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| 국가/구분 | United States(US) Patent 등록 |
|---|---|
| 국제특허분류(IPC7판) |
|
| 출원번호 | US-0267518 (2008-11-07) |
| 등록번호 | US-8287453 (2012-10-16) |
| 발명자 / 주소 |
|
| 출원인 / 주소 |
|
| 대리인 / 주소 |
|
| 인용정보 | 피인용 횟수 : 22 인용 특허 : 743 |
Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a
Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
1. A method for determining a stability of an analyte sensor, the method comprising: exposing an analyte sensor to a biological sample, wherein the analyte sensor comprises a first working electrode that measures an analyte component and a baseline component and a second working electrode that measu
1. A method for determining a stability of an analyte sensor, the method comprising: exposing an analyte sensor to a biological sample, wherein the analyte sensor comprises a first working electrode that measures an analyte component and a baseline component and a second working electrode that measures a baseline component substantially without an analyte component;receiving sensor data from the analyte sensor, wherein the sensor data comprises first sensor data associated with the first working electrode and second sensor data associated with the second working electrode; anddetermining, using a processor module, a stability of the analyte sensor based at least in part on the second sensor data. 2. The method of claim 1, wherein the second sensor data comprises a plurality of time spaced data points, and wherein the step of determining a stability of the analyte sensor comprises evaluating a change in amplitude of two or more of the plurality of time spaced data points. 3. The method of claim 2, wherein the step of exposing the analyte sensor to a biological sample comprises intermittently exposing the analyte sensor to a biological sample and to an infusion solution. 4. The method of claim 3, wherein the step of evaluating comprises comparing a plurality of time spaced points measured when the analyte sensor is exposed to the biological sample. 5. The method of claim 3, wherein the step of evaluating comprises comparing a first point measured when the analyte sensor is exposed to the biological sample to a second point measured when the analyte sensor is exposed to the infusion solution. 6. The method of claim 3, wherein the step of evaluating comprises evaluating transient information of the second sensor data during a step change from exposure of the sensor to the infusion solution to exposure of the sensor to the biological sample. 7. The method of claim 2, further comprising determining a predetermined level of stability when a change in an amplitude of the second sensor data meets one or more criteria. 8. The method of claim 7, further comprising controlling a display associated with the analyte sensor system in response to the determination of the predetermined level of stability. 9. The method of claim 8, wherein the step of controlling a display comprises providing at least one of a numeric estimated analyte value, a directional trend of analyte concentration, and a graphical representation of a plurality of estimated analyte values. 10. The method of claim 8, wherein the step of controlling a display comprises requesting reference analyte data. 11. The method of claim 1, wherein the step of determining a stability of the analyte sensor is performed during a predetermined time period. 12. The method of claim 1, wherein the step of determining a stability of the analyte sensor is performed after a predetermined time period. 13. The method of claim 1, further comprising repeating the step of determining a stability, wherein the step is conducted after a system re-start. 14. The method of claim 1, wherein the analyte sensor is a glucose sensor. 15. A system for determining a stability of an analyte sensor, the system comprising: an analyte sensor; anda computer system, the computer system comprising: an input module operatively connected to the analyte sensor and configured to receive sensor data from an analyte sensor, wherein the analyte sensor comprises a first working electrode configured to provide first sensor data comprising an analyte component and a baseline component and a second working electrode configured to provide second sensor data comprising a baseline component substantially without an analyte component; anda processor module configured to determine a stability of the analyte sensor based at least in part on the second sensor data. 16. The system of claim 15, wherein the processor module is configured to determine a stability of the analyte sensor at least in part by evaluating a change in amplitude of a plurality of time spaced points from the second sensor data. 17. The system of claim 16, wherein the system further comprises a flow control device configured and arranged to intermittently expose the analyte sensor to a biological sample and to an infusion solution. 18. The system of claim 17, wherein the processor module is configured to evaluate the change in amplitude at least in part by comparing a plurality of time spaced points from the second sensor data measured when the analyte sensor is exposed to the biological sample. 19. The system of claim 17, wherein the processor module is configured to evaluate the change in amplitude at least in part by comparing a first point measured when the analyte sensor is exposed to the biological sample to a second point measured when the analyte sensor is exposed to the infusion solution. 20. The system of claim 17, wherein the processor module is configured to evaluate the change in amplitude at least in part by evaluating transient information of the second sensor data during a step change from exposure of the sensor to the infusion solution to exposure of the sensor to the biological sample. 21. The system of claim 16, wherein the processor module is configured to determine a level of stability when a change in amplitude of a plurality of time spaced points from the second sensor data meets one or more criteria. 22. The system of claim 21, wherein the processor module is configured to control a display of calibrated sensor based at least in part on the level of stability. 23. The system of claim 22, wherein the calibrated sensor data comprises at least one of a numeric estimated analyte value, a directional trend of analyte concentration, and a graphical representation of a plurality of estimated analyte values. 24. The system of claim 21, wherein the processor module is configured to request reference analyte data based at least in part on the level of stability. 25. The system of claim 15, wherein the processor module is further configured to determine a stability of the analyte sensor during a predetermined time period. 26. The system of claim 15, wherein processor module is further configured to determine a stability of the analyte sensor after a predetermined time period. 27. The system of claim 15, wherein the analyte sensor is a glucose sensor.
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