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Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
  • C07H-021/04
출원번호 US-0270804 (2005-11-09)
등록번호 US-8158362 (2012-04-17)
발명자 / 주소
  • Helgadottir, Anna
  • Hákonarson, Hákon
  • Gulcher, Jeffrey R.
  • Gurney, Mark E.
출원인 / 주소
  • deCODE Genetics ehf.
대리인 / 주소
    Marshall, Gerstein & Borun LLP
인용정보 피인용 횟수 : 1  인용 특허 : 72

초록

Polymorphisms in the FLAP and LTA4H gene are shown by genetic association analysis to be susceptibility markers for myocardial infarction (MI) and ACS, as well as stroke and PAOD. Pathway targeting for treatment and diagnostic applications in identifying those who are at risk of developing MI, ACS,

대표청구항

1. A method of detecting an LTA4H haplotype associated with myocardial infarction (MI) risk in a human individual and assessing susceptibility to MI in said human individual, comprising assaying a nucleic acid-containing sample obtained from the human individual to detect therein the presence of an

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