IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
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출원번호 |
US-0983656
(2011-01-03)
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등록번호 |
US-8267953
(2012-09-18)
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발명자
/ 주소 |
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출원인 / 주소 |
- The Regents of The University of Michigan
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대리인 / 주소 |
Marshall, Gerstein & Borun LLP
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인용정보 |
피인용 횟수 :
1 인용 특허 :
25 |
초록
▼
An angioplasty balloon catheter with an added channel for delivering medication or removing body fluids distal to the site of angioplasty is disclosed. The balloons are especially useful in the treatment of occlusions in saphenous vein grafts, the coronary and carotid arteries, arteries arising from
An angioplasty balloon catheter with an added channel for delivering medication or removing body fluids distal to the site of angioplasty is disclosed. The balloons are especially useful in the treatment of occlusions in saphenous vein grafts, the coronary and carotid arteries, arteries arising from the aorta and branches thereof and in veins flowing to the heart or their tributaries and sub tributaries thereof.
대표청구항
▼
1. A method of applying a therapeutic agent with an angioplasty balloon catheter apparatus, the method comprising: providing an elongate flexible tubular body having a proximal end, a distal end, an outer wall, and an inner wall for insertion into a vessel;defining within the tubular body a therapeu
1. A method of applying a therapeutic agent with an angioplasty balloon catheter apparatus, the method comprising: providing an elongate flexible tubular body having a proximal end, a distal end, an outer wall, and an inner wall for insertion into a vessel;defining within the tubular body a therapeutic lumen defined by the inner wall, the therapeutic lumen having a substantially uniformly circular cross-section from the proximal end to the distal end, the therapeutic lumen having a diameter between about 0.01 inches to about 0.09 inches, the therapeutic lumen having a therapeutic port at the proximal end and a therapeutic mouth at the distal end, the therapeutic port being in fluid communication with the therapeutic lumen and the therapeutic mouth;providing a guidewire lumen adjacent the therapeutic lumen and having a proximal end and a distal opening, the guidewire lumen being adapted to receive a standard-size coronary guidewire therethrough, and positioning the guidewire lumen adjacent to the therapeutic lumen such that the therapeutic lumen and the guidewire lumen near the distal end form essentially a figure eight configuration, wherein the guidewire lumen is provided on the interior of the tubular body, and positioning the guidewire lumen to extend distally from the therapeutic mouth;providing an inflation channel extending through the tubular body and capable of delivering inflation pressure to an angioplasty balloon of the catheter; andcoupling a therapeutic source to the therapeutic port for establishing fluid communication with the therapeutic port for delivering a therapeutic agent to the therapeutic lumen. 2. The method of claim 1, comprising delivering the therapeutic agent before balloon inflation. 3. The method of claim 1, comprising delivering the therapeutic agent after balloon inflation. 4. The method of claim 1, comprising delivering the therapeutic agent during balloon inflation. 5. The method of claim 1, wherein the therapeutic agent is a pharmaceutical agent, a naturally occurring substance, a stem cell, an embryonic cell, a fetal cell, a transgenic cell, an adult human cell, a modified cell, a modified cellular agent, a sub-cellular structure, an agent capable of modifying cellular function or structure, or a combination thereof. 6. The method of claim 1, wherein the therapeutic port is used to aspirate the body fluids distal to the site of angioplasty. 7. The method of claim 1 where the therapeutic port is used to aspirate plaque debris suspended in a column of blood distal to the site of angioplasty. 8. The method of claim 1, further comprising inserting the tubular body into the vessel already protected by a previously placed emboli protection device. 9. The method of claim 8, wherein the emboli protection device is a distal filter. 10. The method of claim 8, wherein the emboli protection device is a distal occlusion device. 11. The method of claim 8, wherein the emboli protection device is a proximal occlusion device. 12. The method of claim 1, further comprising administering the therapeutic agent before balloon inflation. 13. The method of claim 1, further comprising administering the therapeutic agent during balloon inflation. 14. The method of claim 1, further comprising administering the therapeutic agent after balloon inflation. 15. The method of claim 1, further comprising aspirating body fluid before, during or after balloon inflation. 16. A method stent delivery with an angioplasty balloon catheter apparatus, the method comprising: providing an elongate flexible tubular body having a proximal end, a distal end, an outer wall, and an inner wall for insertion into a vessel;defining within the tubular body a first lumen defined by the inner wall, the first lumen having a port at the proximal end and a mouth at the distal end, the port being in fluid communication with the first lumen and the mouth;providing a guidewire lumen adjacent the first lumen and having a proximal end and a distal opening, the guidewire lumen being adapted to receive a standard-size coronary guidewire therethrough, and positioning the guidewire lumen adjacent to the first lumen such that the first lumen and the guidewire lumen near the distal end form essentially a figure eight configuration, wherein the guidewire lumen is provided on the interior of the tubular body, and positioning the guidewire lumen to extend distally from the mouth;providing an inflation channel extending through the tubular body and capable of delivering inflation pressure to an angioplasty balloon of the catheter, the inflation channel having a non-inflated state and an inflated state; andpositioning a stent on the angioplasty balloon, the stent being in a non-deployed position when the inflation channel is in a non-inflated state and the stent being in a deployed position when the inflation channel is in the inflated state;coupling a therapeutic source to the first port for delivering a therapeutic agent to the first lumen or coupling an aspiration source for aspirating body fluid through the first lumen; andinflating the inflation channel to place the stent in the deployed state. 17. The method of claim 16, wherein coupling the therapeutic source to the first port for delivering the therapeutic agent to the first lumen or coupling the aspiration source for aspirating the body fluid through the first lumen occurs before stent deployment. 18. The method of claim 16, wherein coupling the therapeutic source to the first port for delivering the therapeutic agent to the first lumen or coupling the aspiration source for aspirating the body fluid through the first lumen occurs after stent deployment. 19. The method of claim 16, wherein coupling the therapeutic source to the first port for delivering the therapeutic agent to the first lumen or coupling the aspiration source for aspirating the body fluid through the first lumen occurs during stent deployment.
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