$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Methods and products for analyzing polymers 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-021/64
  • C12Q-001/68
출원번호 US-0852968 (2001-05-10)
등록번호 US-8168380 (2012-05-01)
발명자 / 주소
  • Chan, Eugene Y.
출원인 / 주소
  • Life Technologies Corporation
인용정보 피인용 횟수 : 22  인용 특허 : 207

초록

Methods and products for analyzing polymers are provided. The methods include methods for determining various other structural properties of the polymers.

대표청구항

1. A method comprising: providing a nucleic acid, labeled with a unit specific marker, anddetecting, while the nucleic acid is moved relative to electromagnetic radiation by a tethered polymerase, at least one FRET-independent fluorescent signal emitted from the unit specific marker. 2. A method for

이 특허에 인용된 특허 (207)

  1. Menchen Steven M. (Fremont CA) Lee Linda G. (Palo Alto CA) Connell Charles R. (Redwood City CA) Hershey N. Davis (San Carlos CA) Chakerian Vergine (San Mateo CA) Woo Sam (Redwood City CA) Fung Steven, 4,7-dichlorofluorescein dyes as molecular probes.
  2. Blanco Luis (Madrid) Bernad Antonio (Madrid) Salas Margarita (Madrid ESX), f 상세보기
  • Blanco Luis (Madrid ESX) Bernad Antonio (Madrid ESX) Salas Margarita (Madrid ESX), f 상세보기
  • Bandman Olga ; Guegler Karl J. ; Corley Neil C. ; Shah Purvi, ATP-dependent RNA helicase protein.
  • Stewart Russell J., Active microtubule-based separations by kinesins.
  • Heller Michael J. (Encinitas CA) Tu Eugene (San Diego CA), Active programmable electronic devices for molecular biological analysis and diagnostics.
  • Hobbs ; Jr. Frank W. (Wilmington DE) Cocuzza Anthony J. (Wilmington DE), Alkynylamino-nucleotides.
  • Hobbs ; Jr. Frank W. (Wilmington DE) Trainor George L. (Wilmington DE), Alkynylamino-nucleotides.
  • Fung Steven (Palo Alto CA) Woo Sam L. (Redwood City CA) Smith Lloyd M. (South Pasadena CA), Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof.
  • Baker Brenda F. ; Cowsert Lex M., Antisense inhibition of ETs-2 expression.
  • Swartz Harold M. (Hanover NH) Goda Fuminori (Hanover NH) Walczak Tadeusz (Hanover NH) Liu Ke J. (Hanover NH), Apparatus and methodology for determining oxygen in biological systems.
  • Swartz Harold M. ; Goda Fuminori ; Walczak Tadeusz ; Liu Ke Jian ; Mader Karsten, Apparatus and methodology for determining oxygen tension in biological systems.
  • Ulmer, Kevin, Apparatus and methods for analyzing samples.
  • Ulmer,Kevin, Apparatus and methods for analyzing samples.
  • Herron James N. (Salt Lake City UT) Christensen Douglas A. (Salt Lake City UT) Wang Hsu-Kun (Salt Lake City UT) Caldwell Karin D. (Salt Lake City UT) Janatova Vera (Prague CSX) Huang Shao-Chie (Salt , Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays.
  • Van Gelder Ezra (Belmont CA) Liang Bee C. (Sunnyvale CA) Johnston Richard F. (Murphys CA) Loder ; Jr. Robert T. (Sunnyvale CA), Apparatus for measuring spatial distribution of fluorescence on a substrate.
  • Benson Scott Conrad ; Menchen Steven Michael ; Theisen Peter David ; Upadhya Krishna Gajanan ; Hauser Joan Dale, Aromatic-substituted xanthene dyes.
  • Benson Scott C. ; Menchen Steven M. ; Theisen Peter D. ; Hennessey Kevin M. ; Furniss Vergine C. ; Hauser Joan, Asymmetric benzoxanthene dyes.
  • Benson,Scott C.; Menchen,Steven M.; Theisen,Peter D.; Hennessey,Kevin M.; Furniss,Vergine C.; Hauser,Joan D., Asymmetric benzoxanthene dyes.
  • Smith Lloyd M. (Madison WI) Hood Leroy E. (Pasadena CA) Hunkapiller Michael W. (San Carlos CA) Hunkapiller Tim J. (Pasadena CA), Automated DNA sequencing technique.
  • Weiss Robert B. (Salt Lake City UT) Kimball Alvin W. (Salt Lake City UT) Gesteland Raymond F. (Salt Lake City UT) Ferguson F. Mark (Salt Lake City UT) Dunn Diane M. (West Valley City UT) Di Sera Leon, Automated hybridization/imaging device for fluorescent multiplex DNA sequencing.
  • Engelhardt Dean (New York NY) Rabbani Elazar (New York NY) Kline Stanley (Brooklyn NY) Stavrianopoulos Jannis G. (New York NY) Kirtikar Dollie (Elmhurst NY), Base moiety-labeled detectable nucleatide.
  • Haugland Richard P. (Eugene OR) Whitaker James E. (Eugene OR), Biological conjugates of fluorescent rhodol dyes.
  • Mathies Richard A. (Contra Costa County CA) Huang Xiaohua C. (Santa Clara County CA) Quesada Mark A. (San Francisco County CA), Capillary array confocal fluorescence scanner and method.
  • Kwiatkowski Marek,SEX, Chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation.
  • Baldarelli Richard ; Branton Daniel ; Church George ; Deamer David W. ; Akeson Mark ; Kasianowicz John, Characterization of individual polymer molecules based on monomer-interface interactions.
  • Church George ; Deamer David W. ; Branton Daniel ; Baldarelli Richard ; Kasianowicz John, Characterization of individual polymer molecules based on monomer-interface interactions.
  • Timothy J. Denison ; Alexis Sauer ; Jene Golovchenko ; Amit Meller ; Eric Brandin ; Daniel Branton, Characterization of individual polymer molecules based on monomer-interface interactions.
  • Ulmer Kevin M., Chemical biochemical and biological processing in thin films.
  • Kotewicz Michael L. (Columbia MD) Gerard Gary F. (Frederick MD), Cloned genes encoding reverse transcriptase lacking RNase H activity.
  • Windle Bradford E., Color imaging method for mapping stretched DNA hybridized with fluorescently labeled oligonucleotide probes.
  • Hsia Jen-Chang, Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules.
  • Hsia Jen-Chang, Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules.
  • Hsia Jen-Chang, Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules.
  • Hsia Jen-Chang, Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules.
  • Hsia Jen-Chang, Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules.
  • Hsia Jen-Chang, Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules.
  • Jen-Chang Hsia, Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules.
  • Hsia Jen-Chang, Compositions and methods utilizing nitroxides in combination with biocompatible macromolecules for ERI or MRI.
  • Vurek Gerald G. (Mountain View CA) Iyer Lokanathan M. (Edmonds WA) Scott James R. (Bothell WA), Compound optical probe employing single optical waveguide.
  • Kwiatkowski Marek,SEX, Compounds for protecting hydroxyls and methods for their use.
  • Kwiatkowski, Marek, Compounds for protecting hydroxyls and methods for their use.
  • Kwiatkowski,Marek, Compounds for protecting hydroxyls and methods for their use.
  • Ingemann Ole (Svendborg DKX), Container and closure having frangible opening means.
  • Narayanan, Narasimhachari, Cyanine dye compounds and labeling methods.
  • Oommen Abraham ; Roemer Steve, Cycle labeling and sequencing with thermostable polymerases.
  • Middendorf Lyle Richard ; Bruce Robert Clark ; Eckles Robert David, DNA Sequencing.
  • Glazer Alexander N. (Orinda CA) Benson Scott C. (Albany CA), DNA complexes with dyes designed for energy transfer as fluorescent markers.
  • Kambara Hideki (Hachiouji JPX) Okano Kazunori (Shiki JPX) Takahashi Satoshi (Kokubunji JPX) Nagai Keiichi (Higashiyamato JPX) Nishikawa Tetsuo (Itabashi JPX), DNA measuring method.
  • Bedford Ella ; Tabor Stanley ; Richardson Charles C., DNA polymerase with modified processivity.
  • Santamaria Pedro (Minneapolis MN) Boyce-Jacino Michael T. (Saint Paul MN) Barbosa Jose J. (Roseville MN) Rich Stephen S. (Saint Paul MN) Faras Anthony J. (Long Lake MN), DNA sequence-based HLA typing method.
  • Middendorf Lyle R. (Lincoln NE) Bruce Robert C. (Lincoln NE) Eckles Robert D. (Malcolm NE), DNA sequencing.
  • Middendorf Lyle R. (Lincoln NE) Bruce Robert C. (Lincoln NE) Eckles Robert D. (Malcolm NE), DNA sequencing.
  • Middendorf Lyle Richard ; Bruce Robert Clark ; Eckles Robert David, DNA sequencing.
  • Middendorf Lyle Richard ; Brumbaugh John, DNA sequencing.
  • Tabor Stanley (Cambridge MA) Richardson Charles C. (Chestnut Hill MA), DNA sequencing.
  • Middendorf Lyle Richard ; Brumbaugh John A., DNA sequencing and DNA terminators.
  • Koster Hubert (Concord MA), DNA sequencing by mass spectrometry.
  • Brenner Sydney (Cambridge GB2), DNA sequencing by stepwise ligation and cleavage.
  • Densham, Daniel Henry, DNA sequencing method.
  • Rosenthal Andre,GBX ; Brenner Sydney,GBX, DNA sequencing method.
  • Trainor George L. (Glen Mills PA), DNA sequencing method using acyclonucleoside triphosphates.
  • Tabor Stanley (Cambridge MA) Richardson Charles C. (Chestnut Hill MA), DNA sequencing with pyrophosphatase.
  • Nadeau James G. ; Pitner J. Bruce ; Linn C. Preston ; Schram James L., Detection of nucleic acids by fluorescence quenching.
  • Atwood Susan M. (Rush NY) Cummins Thomas J. (Rochester NY) Findlay John B. (Rochester NY), Diagnostic compositions, elements, methods and test kits for amplification and detection of retroviral DNA using primers.
  • Benson Scott Conrad ; Lam Joe Y. L. ; Upadhya Krishna Gajanan ; Radel Peggy Ann ; Zhen Weiguo ; Menchen Steven Michael, Dibenzorhodamine dyes.
  • Mathies Richard A. ; Glazer Alexander N. ; Lao Kaiqin ; Woolley Adam T., Electrochemical detector integrated on microfabricated capillary electrophoresis chips.
  • Lee Linda G. ; Spurgeon Sandra L. ; Rosenblum Barnett, Energy transfer dyes with enchanced fluorescence.
  • Lee Linda G. ; Spurgeon Sandra L. ; Rosenblum Barnett, Energy transfer dyes with enhanced fluorescence.
  • Carr Robert J. G. (Wayside ; Thorneydown Road ; Winterbourne Gunner Salisbury SP4 6LN GBX) Clarke David J. (Carefree Rivermead Idmiston Salisbury ; Wilts GBX) Atkinson Anthony (Twingley Winterbourne , Examination of objects of macromolecular size.
  • Macaulay John M. (Palo Alto CA) Searson Peter C. (Baltimore MD) Duboc ; Jr. Robert M. (Menlo Park CA) Spindt Christopher J. (Menlo Park CA), Fabrication of filamentary field-emission device, including self-aligned gate.
  • Conn Shepard (Metuchen NJ) Kushner Arnold (Queens NY), Fluid-expansible contraceptive tampon and applicator.
  • Ullman Edwin F. (Atherton CA) Schwarzberg Moshe (Palo Alto CA), Fluorescence quenching with immunological pairs in immunoassays.
  • Little Garrick Murray ; Raghavachari Ramesh ; Narayanan Narasimhachari ; Osterman Harry Leonard, Fluorescent cyanine dyes.
  • Mathies Richard A. (El Cerrito CA) Glazer Alexander (Orinda CA) Ju Jingyue (Berkeley CA), Fluorescent labels and their use in separations.
  • Hobbs ; Jr. Frank W. (Wilmington DE), Fluorescent reagents for the preparation of 5′-tagged oligonucleotides.
  • Gee Kyle R. ; Poot Martin ; Klaubert Dieter H. ; Sun Wei-Chuan ; Haugland Richard P. ; Mao Fei, Fluorinated xanthene derivatives.
  • Williams John G. K., Heterogeneous assay for pyrophosphate detection.
  • Mathies Richard A. (Contra Costa County CA) Peck Konan (Contra Costa County CA) Stryer Lubert (Santa Clara County CA), High sensitivity fluorescent single particle and single molecule detection apparatus and method.
  • Schneider,Thomas D.; Rubens,Denise, High speed parallel molecular nucleic acid sequencing.
  • Hueton Iain (Los Altos Hills CA) Van Gelder Ezra (Belmont CA), High-speed fluorescence scanner.
  • Bawendi Moungi ; Jensen Klavs F. ; Dabbousi Bashir O.,SAX ; Rodriguez-Viejo Javier,ESX ; Mikulec Frederic Victor, Highly luminescent color-selective materials and method of making thereof.
  • Bawendi Moungi ; Jensen Klavs F. ; Dabbousi Bashir O.,SAX ; Rodriguez-Viejo Xavier,ESX ; Mikulec Frederic Victor, Highly luminescent color-selective nano-crystalline materials.
  • Lal Preeti ; Hillman Jennifer L. ; Bandman Olga ; Shah Purvi ; Au-Young Janice ; Yue Henry ; Guegler Karl J. ; Corley Neil C., Human regulatory molecules.
  • Sasaki Yuji (Kawagoe JPX) Harada Yoshinori (Hatoyama JPX), Hydrogen bond labeling and base sequence determination methods for DNA or RNA.
  • Schwartz David C., Image processing and analysis of individual nucleic acid molecules.
  • Schwartz David C., Image processing and analysis of individual nucleic acid molecules.
  • Anderson Rolfe C. ; Lipshutz Robert J. ; Rava Richard P. ; Fodor Stephen P. A., Integrated nucleic acid diagnostic device.
  • James A. Laugharn, Jr. ; Robert A. Hess, Integrated sequencing device.
  • Laugharn ; Jr. James A. ; Hess Robert A., Integrated sequencing device.
  • Jones Douglas H., Iterative and regenerative DNA sequencing method.
  • Foote Robert S. (Oak Ridge TN), Large scale DNA microsequencing device.
  • Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA), Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof.
  • Mathies Richard A. (Contra Costa CA) Peck Konan (Contra Costa CA), Laser excited confocal microscope fluorescence scanner and method.
  • Ugelstad John (Trondheim NOX) Ellingsen Turid (Trondheim NOX) Berge Arvid (Trondheim NOX) Helgee Oskar B. (Mlnlycke SEX), Magnetic polymer particles and process for the preparation thereof.
  • Brenner Sydney (Cambridge GB2), Massively parallel sequencing of sorted polynucleotides.
  • Nova Michael P. ; Parandoosh Zahra ; Senyei Andrew E. ; Xiao Xiao-Yi ; David Gary S. ; Satoda Yozo ; Zhao Chanfeng ; Potash Hanan, Matrices with memories and uses thereof.
  • Stern David ; Fiekowsky Peter, Method and apparatus for detection of fluorescently labeled materials.
  • Sargent Jeannine P. (22270 Kendle St. Cupertino CA 95014) Marks Jeff (4730 Cielo Vista Way San Jose CA 95129), Method and apparatus for determining the sequence of polynucleotides.
  • Clements James G. (Stratham NH), Method and apparatus for forming a plurality of tracks in a flexible workpiece with a high energy particle.
  • Ishikawa Mitsuru (Hamamatsu JPX), Method and device for determining the location and number of fluorescent molecules.
  • Stavrianopoulos Jannis G. (New York NY) Kirtikar Dollie (Elmhurst NY) Johnston Kenneth H. (New York NY) Thalenfeld Barbara E. (New York NY), Method and structures employing chemically-labelled polynucleotide probes.
  • Seeger, Stefan, Method for DNA- or RNA-sequencing.
  • Stabinsky Yitzhak (Boulder CO), Method for derivitization of polynucleotides.
  • Livak Kenneth J. (San Jose CA) Flood Susan J. A. (Fremont CA) Marmaro Jeffrey (Foster City CA), Method for detecting nucleic acid amplification using self-quenching fluorescence probe.
  • Anazawa Takashi,JPX ; Okano Kazunori,JPX ; Uematsu Chihiro,JPX ; Kambara Hideki,JPX, Method for determining nucleic acids base sequence and apparatus therefor.
  • Goelet Philip ; Knapp Michael R. ; Anderson Stephen, Method for determining nucleotide identity through extension of immobilized primer.
  • Stemple,Derek L.; Armes,Niall A., Method for direct nucleic acid sequencing.
  • Holzrichter John F. (Berkeley CA) Siekhaus Wigbert J. (Berkeley CA), Method for identifying biochemical and chemical reactions and micromechanical processes using nanomechanical and electro.
  • Chu Steven (Stanford CA) Kron Stephen J. (Cambridge MA), Method for optically manipulating polymer filaments.
  • Middendorf Lyle Richard (Lincoln NE) Patonay Gabor (Stone Mountain GA), Method for preparing fluorescent-labeled DNA.
  • Jett James H. (Los Alamos NM) Keller Richard A. (Los Alamos NM) Martin John C. (Los Alamos NM) Moyzis Robert K. (Los Alamos NM) Ratliff Robert L. (Los Alamos NM) Shera E. Brooks (Los Alamos NM) Stewa, Method for rapid base sequencing in DNA and RNA.
  • Jett James H. (Los Alamos NM) Keller Richard A. (Los Alamos NM) Martin John C. (Los Alamos NM) Posner Richard G. (Los Alamos NM) Marrone Babetta L. (Los Alamos NM) Hammond Mark L. (Los Alamos NM) Sim, Method for rapid base sequencing in DNA and RNA with two base labeling.
  • Sessler Andrew M. (Oakland CA) Dawson John (Pacific Palisades CA), Method for sequencing DNA base pairs.
  • Cheeseman Peter C. (Palo Alto CA), Method for sequencing polynucleotides.
  • Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of determining an ordered sequence of subfragments of a nucleic acid fragment by hybridization of oligonucleotide.
  • Williams, Peter; Taylor, Thomas J.; Williams, Daniel J. B.; Gould, Ian; Hayes, Mark A., Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  • Williams, Peter; Taylor, Thomas J.; Williams, Daniel J. B.; Gould, Ian; Hayes, Mark A., Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  • Williams,Peter; Hayes,Mark A.; Rose,Seth D.; Bloom,Linda B.; Reha Krantz,Linda J.; Pizziconi,Vincent B., Method of determining the nucleotide sequence of oligonucleotides and DNA molecules.
  • Brown James F. ; Silver Jonathan E. ; Kalinina Olga V.,CAX, Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly.
  • Nyren P.ang.l,SEX ; Uhlen Mathias,SEX ; Ronaghi Mostafa,SEX, Method of sequencing DNA.
  • Nyren Pal,SEX, Method of sequencing DNA based on the detection of the release of pyrophosphate and enzymatic nucleotide degradation.
  • Wickramasinghe Hemantha K. (Chappaqua NY) Zenhausern Frederic (Mohegan Lake NY), Method suitable for identifying a code sequence of a biomolecule.
  • Swartz Harold M. ; Goda Fuminori ; Walczak Tadeusz ; Liu Ke Jian, Methodology for determining oxygen in biological systems.
  • Ulmer Kevin M. (Cohasset MA), Methods and apparatus for DNA sequencing.
  • Quake, Stephen; Unger, Marc, Methods and apparatus for analyzing polynucleotide sequences.
  • Quake, Stephen; Volkmuth, Wayne; Unger, Marc, Methods and apparatus for analyzing polynucleotide sequences.
  • Quake,Stephen; Braslavsky,Ido; Hebert,Benedict; Kartalov,Emil, Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension.
  • Chan, Eugene Y.; Gleich, Lance C.; Wellman, Parris S., Methods and apparatus for characterization of single polymers.
  • Quake,Stephen R., Methods and apparatuses for analyzing polynucleotide sequences.
  • Quake,Stephen; Kartalov,Emil Paskalev, Methods and apparatuses for analyzing polynucleotide sequences.
  • Chan, Eugene Y.; Gleich, Lance C.; Wellman, Parris S., Methods and apparatuses for characterization of single polymers.
  • Chan, Eugene Y.; Gleich, Lance C.; Wellman, Parris S., Methods and apparatuses for stretching polymers.
  • Brennan Thomas M. (2000 Broadway ; No. 705 San Francisco CA 94115) Heyneker Herbert L. (360 Forest Ave. ; No. 506 Palo Alto CA 94301), Methods and compositions for determining the sequence of nucleic acids.
  • Ness Jeffrey Van ; Tabone John C. ; Howbert J. Jeffry ; Mulligan John T., Methods and compositions for enhancing sensitivity in the analysis of biological-based assays.
  • Buzby,Philip Richard, Methods and compositions for improving fidelity in a nucleic acid synthesis reaction.
  • Buzby, Philip Richard, Methods and compositions for sequencing a nucleic acid.
  • Harris, Timothy; Buzby, Philip Richard; Jarosz, Mirna; DiMeo, James Joseph; Gill, Jaime, Methods and devices for nucleic acid sequence determination.
  • Eugene Y. Chan, Methods and products for analyzing polymers.
  • Cheng Suzanne (El Cerrito CA), Methods and reagents for the polymerase chain reaction amplification of long DNA sequences.
  • Heller Michael J. ; Tu Eugene ; Sosnowski Ronald G. ; O'Connell James P., Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis.
  • Harris,Timothy D., Methods for increasing accuracy of nucleic acid sequencing.
  • Blakesley Robert W., Methods for preventing inhibition of nucleic acid synthesis by pyrophosphate.
  • Gilmanshin Rudolf ; Chan Eugene Y., Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer.
  • Gilmanshin, Rudolf; Chan, Eugene Y, Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer.
  • Eugene Y. Chan, Methods of analyzing polymers using ordered label strategies.
  • Tsui Lap-Chee,CAX ; Riordan John R.,CAX ; Collins Francis S. ; Rommens Johanna M.,CAX ; Iannuzzi Michael C. ; Kerem Bat-Sheva,CAX ; Drumm Mitchell L. ; Buchwald Manuel,CAX, Methods of detecting cystic fibrosis gene by nucleic acid hybridization.
  • Harris, Timothy D.; Boyce, IV, John J., Methods of equalizing representation levels of nucleic acid targets.
  • Cantor Charles R. (Boston MA), Methods of preparing probe array by hybridation.
  • Beattie Kenneth L., Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions.
  • Soper Steven A. ; Davies Jack D. ; Vladimirsky Yuli, Microsystem for rapid DNA sequencing.
  • Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Modified nucleotides and methods of preparing and using same.
  • Chan Eugene Y., Molecular motors.
  • Mathies Richard A. (Contra Costa County CA) Huang Xiaohua C. (Mt. View CA) Quesada Mark A. (San Francisco CA), Multiple tag labeling method for DNA sequencing.
  • Yeung Edward S. (Ames IA) Taylor John A. (Nevada IA), Multiplexed fluorescence detector system for capillary electrophoresis.
  • Wu-Bo Li ; Paul E. Nisson ; Joel Jessee, Normalized nucleic acid libraries and methods of production thereof.
  • Khanna Pyare (Mountain View CA) Ullman Edwin F. (Atherton CA), Novel alkyl substituted fluorescent compounds and polyamino acid conjugates.
  • Nazarenko Irina A. ; Bhatnagar Satish K. ; Winn-Deen Emily S. ; Hohman Robert J., Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon.
  • Carrico Robert J. (Elkhart IN), Nucleic acid hybridization assay employing detectable anti-hybrid antibodies.
  • Densham,Daniel Henry, Nucleic acid sequence analysis.
  • Siddiqi, Suhaib, Nucleotide analogs.
  • Gryaznov Sergei M. (San Mateo CA) Lloyd David H. (Daly City CA), Oligonucleotide clamps having diagnostic applications.
  • Konrad Michael W., Optical detection of position of oligonucleotides on large DNA molecules.
  • Walt David R. ; Michael Karri L ; Chadha Suneet, Optical sensor apparatus for far-field viewing and making optical analytical measurements at remote locations.
  • Austin, Robert H.; Tegenfeldt, Jonas O.; Chan, Eugene Y., Optically characterizing polymers.
  • Hardin Susan Houck ; Homayouni Ramin ; Hardin Paul Eric, Optimized primer library for gene sequencing and method of using same.
  • Shimon Weiss ; Marcel Bruchez, Jr. ; Paul Alivisatos, Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes.
  • Blanco Luis (Madrid) Bernad Antonio (Madrid) Salas Margarita (Madrid ESX), PHI29 DNA polymerase.
  • Harris, Timothy D., Paired-end reads in sequencing by synthesis.
  • Mathies Richard ; Glazer Alexander ; Ju Jingyue, Primers labeled with energy transfer coupled dyes for DNA sequencing.
  • Pease R. Fabian (Stanford CA) McGall Glenn (Mountain View CA) Goldberg Martin J. (San Jose CA) Rava Richard P. (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Goss Virginia (Santa Barbara CA) Strye, Printing molecular library arrays using deprotection agents solely in the vapor phase.
  • Pease R. Fabian ; McGall Glenn ; Goldberg Martin J. ; Rava Richard P. ; Fodor Stephen P. A. ; Goss Virginia ; Stryer Lubert ; Winkler James L., Printing oligonucleotide arrays using deprotection agents solely in the vapor phase.
  • Grossman Paul David (Burlingame CA) Fung Steven (Palo Alto CA) Menchen Steven Michael (Fremont CA) Woo Sam Lee (Redwood City CA) Winn-Deen Emily Susan (Foster City CA), Probe composition containing a binding domain and polymer chain and methods of use.
  • Mathies Richard ; Glazer Alexander ; Ju Jingyue, Probes labeled with energy transfer couples dyes exemplified with DNA fragment analysis.
  • Mathies Richard A. (El Cerrito CA) Glazer Alexander (Orinda CA) Ju Jingyue (Berkeley CA), Probes labelled with energy transfer coupled dyes.
  • Mullis Kary B. (Kensington CA), Process for amplifying nucleic acid sequences.
  • Mullis Kary B. (La Jolla CA) Erlich Henry A. (Oakland CA) Arnheim Norman (Woodland Hills CA) Horn Glenn T. (Emeryville CA) Saiki Randall K. (Richmond CA) Scharf Stephen J. (Berkeley CA), Process for amplifying, detecting, and/or cloning nucleic acid sequences.
  • Mullis Kary B. (La Jolla CA) Erlich Henry A. (Oakland CA) Gelfand David H. (Oakland CA) Horn Glenn (Emeryville CA) Saiki Randall K. (Richmond CA), Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme.
  • Mullis Kary B. (Kensington CA) Erlich Henry A. (Oakland CA) Arnheim Norman (Woodland Hills CA) Horn Glenn T. (Emeryville CA) Saiki Randall K. (Richmond CA) Scharf Stephen J. (Berkeley CA), Process for amplifying, detecting, and/or-cloning nucleic acid sequences.
  • Gelfand David H. (Oakland CA) Stoffel Susanne (El Cerrito CA) Lawyer Frances C. (Oakland CA) Saiki Randall K. (Richmond CA), Purified thermostable enzyme.
  • Hyman Edward (Apt. 8C. ; 1000 Windsor Shore Dr. Columbia SC 29223), Pyrophosphate-based method and apparatus for sequencing nucleic acids.
  • Khankari Rajendra K. ; Hontz John ; Chastain Sara J. ; Katzner Leo, Rapidly dissolving robust dosage form.
  • Furuichi Yasuhiro (Kamakura JPX) Richardson Michael A. (Yokohama JPX), Recombinant sigma NS protein.
  • George M. Church ; Rob Mitra, Replica amplification of nucleic acid arrays.
  • Cantu Gary R. (San Jose CA) Rimsa Joseph R. (Milpitas CA) Van Gelder Ezra (Palo Alto CA) Steinberg Daniel B. (Campbell CA) Hueton Iain H. (Ogden UT), Rotating scanner system for reading multiple storage layer radiation screens.
  • Parce,J. Wallace; Nikiforov,Theo T.; Mehta,Tammy Burd; Kopf Sill,Anne R.; Chow,Andrea W.; Knapp,Michael R., Sequencing by incorporation.
  • Middendorf Lyle R. (Lincoln NE) Patonay Gabor (Stone Mountain GA), Sequencing near infrared and infrared fluorescence labeled DNA for detecting useing laser diodes.
  • Middendorf Lyle R. (Lincoln NE) Patonay Gabor (Stone Mountain GA), Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes.
  • Patonay Gabor ; Narayanan Narasimhachari ; Strekowski Lucjan ; Middendorf Lyle Richard ; Lipowska Malgorzata, Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes and suitable labels the.
  • Patonay Gabor ; Narayanan Narasimhachari ; Brumbaugh John A. ; Middendorf Lyle Richard, Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes and suitable labels therefor.
  • Patonay Gabor (Stone Mountain GA) Narayanan Narasimhachari (Lincoln NE) Strekowski Lucjan (Stone Mountain GA) Middendorf Lyle R. (Lincoln NE) Lipowska Malgorzata (Decatur GA), Sequencing near infrared and infrared fluorescense labeled DNA for detecting using laser diodes and suitable labels ther.
  • Dower William J. (Menlo Park CA) Fodor Stephen P. A. (Palo Alto CA), Sequencing of surface immobilized polymers utilizing microflourescence detection.
  • Dower,William J.; Fodor,Stephen P. A., Sequencing of surface immobilized polymers utilizing microflourescence detection.
  • Lapidus,Stanley N; Buzby,Philip Richard; Harris,Timothy, Short cycle methods for sequencing polynucleotides.
  • Lapidus,Stanley; Buzby,Phillip Richard; Harris,Timothy, Short cycle methods for sequencing polynucleotides.
  • Ansorge Wilhelm,DEX ; Voss Hartmut,DEX ; Stegemann Josef,DEX ; Wiemann Stefan,DEX, Simultaneous sequencing of nucleic acids.
  • Lapidus, Stanley, Single molecule sequencing of captured nucleic acids.
  • Shera E. Brooks (Los Alamos NM), Single molecule tracking.
  • Innis Michael A. (Moraga CA), Structure-independent DNA amplification by the polymerase chain reaction.
  • Mao Fei ; Leung Wai-Yee ; Haugland Richard P., Sulfonated xanthene derivatives.
  • Fodor Stephen P. A. (Palo Alto CA) Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Stryer Lubert (Stanford CA), Synthesis and screening of immobilized oligonucleotide arrays.
  • Goodman Myron F. ; Reha-Krantz Linda J.,CAX, Synthesis of fluorophore-labeled DNA.
  • Williams John G. K., System and methods for nucleic acid sequencing of single molecules by polymerase synthesis.
  • Smith Lloyd M. ; Hood Leroy E. ; Hunkapiller Michael W. ; Hunkapiller Tim J. ; Connell Charles R., Tagged extendable primers and extension products.
  • Chernajovsky Yuti Luis Alberto,GB2, Translational enhancer DNA.
  • Spindt Christopher J. (Menlo Park CA) Macaulay John M. (Palo Alto CA) Duboc ; Jr. Robert M. (Menlo Park CA) Searson Peter C. (Baltimore MD), Use of charged-particle tracks in fabricating gated electron-emitting devices.
  • Legras Roger (Hannut BEX) Jongen Yves (Ohain BEX), method of producing perforations in a solid material in sheet form, an irradiation device for working the method, and th.
  • 이 특허를 인용한 특허 (22)

    1. Rothberg, Jonathan M.; Kabiri, Ali; Sickler, Jason W.; Gyarfas, Brett J.; Lackey, Jeremy; Schmid, Gerard, Active-source-pixel, integrated device for rapid analysis of biological and chemical specimens.
    2. Harris, John L.; West, Adrian Mark Thomas; Ten Broeck, Dirk Peter; Protozanova, Ekaterina, Device for preparing a sample.
    3. Meltzer, Robert H.; Griffis, Joshua W., Device for stretching a polymer in a fluid sample.
    4. Rothberg, Jonathan M.; Fife, Keith G.; Boisvert, David, Integrated device for temporal binning of received photons.
    5. Rothberg, Jonathan M.; Kabiri, Ali; Sickler, Jason W.; Gyarfas, Brett J.; Lackey, Jeremy; Schmid, Gerard; Cipriany, Benjamin; Jewell, Jack; West, Lawrence; Ferrigno, Michael; Glenn, Paul E.; Bellofiore, Anthony, Integrated device with external light source for probing detecting and analyzing molecules.
    6. Rothberg, Jonathan M.; Kabiri, Ali; Sickler, Jason W.; Gyarfas, Brett J.; Lackey, Jeremy; Schmid, Gerard; West, Lawrence C.; Fife, Keith G.; Cipriany, Benjamin; Ghasemi, Farshid, Integrated device with external light source for probing detecting and analyzing molecules.
    7. Meltzer, Robert H.; Griffis, Joshua W., Intercalation methods and devices.
    8. Noyel, Guillaume, Method of monitoring the appearance of the surface of a tire.
    9. Xiao, Ming; Cao, Han, Methods and devices for single-molecule whole genome analysis.
    10. Travers, Kevin; Otto, Geoff; Turner, Stephen; Heiner, Cheryl; Ma, Congcong, Methods and systems for obtaining a single molecule consensus sequence.
    11. Travers, Kevin; Otto, Geoff; Turner, Stephen; Heiner, Cheryl; Ma, Congcong, Methods for obtaining a single molecule consensus sequence.
    12. Cao, Han; Deshpande, Parikshit A.; Austin, Michael D.; Boyce-Jacino, Michael, Methods of macromolecular analysis using nanochannel arrays.
    13. Cao, Han; Deshpande, Parikshit A; Austin, Michael D; Boyce-Jacino, Michael, Methods of macromolecular analysis using nanochannel arrays.
    14. Cao, Han; Deshpande, Parikshit A.; Austin, Michael D.; Boyce-Jacino, Michael, Nanonozzle device arrays: their preparation and use for macromolecular analysis.
    15. Cao, Han; Deshpande, Parikshit A.; Austin, Michael David; Boyce-Jacino, Michael, Nanonozzle device arrays: their preparation and use for macromolecular analysis.
    16. Turner, Stephen; Sorenson, Jon; Maxham, Kenneth Mark; Eid, John; Heiner, Cheryl; Travers, Kevin, Nucleic acid sequence analysis.
    17. Rothberg, Jonathan M.; Kabiri, Ali; Sickler, Jason W.; Gyarfas, Brett J.; Lackey, Jeremy; Schmid, Gerard; Cipriany, Benjamin; Jewell, Jack; West, Lawrence; Ferrigno, Michael; Glenn, Paul E.; Cohen, Adam E.; Bellofiore, Anthony, Optical system and assay chip for probing, detecting and analyzing molecules.
    18. Rothberg, Jonathan M.; Kabiri, Ali; Sickler, Jason W.; Gyarfas, Brett J.; Lackey, Jeremy; Schmid, Gerard; Glenn, Paul E.; West, Lawrence C.; Cipriany, Benjamin; Fife, Keith G., Optical system and assay chip for probing, detecting and analyzing molecules.
    19. Xiao, Ming; Cao, Han; Deshpande, Parikshit A.; Boyce-Jacino, Michael, Polynucleotide mapping and sequencing.
    20. Xiao, Ming; Cao, Han; Deshpande, Parikshit A.; Boyce-Jacino, Michael, Polynucleotide mapping and sequencing.
    21. Patil, Vishal; Mollova, Emilia; Gilmanshin, Rudolf, Reaction chamber.
    22. Travers, Kevin; Otto, Geoff; Turner, Stephen; Heiner, Cheryl; Ma, Congcong, Sequencing using concatemers of copies of sense and antisense strands.

    문의처: helpdesk@kisti.re.kr전화: 080-969-4114

    AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

    AI-Helper 아이콘
    AI-Helper
    안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
    ※ AI-Helper는 부적절한 답변을 할 수 있습니다.

    선택된 텍스트

    맨위로