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다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0904901 (2010-10-14) |
등록번호 | US-8216530 (2012-07-10) |
발명자 / 주소 |
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 | 피인용 횟수 : 3 인용 특허 : 568 |
A reagent tube configured with a stellated shaped pattern, on its bottom interior surface, configured to facilitate complete or near-complete withdrawal of fluid from the tube, via a pipette tip. The reagent tube may be used for transporting reagents and for carrying out processing operations on bio
A reagent tube configured with a stellated shaped pattern, on its bottom interior surface, configured to facilitate complete or near-complete withdrawal of fluid from the tube, via a pipette tip. The reagent tube may be used for transporting reagents and for carrying out processing operations on biological samples with the reagents, such as preparing polynucleotides extracted from the sample for amplification.
1. A reagent tube for insertion into a tube holder strip, comprising: a tube body having a top, a bottom, and an interior surface, wherein the top, bottom, and interior surface of the tube body define a volume configured to hold a liquid;a radially-extending lip at the top of the tube body configure
1. A reagent tube for insertion into a tube holder strip, comprising: a tube body having a top, a bottom, and an interior surface, wherein the top, bottom, and interior surface of the tube body define a volume configured to hold a liquid;a radially-extending lip at the top of the tube body configured for locking engagement with cooperating structure on a tube holder strip to retain the tube after insertion into a tube holder strip;a pattern of convex ridges extending radially and centered at the bottom of the interior surface of the tube, wherein the convex ridges extend vertically from the bottom interior surface of the tube body, wherein the pattern of ridges and the ridges are configured to enable pipetting of substantially all of the liquid held in the reagent tube; anda ring centered at the bottom of the interior surface of the tube, wherein the pattern of radially extending convex ridges intersect the ring. 2. The tube of claim 1, wherein the number of ridges is selected from 3, 4, 5, 6, 8, 9, 10, or 12. 3. The tube of claim 1, wherein the ridges do not meet one another at a center of the pattern. 4. The tube of claim 1, wherein each of the ridges has a width, wherein the width tapers from a widest point to an apex. 5. The tube of claim 4, wherein the widest point has a width of 50 microns. 6. The tube of claim 1, wherein each of the ridges has a height, wherein the height tapers from a highest point to an apex. 7. The tube of claim 1, wherein each of the ridges has a length, measured as the shortest distance from its widest point to its apex. 8. The tube of claim 6, wherein the length is 0.5 mm. 9. The tube of claim 1, having a volume of 0.3 ml. 10. The tube of claim 1, having a volume of between 0.1 ml to 0.65 ml. 11. The reagent tube of claim 1, where the top of the reagent tube has chamfer edges to reduce expansion of the top rim of the tube during heat sealing of a foil on the top of the tube. 12. The reagent tube of claim 1, further comprising a reagent contained therein, and wherein the tube is sealed on top by a foil. 13. The reagent tube of claim 12, further comprising an identifiable code on the top. 14. The reagent tube of claim 12, wherein the reagent is in liquid or lyophilized form. 15. The tube of claim 1, wherein the pattern of ridges extending radially and centered at the bottom of the interior surface of the tube is a stellated pattern. 16. The tube of claim 15, wherein each of the ridges has a width, wherein the width tapers from a widest point to an apex. 17. The tube of claim 15, wherein each of the ridges has a height, wherein the height tapers from a widest point to an apex. 18. The tube of claim 15, wherein the stellated pattern has a rotation axis of symmetry, the axis disposed perpendicular to the bottom of the tube, and wherein the ridges are disposed symmetrically about the rotation axis. 19. The tube of claim 15, wherein the stellated pattern additionally comprises a circular cutout at the center of the bottom of the tube. 20. The reagent tube of claim 15, wherein the stellated pattern is designed to enable liquid to be pipetted out of the tube, with less than 1 microliter of residual volume. 21. The tube of claim 16, wherein the widest point is closest to a center of the stellated pattern. 22. The tube of claim 17, wherein the highest point is closest to a center of the stellated pattern. 23. The tube of claim 22, wherein the highest point has a height of 25-30 microns. 24. A reagent holding system, comprising: a reagent tube, comprising: a tube body having a top, a bottom, and an interior surface, wherein the top, bottom, and interior surface of the tube body define a volume configured to hold a liquid;a radially-extending lip at the top of the tube body;a pattern of convex ridges extending radially and centered at the bottom of the interior surface of the tube, wherein the convex ridges extend vertically from the bottom interior surface of the tube body, wherein the pattern of ridges and the ridges are configured to enable pipetting of substantially all of the liquid held in the reagent tube; anda ring centered at the bottom of the interior surface of the tube, wherein the pattern of radially extending convex ridges intersect the ring; anda tube-holding strip having an opening for receiving the reagent tube with a cooperating structure configured for locking engagement with the lip of the tube body after insertion of the tube body into the tube holder strip. 25. The reagent holding system of claim 24, wherein the ridges do not meet one another at a center of the pattern. 26. The reagent holding system of claim 24, wherein the top of the reagent tube has chamfer edges to reduce expansion of the top rim of the tube during heat sealing of a foil on the top of the tube. 27. The reagent holding system of claim 24, wherein the cooperating structure comprises a snap tab. 28. A reagent tube for insertion into a tube holder strip, comprising: a tube body having a top, a bottom, and an interior surface, wherein the top, bottom, and interior surface of the tube body define a volume configured to hold a liquid;a radially-extending lip configured for locking engagement with cooperating structure on a tube holder strip to retain the tube after insertion into the tube holder strip, the lip comprising a top surface proximal to the top of the tube body, a bottom surface opposite the top surface, a radial wall extending between the top and bottom surface of the lip, and a beveled edge located at the junction of the top surface and the radial wall;a pattern of convex ridges extending radially and centered at the bottom of the interior surface of the tube, wherein the convex ridges extend vertically from the bottom interior surface of the tube body, wherein the pattern of ridges and the ridges are configured to enable pipetting of substantially all of the liquid held in the reagent tube; anda ring centered at the bottom of the interior surface of the tube, wherein the pattern of radially extending convex ridges intersect the ring. 29. The tube of claim 27, wherein the ridges do not meet one another at a center of the pattern. 30. The reagent tube of claim 27, where the top of the reagent tube has chamfer edges to reduce expansion of the top rim of the tube during heat sealing of a foil on the top of the tube. 31. The reagent tube of claim 27, wherein the width of the radial lip is at least twice as large as the thickness of the radial lip.
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