초록 ▼

A tissue graft product includes at least one collagen layer comprised of submucosa or renal capsule tissue having slits therein to provide a mesh pattern which in turn establishes a graft structure that is highly deformable. The slits and mesh pattern provide for improved characteristics when utiliz

A tissue graft product includes at least one collagen layer comprised of submucosa or renal capsule tissue having slits therein to provide a mesh pattern which in turn establishes a graft structure that is highly deformable. The slits and mesh pattern provide for improved characteristics when utilized as a tissue graft and in particular an external wound care. Preferred devices have multiple submucosa, renal capsule or other collagenous extracellular matrix layers, providing a substantial and lasting scaffold for tissue ingrowth during wound treatment.

대표청구항 ▼

What is claimed is: 1. A medical product, comprising:a sterile package; anda sterile tissue graft product contained within said sterile package, said tissue graft product exhibiting a non-tubular, sheet form and being useful for treating an exuding open cutaneous wound, the sterile tissue graft prod

What is claimed is: 1. A medical product, comprising:a sterile package; anda sterile tissue graft product contained within said sterile package, said tissue graft product exhibiting a non-tubular, sheet form and being useful for treating an exuding open cutaneous wound, the sterile tissue graft product having a thickness extending between a top outermost surface of the sterile tissue graft product and a bottom outermost surface of the sterile tissue graft product, wherein an extracellular matrix material obtained from a biological tissue source spans the entirety of said thickness and has a plurality of slits therein providing a mesh pattern, said mesh pattern effective to provide an expansion ratio of at least about 1.2:1 to said extracellular matrix material in a hydrated condition, the extracellular matrix material including submucosa or renal capsule tissue retaining growth factors native to the biological tissue source and having a nucleic acid level of less than 5 micrograms per milligram.