IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0452299
(2008-06-07)
|
등록번호 |
US-8213013
(2012-07-03)
|
우선권정보 |
DE-10 2007 031 284 (2007-07-05) |
국제출원번호 |
PCT/EP2008/004556
(2008-06-07)
|
§371/§102 date |
20091223
(20091223)
|
국제공개번호 |
WO2009/015723
(2009-02-05)
|
발명자
/ 주소 |
- Zirk, Kai-Uwe
- Freitag, Hans-Joachim
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
0 인용 특허 :
2 |
초록
▼
The invention relates to a sensor for determining a concentration of a substance contained in a fluid-containing matrix, with a measurement chamber (5), a sender (3) for the emission of optical radiation (6) into the measurement chamber, and a receiver (4) for receiving optical radiation which has t
The invention relates to a sensor for determining a concentration of a substance contained in a fluid-containing matrix, with a measurement chamber (5), a sender (3) for the emission of optical radiation (6) into the measurement chamber, and a receiver (4) for receiving optical radiation which has traversed the measurement chamber, wherein the measurement chamber is designed for bringing into the matrix and is filled with a specific fluid, and the wall (12, 13) is at least sectionally permeable to the diffusion of the substance. A control and evaluation circuit (7) is connected to the sender (3) and controls the sender (3), and is connected to the receiver (4) for selecting the receiver signals and determines, from the receiver signal, a measurement for the concentration of the substance in the matrix.
대표청구항
▼
1. A sensor for determining a concentration of a first substance found in a matrix, the matrix being a fluid matrix or a fluid-containing matrix, the sensor having: a measurement chamber,a transmitter for issuing optical radiation into the measurement chamber,a receiver for receiving optical radiati
1. A sensor for determining a concentration of a first substance found in a matrix, the matrix being a fluid matrix or a fluid-containing matrix, the sensor having: a measurement chamber,a transmitter for issuing optical radiation into the measurement chamber,a receiver for receiving optical radiation after the optical radiation has passed through the measurement chamber, anda control and evaluation circuit connected with the transmitter to turn the transmitter on, and connected with the receiver to read out a signal from the receiver,wherein the transmitter and the receiver are part of a wall of the measurement chamber, so that a unit formed in this manner is configured for introduction into the matrix,wherein the measurement chamber is filled with a measurement medium,wherein the wall of the measurement chamber is better diffusion-permeable for the first substance, at least in certain sections, than for remaining substances of the matrix, in order to balance out concentration differences of the first substance between the measurement medium and the matrix, and thus to separate the first substance from the remaining substances of the matrix, andwherein the control and evaluation circuit determines the concentration of the first substance in the matrix from the signal from the receiver. 2. The sensor according to claim 1, wherein the measurement chamber is formed by an oblong housing, wherein the transmitter is affixed on a first face side of the oblong housing, andwherein the receiver is affixed on a second face side of the oblong housing, the second face side being opposite from the first face side. 3. The sensor according to claim 2, wherein the oblong housing is tubular and has a diameter of less than 3 mm. 4. The sensor according to claim 2, wherein the transmitter and the receiver are glued to the first and second face sides of the oblong housing, respectively, to be tightly fixed in place. 5. The sensor according to claim 2, further comprising conductor tracks on an outside of the oblong housing, wherein, by way of the conductor tracks, the control and evaluation circuit is connected with at least one of the transmitter and the receiver. 6. The sensor according to claim 2, wherein the oblong housing has at least two grooves running between the first and second face sides, wherein a first conductor track is introduced into a first groove of the at least two grooves, andwherein a second conductor track is introduced into a second groove of the at least two grooves. 7. The sensor according to claim 2, wherein the oblong housing is configured as an insertion puncture sensor such that the oblong housing has a tip at one end of the oblong housing. 8. The sensor according to claim 1, wherein the transmitter has a radiation source and at least one of an imaging system and an optical filter system. 9. The sensor according to claim 8, wherein the radiation source comprises a light-emitting diode, laser diode, or light-emitting diode array. 10. The sensor according to claim 8, wherein the transmitter has an imaging system comprising collimator optics. 11. The sensor according to claim 8, wherein the transmitter has an optical filter system comprising at least one member selected from the group consisting of a polarization filter, an interference filter, and an edge filter. 12. The sensor according to claim 8, wherein the control and evaluation circuit determines at least one of a polarization rotation and an intensity change of the radiation as the radiation passes through the measurement chamber filled with the measurement medium, the control and evaluation circuit deriving the concentration of the first substance via the determination. 13. The sensor according to claim 1, wherein the receiver has two photosensitive elements and at least one optical filter system. 14. The sensor according to claim 1, wherein the measurement medium is a physiological saline solution or glucose solution, and wherein the matrix is a biological tissue. 15. The sensor according to claim 1, wherein the wall brings about at least one of a size selection and a shape selection, so that better diffusion permeability for substances having a certain size or molecular shape exists. 16. The sensor according to claim 1, wherein the wall has a porous material comprising ceramic, silicon, plastic, glass, or metal, at least in diffusion-permeable sections, wherein the porous material is provided with a coating on at least one of an inside of the porous material and an outside of the porous material, andwherein the coating imparts specific diffusion properties for the first substance relative to the wall. 17. The sensor according to claim 1, further comprising: a sealed chamber having at least one partition wall delimiting the sealed chamber from the measurement chamber,a sealed-chamber transmitter on the at least one partition wall, anda sealed-chamber receiver on the at least one partition wallwherein at least one of the transmitter and the sealed-chamber transmitter can issue optical radiation into the sealed chamber,wherein at least one of the receiver and the sealed-chamber receiver can receive optical radiation after the optical radiation has passed through the sealed chamber,wherein the wall of the measurement chamber is diffusion-permeable for at least two substances, andwherein the at least one partition wall is diffusion-permeable for only part of the at least two substances. 18. A production method for producing a sensor, the production method comprising steps of: providing a unit comprising: a measurement chamber formed by an oblong housing, being filled with a measurement medium, and having a wall;a transmitter for issuing optical radiation into the measurement chamber; anda receiver for receiving optical radiation after the optical radiation has passed through the measurement chamber;wherein the transmitter and the receiver are part of the wall of the measurement chamber so that the unit is configured for introduction into a matrix, the matrix being a fluid matrix or a fluid-containing matrix;wherein the measurement chamber is formed by an oblong housing composed of porous material comprising ceramic, silicon, plastic, glass, or metal;wherein the wall of the measurement chamber is better diffusion-permeable for a first substance of the matrix, at least in certain sections, than for remaining substances of the matrix, in order to balance out concentration differences of the first substance between the measurement medium and the matrix, and thus to separate the first substance from the remaining substances of the matrix;providing a control and evaluation circuit connected to the transmitter to turn the transmitter on and connected to the receiver to read out a signal from the receiver, the control and evaluation circuit determining the concentration of the first substance in the matrix from a receiver signal; andapplying a coating on at least one of an inside and an outside of the porous material, the coating imparting specific diffusion properties for the first substance relative to the wall. 19. The production method according to claim 18, wherein the coating is applied using a sol-gel method, a vapor deposition method, or a deposition method. 20. The production method according to claim 18, wherein the oblong housing has a first face side, a second face opposite the first face side, and two grooves connecting the first and second face sides on an outside of the oblong housing, and wherein conductor strips are formed in the two grooves using thick-layer technology. 21. The production method according to claim 18, wherein the oblong housing has a first face side and a second face side opposite to the first face side, wherein the transmitter and the receiver are attached to the oblong housing on the first and second face sides, respectively, andwherein the measurement chamber is filled with measurement medium in that the unit is placed into an evacuated chamber and the measurement medium is let into the evacuated chamber.
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