Method of producing high alcohol content foaming compositions with silicone-based surfactants
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A01N-025/00
A61K-031/74
A61K-051/00
A61M-036/14
출원번호
US-0806767
(2007-06-04)
등록번호
US-8313758
(2012-11-20)
발명자
/ 주소
Fernandez de Castro, Maria Teresa
Koivisto, Bruce Michael
Munoz, Francisco
출원인 / 주소
Deb Worldwide Healthcare Inc.
대리인 / 주소
Neal, Gerber & Eisenberg LLP
인용정보
피인용 횟수 :
0인용 특허 :
224
초록▼
This invention relates to a method of producing and dispensing a foam using a “high lower alcohol content”(40% v/v of a C1-4 alcohol) liquid composition. The liquid compositions comprise an alcohol, C1-4(40% v/v), a silicone-based surfactant of at least 0.001% by weight to prepare a foamable composi
This invention relates to a method of producing and dispensing a foam using a “high lower alcohol content”(40% v/v of a C1-4 alcohol) liquid composition. The liquid compositions comprise an alcohol, C1-4(40% v/v), a silicone-based surfactant of at least 0.001% by weight to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and mosturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.
대표청구항▼
1. A method of producing and dispensing a foam using a foamable alcohol composition, the method comprising: dispensing a foamable alcohol composition from a container having a dispenser pump configured to mix air with the foamable alcohol composition under low pressure during dispensing to form a fo
1. A method of producing and dispensing a foam using a foamable alcohol composition, the method comprising: dispensing a foamable alcohol composition from a container having a dispenser pump configured to mix air with the foamable alcohol composition under low pressure during dispensing to form a foam, the foamable alcohol composition comprising: i) a C1-4 alcohol, or mixtures thereof, present in an amount greater than 60% v/v of the total composition;ii) an effective physiologically acceptable silicone-based surfactant, comprising a lipophilic chain containing a silicone backbone for foaming present in an amount of at least 0.5% by weight of the total composition; andiii) water present in an amount to balance the total composition to 100% by weight. 2. The method according to claim 1 wherein the dispenser is an unpressurized dispenser and whereby when a user activates the dispenser pump air is mixed with the composition under low pressure. 3. The method according to claim 1 wherein the effective silicone-based surfactant for foaming is physiologically compatible, and wherein the silicone-based surfactant is selected from the group consisting of silicone ethoxylates, silicone glycerol esters, silicone amine oxides, silicone acetylenic alcohol, silicone carboxylates, silicone sulphates, silicone phosphates, silicone imidazole quats, silicone amino quats, silicone phosphate esters, silicone carbohydrate, silicone isethionates, silicone sulfonates, silicone betaines, silicone amino propionates, silicone esters, silicone polyamides, and silicone hydrocarbon surfactants. 4. The method according to claim 1, wherein the effective physiologically acceptable silicone-based surfactant is selected from the group consisting of polyether-modified polysiloxanes, polysiloxane betaines and mixtures thereof, present in an amount up to about 10.0% by weight of the total composition. 5. The method according to claim 1, wherein the alcohol is selected from the group consisting of ethanol, n-propanol, a mixture of ethanol and n-propanol and a mixture of ethanol and isopropanol, present in an amount of at least 60% v/v. 6. The method according to claim 1, wherein the alcohol is isopropanol present in an amount of at least 70% v/v. 7. The method according to claim 1, further comprising at least one additional surfactant present in an amount no more than 1% by weight for adjusting properties of the foam produced from the composition. 8. The method according to claim 7 wherein the additional surfactant is selected from the group consisting of alkylglucosides, a poly(ethoxylated and/or propoxylated) alcohol, a poly(ethoxylated and/or propoxylated) ester, an alkyl alcohol, an alkenyl alcohol, an ester of a polyhydric alcohol, an ether of a polyhydric alcohol, a sorbitan fatty acid ester, a betaine, a sulfobetaine, an imidazoline, an amino acid, a lecithin, a phosphatide, an amine oxide, a sulfoxide and mixtures thereof. 9. The method according to claim 8 wherein the betaine is cocamidopropyl betaine. 10. The method according to claim 8 wherein the alkylglucoside is cocoglucoside. 11. The method according to claim 1 further comprising a foam stabilizing agent present in an amount up to about 10% by weight of the total composition. 12. The method according to claim 11 wherein the foam stabilizing agent is selected from the group consisting of lactic acid esters of monoglycerides,cationic emulsifiers,quaternary ammonium compounds,triquaternized stearic phospholipid complex,hydroxystearamide propyltriamine salts,lactic acid monoglycerides,food emulsifiers selected from the group consisting of glyceryl monostearate, propylene glycol monostearate, and sodium stearoyl lactylate,cetyl betaine,glycolether,butyleneglycol,silicone wax,an encapsulated oil,microcapsule mineral oil,glycerine,2-butoxyethanol,behentrimonium chloride,cetrimonium chloride,and combinations thereof. 13. The method according to claim 1 further comprising one or more moisturizers, emollients, lipid layer enhancers or combinations thereof selected from the group consisting of lanolin,vinyl alcohol,polyvinyl pyrrolidone,polyols selected from the group consisting of glycerol, propylene glycol, butyleneglycol, glyceryl oleate and sorbitol,cocoglucoside,a fatty alcohol selected from the group consisting of cetyl alcohol, stearyl alcohol, lauryl alcohol, myristyl alcohol and palmityl alcohol,ceteareth 20,an alkylglucoside,mixtures of alkylglucoside and glyceryl oleate,PEG-200 hydrogenated glyceryl palmate, dihydroxypropyl PEG-5 linoleammonium chloride,PEG-7 glyceryl cocoate, and combinations thereof, present in an amount up to about 5% by weight of the total composition. 14. The method according to claim 1 further comprising an acid or a base to adjust a pH of the composition to a pre-selected pH present in an amount from about 0.05 to about 0.5 by weight of the total composition. 15. The method according to claim 1 further comprising a preservative in an amount from about 0.01 to about 5% by weight of the total composition. 16. The method according to claim 1 further comprising an antimicrobial agent selected from the group consisting of chlorhexidine salts, iodine, complexed forms of iodine, parachlorometaxylenol, triclosan, hexachlorophene, a phenol, hydrogen peroxide, silver, a silver salt, silver oxide, behenyl alcohol, and mixtures thereof. 17. The method according to claim 1 further comprising constituents selected from the group consisting of organic gums and colloids, lower alkanolamides of higher fatty acids, short chain diols and/or triols, fragrance, coloring matter, ultraviolet absorbers, solvents, buffers, conditioning agents, antioxidants, bactericides and medicinally active ingredients, and combinations thereof. 18. The method according to claim 1 wherein said alcohol C1-4, or mixtures thereof, is present in an amount between about 60% to about 80% v/v of the total composition and said effective physiologically acceptable silicone-based surfactant is present in an amount from 0.5% to about 10.0% by weight of the total composition, and wherein said composition further comprises a foam stabilizing agent present in an amount from about 0.01 to about 12.0% by weight of the total composition. 19. The method according to claim 18 in which said composition is formulated as a “leave-on” product not requiring washing after use of the foam. 20. The method according to claim 1 wherein the physiologically acceptable silicone-based surfactant is present in a range from 0.5% to about 10.0% by weight of the total composition. 21. The method according to claim 1 wherein the physiologically acceptable silicone-based surfactant consists essentially of a polyether-modified polysiloxane. 22. The method according to claim 1 wherein the silicone-based surfactant is a Bis-PEG-[10-20] dimethicone. 23. The method according to claim 22 wherein the foamable alcohol composition further comprises a foam stabilizing agent selected from the group consisting of cationic emulsifiers and quaternary ammonium compounds. 24. The method according to claim 22 wherein the foamable alcohol composition further comprises a foam stabilizing agent selected from the group consisting of 2-butoxyethanol, glycerine, butyleneglycol, cetrimonium chloride, and behentrimonium chloride. 25. The method according to claim 22 wherein the foamable alcohol composition further comprises behentrimonium chloride. 26. The method according to claim 1 wherein the silicone-based surfactant is a dimethicone copolyol. 27. The method according to claim 1 wherein the silicone-based surfactant is a linear-difunctional silicone surfactant. 28. The method according to claim 1 wherein the silicone-based surfactant is a PEG/PPG dimethicone surfactant. 29. The method according to claim 1 wherein the mixture comprises ethanol and isopropanol. 30. The method according to claim 1 wherein the mixture further comprises a fragrance. 31. The method according to claim 1, wherein the mixture further comprises glycerol and propylene glycol. 32. The method according to claim 1, wherein the foamable alcohol composition further comprises PEG-7 glyceryl cocoate.
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