. J. M. (Cambridge GBX) Baier Michael (Frankfurt DEX) Jespers Laurent S. A. T. (Tervuren BEX) Winter Gregory P. (Cambridge GBX), Production of chimeric antibodies - a combinatorial approach.
  37. Platz Robert M. (Half Moon Bay CA) Winters Mark A. (Mountain View CA) Pitt Colin G. (Thousand Oaks CA), Pulmonary administration of granulocyte colony stimulating factor.
  38. Wong Jeffrey T.-F. (Hong Kong HKX) Tam Michael S.-C. (Shatin HKX), Pulmonary drug delivery system.
  39. Lonberg Nils (San Francisco CA) Kay Robert M. (San Francisco CA), Ransgenic non-human animals for producing heterologous antibodies.
  40. Hughes Philip F. (Chapel Hill NC) Musser John H. (Alameda CA), Rapamycin analog as immunosuppressant.
  41. Kao Wenling (Paoli PA) Vogel Robert L. (Stratford NJ) Musser John H. (Alameda CA), Rapamycin dimers.
  42. Waranis Robert P. (Chazy NY) Harrison Maureen M. (St. Albans VT) Leonard Thomas W. (Plattsburgh NY) Enever Robin P. (Rouses Point NY), Rapamycin formulation for IV injection.
  43. Nagi Arwinder S., Rapamycin formulations for oral administration.
  44. Winter Gregory P. (Cambridge GBX), Recombinant altered antibodies and methods of making altered antibodies.
  45. Paoletti Enzo (Albany NY), Recombinant poxvirus host range selection system.
  46. Paoletti Enzo (Albany NY), Recombinant poxvirus host range selection system.
  47. Paoletti Enzo (Albany NY), Recombinant poxvirus internal cores.
  48. Temin Howard M. (Madison WI) Dougherty Joseph P. (Madison WI), Recombination resistant retroviral helper cell and products produced thereby.
  49. Bank Arthur (Riverdale NY) Markowitz Dina G. (New York NY) Goff Stephen P. (Tenafly NJ), Retroviral packaging cell lines and process of using same.
  50. Wills John W. (Shreveport LA), Retrovirus-mediated secretion of recombinant products.
  51. Eaton,Dan L.; Filvaroff,Ellen; Gerritsen,Mary E.; Goddard,Audrey; Godowski,Paul J.; Grimaldi,J. Christopher; Gurney,Austin L.; Watanabe,Colin K.; Wood,William I., Secreted and transmembrane polypeptides and nucleic acids encoding the same.
  52. Ladner Robert C. (Ijamsville MD) Bird Robert E. (Rockville MD) Hardman Karl (Chevy Chase MD), Single polypeptide chain binding molecules.
  53. Ladner Robert C. (Ijamsville MD) Bird Robert E. (Rockville MD) Hardman Karl (Chevy Chase MD), Single polypeptide chain binding molecules.
  54. Chen, Lieping, T-cell immunoregulatory molecule.
  55. Deboer Herman A.,NLX ; Strijker Rein,NLX ; Heyneker Herbert L. ; Platenburg Gerard,NLX ; Lee Sang He,NLX ; Pieper Frank,NLX ; Krimpenfort Paul J. A.,NLX, Transgenic bovine.
  56. Lonberg Nils (San Francisco CA) Kay Robert M. (San Francisco CA), Transgenic non-human animals capable of producing heterologous antibodies.
  57. Lonberg Nils ; Kay Robert M., Transgenic non-human animals capable of producing heterologous antibodies.
  58. Lonberg Nils ; Kay Robert M., Transgenic non-human animals capable of producing heterologous antibodies.
  59. Lonberg Nils (San Francisco CA) Kay Robert M. (San Francisco CA), Transgenic non-human animals capable of producing heterologous antibodies of various isotypes.
  60. Lonberg Nils (San Francisco CA) Kay Robert M. (San Francisco CA), Transgenic non-human animals capable of producing heterologous antibodies of various isotypes.
  61. Lonberg Nils ; Kay Robert M., Transgenic non-human animals capable of producing heterologous antibodies of various isotypes.
  62. Lonberg Nils (Redwood City CA) Kay Robert M. (San Francisco CA), Transgenic non-human animals for producing heterologous antibodies.
  63. Lonberg Nils ; Kay Robert M., Transgenic non-human animals for producing heterologous antibodies.
  64. Lonberg Nils ; Kay Robert M., Transgenic non-human animals for producing heterologous antibodies.
  65. Meade Harry ; Ditullio Paul ; Pollock Daniel, Transgenic production of antibodies in milk.
  66. Lezdey, Darren; Lezdey, Jarett, Treatment of lupus erythematosus.
  67. Lee Hyuk-Koo ; Zhu Tianmin, Water soluble rapamycin esters.

이 특허를 인용한 특허 (5) 인용/피인용 타임라인 분석

  1. Podack, Eckhard R.; Rosenblatt, Joseph D.; Yamazaki, Koichi, Allogeneic cancer cell-based immunotherapy.
  2. Langermann, Solomon; Liu, Linda; Podojil, Joseph R.; Miller, Stephen D.; Marshall, Shannon, B7-H4 fusion proteins and methods of use thereof.
  3. Langermann, Solomon; Liu, Linda; Podojil, Joseph R.; Miller, Stephen D.; Marshall, Shannon, B7-H4 fusion proteins and methods of use thereof.
  4. Chen, Lieping, Detection and diagnosis of inflammatory disorders.
  5. Langermann, Solomon; Liu, Linda, Methods and compositions for the inhibition of transplant rejection.

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