High alcohol content foaming compositions with silicone-based surfactants
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A01N-025/00
A61K-031/74
A61K-051/00
A61M-036/14
출원번호
US-0591243
(2006-03-07)
등록번호
US-8263098
(2012-09-11)
국제출원번호
PCT/CA2006/000320
(2006-03-07)
§371/§102 date
20060831
(20060831)
국제공개번호
WO2006/094387
(2006-09-14)
발명자
/ 주소
Fernandez de Castro, Maria Teresa
Koivisto, Bruce Michael
Munoz, Francisco
출원인 / 주소
Deb Worldwide Healthcare Inc.
대리인 / 주소
Neal, Gerber & Eisenberg LLP
인용정보
피인용 횟수 :
1인용 특허 :
223
초록▼
This invention relates to a “high lower alcohol content” (40% v/v of a C1-4 alcohol) liquid composition able to be dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers. The liquid compositions comprise an alcohol, C1-4 (40% v/v), a silicon
This invention relates to a “high lower alcohol content” (40% v/v of a C1-4 alcohol) liquid composition able to be dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers. The liquid compositions comprise an alcohol, C1-4 (40% v/v), a silicone-based surfactant of at least 0.001% by weight to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and mosturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.
대표청구항▼
1. An alcohol disinfecting composition, comprising; a) an alcohol C1-4, or mixtures thereof, present in an amount between about 60% to about 80% v/v of the total composition;b) at least one effective physiologically acceptable silicone-based surface active agent, which includes a lipophilic chain co
1. An alcohol disinfecting composition, comprising; a) an alcohol C1-4, or mixtures thereof, present in an amount between about 60% to about 80% v/v of the total composition;b) at least one effective physiologically acceptable silicone-based surface active agent, which includes a lipophilic chain containing a silicone backbone, for foaming present in an amount from about 0.01% to about 10.0% by weight of the total composition;c) a foam stabilizing agent present in an amount from about 0.01 to about 12.0% by weight of the total composition;d) one or more moisturizers, emollients, lipid layer enhancers, or combinations thereof present in an amount from about 0.05 to about 5.0% by weight of the total composition; ande) water in an amount to balance the total composition to 100% by weight,said alcohol composition optionally including no more than 1% by weight of at least one additional surfactant for adjusting properties of the foam produced from the composition,wherein the composition is mixed with air at low pressure to form a foam. 2. The alcohol disinfecting composition according to claim 1 wherein the silicone-based surfactant is Bis-PEG-20 dimethicone. 3. The alcohol disinfecting composition according to claim 1 wherein the silicone-based surfactant is Bis-PEG-17 dimethicone. 4. The alcohol disinfecting composition according to claim 1 wherein the silicone-based surfactant is Bis-PEG-12 dimethicone. 5. The alcohol disinfecting composition according to claim 1 wherein the silicone-based surfactant is a polyether-modified polysiloxane. 6. The alcohol disinfecting composition according to claim 1 wherein the silicone-based surfactant is a polysiloxane betaine. 7. The composition according to claim 1 wherein the silicone-based surfactant is a mixture of two or more of the silicone-based surfactants selected from the group consisting of Bis-PEG-20 dimethicone, Bis-PEG-17 dimethicone, Bis-PEG-12 dimethicone, 3-(3-hydroxypropyl)-heptamethyltrisiloxaneethoxylated acetate, polyether-modified polysiloxane and polysiloxane betaine. 8. The alcohol disinfecting composition according to claim 1 wherein the foam stabilizing agent is selected from the group consisting of lactic acid esters of monoglycerides,cationic emulsifiers,quaternary ammonium compounds,triquaternized stearic phospholipid complex,hydroxystearamide propyltriamine salts,lactic acid monoglycerides,food emulsifiers selected from the group consisting of glyceryl monostearate, propylene glycol monostearate, and sodium stearoyl lactylate,silicone wax,quaternary ammonium chlorides,an encapsulated oil,microcapsule mineral oil,butyleneglycol, and mixtures thereof. 9. The alcohol disinfecting composition according to claim 1 wherein the foam stabilizing agent is selected from the group consisting of 2-butoxyethanol, glycerine butyleneglycol, cetrimonium chloride, behentrimonium chloride, and combinations thereof. 10. The alcohol disinfecting composition according to claim 1 wherein any one of the moisturizer, emollient and combinations thereof is selected from the group consisting of lanolin,vinyl alcohol,polyvinyl pyrrolidone,polyols selected from the group consisting of glycerol, propylene glycol, butyleneglycol and sorbitol,a fatty alcohol selected from the group consisting of cetyl alcohol, stearyl alcohol, lauryl alcohol, myristyl alcohol and palmityl alcohol,ceteareth 20,an alkylglucoside, and combinations thereof. 11. The alcohol disinfecting composition according to claim 1 wherein the moisturizer or emollient are selected from the group consisting of glyceryl oleate, glycerine, cocoglucoside, PEG-200 hydrogenated glyceryl palmate, or dihydroxypropyl PEG-5 linoleammonium chloride, PEG-7 glyceryl cocoate, and combinations thereof. 12. The alcohol disinfecting composition according to claim 1 further including a preservative in an amount from about 0.01 to about 5% by weight of the total composition. 13. The alcohol disinfecting composition according to claim 1 further comprising an acid or a base to adjust a pH of the disinfecting composition to a pre-selected pH present in an amount from about 0.05 to about 0.5% by weight of the total composition. 14. The alcohol disinfecting composition according to claim 13 wherein the acid is selected from the group consisting of hydrochloric acid, citric acid and phosphoric acid, and the base is sodium sesquicarbonate. 15. The alcohol disinfecting composition according to claim 1 wherein the composition is stored in an unpressurized dispenser having a dispenser pump for mixing the disinfecting composition with air and dispensing foam therefrom. 16. The alcohol disinfecting composition according to claim 1 wherein one or more of the moisturizers, emollients, lipid layer enhancers, or combinations thereof is selected from the group consisting of lanolin,vinyl alcohol,polyvinyl pyrrolidone,polyols selected from the group consisting of glycerol, propylene glycol, butyleneglycol and sorbitol,a fatty alcohol selected from the group consisting of cetyl alcohol, stearyl alcohol, lauryl alcohol, myristyl alcohol and palmityl alcohol,ceteareth 20,an alkylglucoside,mixtures of alkylglucoside and glyceryl oleate,PEG-200 hydrogenated glyceryl palmate,dihydroxypropyl PEG-5 linoleammonium chloride,PEG-7 glyceryl cocoate, and combinations thereof. 17. The alcohol disinfecting composition according to claim 1 further comprising other constituents or materials including organic gums and colloids, lower alkanolamides of higher fatty acids, short chain diols and/or triols, fragrance, coloring matter, ultraviolet absorbers, solvents, emulsifiers, buffers, conditioning agents, antioxidants, bactericides, or medicinal active ingredients. 18. A method of forming a foam using a composition according to claim 1, by storing said composition in a container and having a dispenser pump activating the dispenser pump to mix the alcohol and silicone-based surface active agent mixture with air under low pressure to form a low pressure foam containing alcohol which is dispensed from said dispenser. 19. The composition according to claim 1 wherein the silicone-based surfactant is a Bis-PEG-[10-20] dimethicone. 20. The composition according to claim 19 wherein the foam stabilizing agent is selected from the group consisting of cationic emulsifiers and quaternary ammonium compounds. 21. The composition according to claim 19 wherein the foam stabilizing agent is selected from the group consisting of 2-butoxyethanol, glycerine, butyleneglycol, cetrimonium chloride, and behentrimonium chloride. 22. The composition according to claim 1 wherein the foam stabilizing agent is behentrimonium chloride. 23. The composition according to claim 19 further comprising cocoglucoside and glyceryl oleate. 24. The composition according to claim 22 further comprising PEG-200 hydrogenated glyceryl palmate,PEG-7 glyceryl cocoate, anddihydroxypropyl PEG-5 linoleammonium chloride. 25. The composition according to claim 23 further comprising n-propanol.
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