[특허]Implantable materials having engineered surfaces and method of making same

[미국특허] Implantable materials having engineered surfaces and method of making same 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61F-002/02 A61F-002/06
출원번호	US-0428981 (2009-04-23)
등록번호	US-8268340 (2012-09-18)
발명자 / 주소	Choubey, Animesh Palmaz, Julio C.
출원인 / 주소	Advanced Bio Prosthetic Surfaces, Ltd.
대리인 / 주소	Paredes, J. Peter
인용정보	피인용 횟수 : 2 인용 특허 : 50

초록

Implantable materials having engineered surfaces and method of making same comprising geometric features on at least one surface of the material having at least one of chemical, physiochemical and electrochemical activity different than regions of the at least one surface without the features.

대표청구항 ▼

1. An implantable, biocompatible metal material, comprising at least one surface of the biocompatible metal material, wherein the at least one surface has an array of geometric features on the at least one surface thereof, wherein each of the geometric features has a chemically etched surface having a grain structure and a plurality of grain boundaries surrounding the grain structure, wherein the plurality of grain boundaries have a higher amount of positive charge as compared to the grain structure to promote the formation of an endothelial cell layer. 2. The implantable, biocompatible metal material according to claim 1, wherein the plurality of grain boundaries is the dividing structure between two adjacent grain structures that have different crystallographic orientations. 3. The implantable, biocompatible metal material according to claim 2, wherein the grain surface and the grain boundaries have an average roughness of about 10-160 μm. 4. The implantable, biocompatible metal material according to claim 2, wherein the grain structure has a positive charge concentration of about −0.2 to −0.3 nN and the grain boundaries have positive charge concentration between about −0.80 to −1.0 nN. 5. The implantable, biocompatible metal material according to claim 4, wherein the grain boundaries have a width and depth between about 1 μm to about 2 μm. 6. The implantable, biocompatible metal material according to claim 2, wherein each of the geometric features has a structural feature selected from at least one of: deep and narrow crevices, protrusions, and a smooth surface on the grains. 7. The implantable, biocompatible metal material according to claim 2, wherein the grain structure has a surface area of about 10-150 μm2. 8. The implantable, biocompatible metal material according to claim 5, wherein at least one of the geometric features further comprises a drug coating along the grain boundaries and within the grain structure. 9. The implantable, biocompatible metal material according to claim 8, wherein the drug coating comprises negatively charged molecules. 10. The implantable, biocompatible metal material according to claim 2, wherein the biocompatible metal material is stainless steel. 11. The implantable, biocompatible metal material according to claim 2, wherein the biocompatible metal is nitinol.

이 특허에 인용된 특허 (50) 인용/피인용 타임라인 분석

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이 특허를 인용한 특허 (2) 인용/피인용 타임라인 분석

Palmaz, Julio C.; Boyle, Christopher T., Compliant implantable medical devices and methods of making same.
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Palmaz, Julio C.; Boyle, Christopher T., Compliant implantable medical devices and methods of making same.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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[미국특허] Implantable materials having engineered surfaces and method of making same 원문보기