IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0233717
(2011-09-15)
|
등록번호 |
US-8258324
(2012-09-04)
|
발명자
/ 주소 |
- McManus, Samuel P.
- Kozlowski, Antoni
- Hutchison, Tracy L.
- Bray, Brian
- Shen, Xiaoming
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
2 인용 특허 :
28 |
초록
▼
Methods for forming maleimide functionalized polymers are provided. In one such embodiment, a maleimide functionalized polymer is prepared in a method that includes a step of carrying out a reverse Diels-Alder reaction. Intermediates useful in the methods, as well as methods for preparing the interm
Methods for forming maleimide functionalized polymers are provided. In one such embodiment, a maleimide functionalized polymer is prepared in a method that includes a step of carrying out a reverse Diels-Alder reaction. Intermediates useful in the methods, as well as methods for preparing the intermediates, are also provided. Also provided are polymeric reagents, methods of using polymeric reagents, compounds and conjugates.
대표청구항
▼
1. A compound of the following structure: wherein:X is selected from the group consisting of alkylene, substituted alkylene, alkenylene, substituted alkenylene, —C(O)—, heteroatom and substituted heteroatom;each of R1, R2, R3 and R4 is independently selected from the group consisting of H, halo, hyd
1. A compound of the following structure: wherein:X is selected from the group consisting of alkylene, substituted alkylene, alkenylene, substituted alkenylene, —C(O)—, heteroatom and substituted heteroatom;each of R1, R2, R3 and R4 is independently selected from the group consisting of H, halo, hydroxyl, carboxyl, carboxylalkyl, thiol, alkylthio, acyl, acyloxy, nitro, cyano, azido, trihalomethyl, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkoxy, aryl, substituted aryl, heterocycle, substituted heterocycle, heteroaryl, and substituted heteroaryl; andn′ is 2 to about 10. 2. The compound of claim 1, wherein X is a heteroatom. 3. The compound of claim 2, wherein the heteroatom is O. 4. The compound of claim 1, wherein each of R1, R2, R3 and R4 is H. 5. The compound of claim 1, wherein n′ is 2. 6. The compound of claim 1, wherein X is O, each of R1, R2, R3 and R4 is H, and n′ is 2.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.