최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0474680 (2009-05-29) |
등록번호 | US-8333197 (2012-12-18) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 12 인용 특허 : 453 |
Devices and methods of entraining a substance within an airflow are disclosed. Condensation aerosol delivery devices and methods of consistently producing multiple doses of a substance, such as a drug, having high purity, high yield, characterized by a particle size distribution appropriate for pulm
Devices and methods of entraining a substance within an airflow are disclosed. Condensation aerosol delivery devices and methods of consistently producing multiple doses of a substance, such as a drug, having high purity, high yield, characterized by a particle size distribution appropriate for pulmonary delivery, and which can be administered to a user in a single dose are also disclosed.
1. A device for delivering a condensation aerosol comprising a substance to a subject comprising: a dispensing unit comprising: a first housing comprising a receptacle for a separable cartridge;a controller for controlling vaporization of the substance; anda power source; anda separable cartridge co
1. A device for delivering a condensation aerosol comprising a substance to a subject comprising: a dispensing unit comprising: a first housing comprising a receptacle for a separable cartridge;a controller for controlling vaporization of the substance; anda power source; anda separable cartridge comprising: a second housing;an airway contained within the housing having an inlet, andan outlet;a mouthpiece coupled to the outlet;a plurality of electrically resistive heating elements disposed within the airway;the substance disposed on at least one electrically resistive heating element of the plurality of electrically resistive heating elements; andan actuation mechanism configured to transfer energy from the power source to each of the electrically resistive heating elements of the plurality of electrically resistive heating elements, which have a substance disposed thereon;wherein an airflow from the inlet to the outlet of the airway causes the substance to vaporize and condense in the airflow to form a condensation aerosol. 2. The device of claim 1, further comprising an air bypass hole coupled to the outlet of the second housing. 3. The device of claim 1, wherein the amount of substance disposed on the at least electrically resistive heating element comprises a therapeutically effective amount of at least one physiologically active compound. 4. The device of claim 1, wherein each electrically resistive heating element comprises a metal foil. 5. The device of claim 4, wherein the metal foil is arched. 6. The device of claim 1, wherein the substance is disposed on the electrically resistive heating element as a layer and the thickness of the layer ranges from 0.01 μm to 20 μm. 7. The device of claim 1, wherein the airflow passing through the outlet ranges from 10 liters/min to 100 liters/min. 8. The device of claim 1, wherein the airway has a cross-sectional area that ranges from 0.5 cm2 to 3 cm2. 9. The device of claim 1, wherein the controller records and stores in a memory information pertaining to a specific cartridge and the interaction between a subject and the dispensing unit. 10. A method of administering a substance to a subject comprising: providing a device according to claim 1;providing an airflow in the airway;vaporizing the substance to produce a condensation aerosol comprising the substance in the airflow; andcontacting the subject with the condensation aerosol. 11. The method of claim 10, wherein the subject is contacted by inhaling the condensation aerosol. 12. The method of claim 10, wherein at least 80% of the substance disposed on each electrically resistive heating element passes through the outlet of the device. 13. The method of claim 10, wherein the condensation aerosol has a purity of at least 95%.
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