Clay-based hemostatic agents and devices for the delivery thereof
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61L-015/14
A61K-009/14
A61F-013/00
A61F-013/37
A61L-015/16
A61L-015/18
출원번호
US-0115699
(2011-05-25)
등록번호
US-8257732
(2012-09-04)
발명자
/ 주소
Huey, Raymond J.
Lo, Denny
Burns, Daniel J.
Basadonna, Giacomo
Hursey, Francis X.
출원인 / 주소
Z-Medica Corporation
대리인 / 주소
Knobbe Martens Olson & Bear LLP
인용정보
피인용 횟수 :
20인용 특허 :
78
초록▼
A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Anothe
A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.
대표청구항▼
1. A device for promoting the clotting of blood, comprising: a dry gauze;a clay material disposed on the gauze;a binder, comprising a material that is distinct from the gauze and the clay, that adheres at least a portion of the clay material to a surface of the gauze so that the device is substantia
1. A device for promoting the clotting of blood, comprising: a dry gauze;a clay material disposed on the gauze;a binder, comprising a material that is distinct from the gauze and the clay, that adheres at least a portion of the clay material to a surface of the gauze so that the device is substantially free of loose clay;wherein the device is substantially dry; andwherein, when the device contacts a bleeding wound, the clay material is configured to directly contact blood. 2. The device of claim 1, wherein the clay comprises kaolin. 3. The device of claim 1, wherein the binder comprises chitosan, polyvinyl alcohol, guar gum, gelatinized starches, polysaccharides, cellulose, carboxymethylcellulose, or calcium alginate. 4. The device of claim 1, wherein the gauze is nonwoven. 5. The device of claim 1, wherein the gauze comprises polyester. 6. The device of claim 1, wherein the gauze comprises rayon. 7. The device of claim 6, wherein the gauze comprises polyester. 8. The device of claim 2, wherein at least one of an analgesic and an anti-inflammatory agent is mixed with, associated with, or incorporated into the kaolin. 9. The device of claim 8, wherein an analgesic is mixed with, associated with, or incorporated into the kaolin. 10. The device of claim 2, wherein at least one of an antibiotic, an antifungal agent, an anti-microbial agent, a silver ions, and copper ions is mixed with, associated with, or incorporated into the kaolin. 11. The device of claim 1, further comprising the clay material impregnated into the gauze. 12. The device of claim 1, wherein kaolin is present in the device at a weight that is at least about 44% of the total weight of the gauze and the kaolin in the device. 13. The device of claim 1, wherein the device is configured to substantially absorb blood. 14. A device for promoting the clotting of blood, comprising: a gauze that is in a state such that it is not saturated with a liquid, and is configured so as to be capable of absorbing a substantial amount of blood;a clay material disposed on the gauze;a binder, comprising a material that is distinct from the gauze and the clay, that adheres at least a portion of the clay material to a surface of the gauze so that the device is substantially free of loose clay;wherein the clay material is positioned on the device in a region configured to contact blood when the device is placed on a bleeding wound. 15. The device of claim 14, wherein the clay comprises kaolin. 16. The device of claim 14, wherein the binder comprises chitosan, polyvinyl alcohol, guar gum, gelatinized starches, polysaccharides, cellulose, carboxymethylcellulose, or calcium alginate. 17. The device of claim 14, wherein the gauze is nonwoven. 18. The device of claim 14, wherein the gauze comprises polyester. 19. The device of claim 18, wherein the gauze comprises rayon. 20. A method of promoting the clotting of blood, comprising administering the device of claim 14 to a person suffering from a wound with a sufficient amount of bleeding so as to have substantial need for use of a such a device.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (78)
McCabe John Patrick,GBX ; Stevens Peter John,GBX, Absorbent product.
Kaessmann Hans-Jurgen (Hamburg DEX) An Haak Karl W. (Am Hedreisch 25 D-44225 Dortmund DEX), Chitosan foil for wound sealing and process for its preparation.
Huey, Raymond J.; Lo, Denny; Burns, Daniel J.; Basadonna, Giacomo; Hursey, Francis X., Clay-based hemostatic agents and devices for the delivery thereof.
Huey, Raymond J.; Lo, Denny; Burns, Daniel J.; Basadonna, Giacomo; Hursey, Francis X., Clay-based hemostatic agents and devices for the delivery thereof.
Errede Louis A. (North Oaks MN) Stoesz James D. (St. Paul MN) Winter ; deceased George D. (late of St. Paul MN by Jenny Upton ; personal representative), Composite wound dressing.
Xu,Teng; Vaughn,Stephen Neil; Hall,Richard B.; Clem,Kenneth Ray; Johnson,Jack W., Low metal content catalyst compositions and processes for making and using same.
Myers Gene (2727 S. Tamiami Trail ; Suite 2A Sarasota FL 34239) Coury William S. (2830 Bay Shore Cir. Sarasota FL 34234), Method and apparatus for arteriotomy closure.
Farris Diane Dunn ; Hall Alicia Mary ; Osborn ; III Thomas Ward, Method for opening a packaging device and retrieving an interlabial absorbent article placed therein.
Scherson Daniel A. (2568 Saybrook Rd. University Hts. OH 44118) Burk Melvyn I. (21001 Halburton Rd. Beachwood OH 44122), Oxygen producing bandage and method.
Errede Louis A. (North Oaks MN) Stoesz James D. (St. Paul MN) Upton Jenny (Bridgend GB7), Water-swellable composite sheet of microfibers of PTFE and hydrophilic absorptive particles.
Huey, Raymond J.; Lo, Denny; Burns, Daniel J.; Basadonna, Giacomo; Hursey, Francis X., Clay-based hemostatic agents and devices for the delivery thereof.
Huey, Raymond J.; Lo, Denny; Burns, Daniel J.; Basadonna, Giacomo; Hursey, Francis X., Clay-based hemostatic agents and devices for the delivery thereof.
Huey, Raymond J.; Lo, Denny; Burns, Daniel J.; Basadonna, Giacomo; Hursey, Francis X., Clay-based hemostatic agents and devices for the delivery thereof.
Huey, Raymond J.; Lo, Denny; Burns, Daniel J.; Basadonna, Giacomo; Hursey, Francis X., Clay-based hemostatic agents and devices for the delivery thereof.
Diegelmann, Robert F.; Ward, Kevin R.; Carr, Marcus E.; Bowlin, Gary Lee, Hemostasis of wound having high pressure blood flow using kaolin and bentonite.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.